LA JOLLA, CA - November 15, 2018 - Scientists at Scripps Research have discovered that a mysterious family of cellular proteins called OSCAs and TMEM63s are a novel class of mechanosensitive ion channels.
WEST LAFAYETTE, Ind. -- Diabetes can lead to ulcers that patients don't even feel or notice until the sight of blood. And because ulcers can't heal on their own, 14 to 24 percent of diabetics in the U.S. who experience them end up losing their toes, foot or leg.
Purdue University researchers have developed a shoe insole that could help make the healing process more portable for the 15 percent of Americans who develop ulcers as a result of diabetes.
Dublin, Ireland: Researchers investigating new treatments for neuroblastoma - one of the most common childhood cancers - have found that a combination of two drugs made tumours disappear in mice, making it more effective than any other drugs tested in these animals.
Dublin, Ireland: Early results from a phase I trial in a small group of patients with advanced cancer using two drugs (nivolumab and pixatimod) that stimulate the immune system report that patients with bowel cancer may benefit from the combination.
Dublin, Ireland: A combination of two drugs, which prompt the body's immune system to identify and kill cancer cells, is a safe treatment for patients with advanced non-small cell lung cancer and has shown some signs of efficacy.
Fuel cells that work with the enzyme hydrogenase are, in principle, just as efficient as those that contain the expensive precious metal platinum as a catalyst. However, the enzymes need an aqueous environment, which makes it difficult for the starting material for the reaction - hydrogen - to reach the enzyme-loaded electrode. Researchers solved this problem by combining previously developed concepts for packaging the enzymes with gas diffusion electrode technology.
The mesosphere, at heights between 85 and 100 kilometers above the Earth's surface, contains a layer of atomic sodium. Astronomers use laser beams to create artificial stars, or laser guide stars (LGS), in this layer for improving the quality of astronomical observations. In 2011, researchers proposed that artificial guide stars could also be used to measure the Earth's magnetic field in the mesosphere. An international group of scientists has recently managed to do this with a high degree of precision.
SARASOTA, Fla. (November 14, 2018)- The century-old train car known to be the site of business transactions for the Ringling Bros. and Barnum & Bailey Circus has long been too fragile for visitors to step inside. The Wisconsin has faced conservation issues due to the discontinuation of spare train parts. Through a project led by the University of South Florida, it will no longer be limited to glancing through a window.
Dublin, Ireland: An antibody that binds simultaneously to two distinct regions of the HER2 receptor to block the growth of cancer cells has shown promising signs of anti-tumour activity in a number of cancers including those of the gullet (oesophagus), stomach and bowel.
Dublin, Ireland: A new drug designed to make radiotherapy more effective in treating cancer has been given to patients while they are receiving radiation and shown to be safe, according to research presented today (Wednesday) at the 30th EORTC-NCI-AACR  Symposium on Molecular Targets and Cancer Therapeutics in Dublin, Ireland.