Scientists at St. Jude Children's Research Hospital are advancing understanding of a potential Alzheimer's disease treatment. The work focuses on LC3-associated endocytosis (LANDO) and its role in neuroinflammation. The results appeared as an advance online publication today in Science Advances.
Women are having a difficult time getting into treatment for opioid addictions, according to a Vanderbilt University Medical Center study published today in JAMA Network Open.
The "secret shopper" study used trained actors attempting to get into treatment with an addiction provider in 10 U.S. states. The results, with more than 10,000 unique patients, revealed numerous challenges in scheduling a first-time appointment to receive medications for opioid use disorder, including finding a provider who takes insurance rather than cash.
A new design for light-emitting diodes (LEDs) developed by a team including scientists at the National Institute of Standards and Technology (NIST) may hold the key to overcoming a long-standing limitation in the light sources' efficiency. The concept, demonstrated with microscopic LEDs in the lab, achieves a dramatic increase in brightness as well as the ability to create laser light -- all characteristics that could make it valuable in a range of large-scale and miniaturized applications.
Doctors can predict patients' risk for ischemic stroke based on the severity of their metabolic syndrome, a conglomeration of conditions that includes high blood pressure, abnormal cholesterol levels and excess body fat around the abdomen and waist, a new study finds.
Molecular and computational biologists from Peter the Great St. Petersburg Polytechnic University (SPbPU), St. Petersburg State University and Federal Centre for Bast Fiber Crops teamed up to sequence and assemble genome of Fusarium oxysporum f.sp. lini, a highly destructive fungal parasite infecting flax. The results of the study were published in the Molecular Plant-Microbe Interactions.
When Anthropologist Caroline Arcini and her colleagues at the Swedish Natural Historical Museum discovered small calcifications in the extremely well preserved lungs of Bishop Peder Winstrup, they knew more investigation was needed. "We suspected these were remnants of a past lung infection," says Arcini, "and tuberculosis was at the top of our list of candidates. DNA analysis was the best way to prove it."
The co-authors, Associate Professor Dinar Fazullin and Associate Professor Gennady Mavrin, have been engaged in the topic of membrane elements for water purification for ten years. This research area is very pertinent because of the large volumes of liquid waste and a lack of specialized types of membranes.
Two common variants in the KIF3A gene increase the risk of young children having a dysfunctional skin barrier and developing the skin condition atopic dermatitis. This, in turn, can allow environmental exposures to more easily cross the skin barrier and contribute to the development of food allergies and asthma as they grow up.
UNIVERSITY PARK, Pa. -- While many programs and initiatives have been implemented to address the prevalence of substance abuse among homeless youth in the United States, they don't always include data-driven insights about environmental and psychological factors that could contribute to an individual's likelihood of developing a substance use disorder.
HERSHEY, Pa. -- Pregnant women from sub-Saharan Africa with malaria and human immunodeficiency virus (HIV) have a higher prevalence of anemia than pregnant women without infections, according to Penn State College of Medicine researchers. The findings may have implications for reducing the risk of death in pregnant women and preventing low birth weights and neurocognitive impairment in their children as a result of anemia.
Swansea University researchers from the College of Engineering have captured the moments a fluid reacts like a solid through a new method of fluid observation under pressurised conditions.
The research comes from the Complex Flow Lab, based within the Institute for Innovative Materials, Processing and Numerical Technologies (IMPACT). The lab studies the intricate flow patterns that often develop in granular materials, porous media, and complex fluids such as foams, gels and pastes.
UNIVERSITY PARK, Pa. -- Fungal spores responsible for bitter rot disease, a common and devastating infection in fruit, do not encounter their host plants by chance. Turns out, they have a symbiotic association with the plant, often living inside its leaves.
The new way of looking at the fungal pathogen, Colletotrichum fioriniae, as a leaf endophyte -- bacterial or fungal microorganisms that colonize healthy plant tissue -- was the outcome of a two-year study conducted by researchers in Penn State's College of Agricultural Sciences.
PHOENIX, Ariz. -- Aug. 14, 2020 -- A review article authored by a researcher at the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggests that following menopause, women are at higher risk for developing nonalcoholic fatty liver disease (NAFLD), a chronic condition caused by the build-up of excess fat in the liver not caused by alcohol.
First appearing in late 2019 in Wuhan City, China, the SARS-CoV-2 virus continues to cause sickness and death across the globe. Researchers and scientists have been looking at multiple solutions to treat COVID-19, including repurposing approved pharmaceutical drugs. This research points to very promising treatment options.
A team of researchers at the Pritzker School of Molecular Engineering (PME) at the University of Chicago used state-of-the-art computer simulations to identify a preexisting drug that could fast-track a solution to this worldwide pandemic.
If you want to enhance a locust to be used as a bomb-sniffing bug, there are a few technical challenges that need solving before sending it into the field.
Is there some way to direct the locust -- to tell it where to go to do its sniffing? And because the locusts can't speak (yet), is there a way to read the brain of these cyborg bugs to know what they're smelling?
For that matter, can locusts even smell explosives?