Toronto - (January 17, 2020) In an unprecedented pan-cancer analysis of whole genomes, researchers at the Ontario Institute for Cancer Research (OICR) have discovered new regions of non-coding DNA that, when altered, may lead to cancer growth and progression.

The study, published today in Molecular Cell, reveals novel mechanisms of disease progression that could lead to new avenues of research and ultimately to better diagnostic tests and precision therapies.

Ever since it was proposed that atoms are building blocks of the world, scientists have been trying to understand how and why they bond to each other. Be it a molecule (which is a group of atoms joined together in a particular fashion), or a block of material or a whole living organism, ultimately, everything is controlled by the way atoms bond, and the way bonds break.

HANOVER, N.H. - January 17, 2020 - Researchers from Dartmouth and the Massachusetts Institute of Technology (MIT) have developed an original approach to flight scheduling that, if implemented, could result in a significant increase in profits for airlines and more flights that align with passengers' preferences.

WASHINGTON, January 17, 2020 -- Specially designed vacuum suction units allow humans to climb walls. Scientists have developed a suction unit that can be used on rough surfaces, no matter how textured, and that has applications in the development of climbing robots and robotic arms with grasping capabilities.

Traditional methods of vacuum suction and previous vacuum suction devices cannot maintain suction on rough surfaces due to vacuum leakage, which leads to suction failure.

CHARLOTTESVILLE, Va. - The Association for Computing Machinery has named Matthew B. Dwyer, a University of Virginia professor of computer science, a fellow. Fellowships are conferred to association members for technological accomplishments that help define the digital age and improve professional and personal lives. Association for Computing Machinery Fellows comprise an elite group that represents less than 1% of the association's global membership.

CHARLOTTESVILLE, Va. - UVA Engineering computer science professor Jack W. Davidson has been named an Institute of Electrical and Electronics Engineers Fellow in recognition of his contributions to compilers, computer security and computer science education.

BIRMINGHAM, Ala. - The lungs and placentas of fetuses in the womb -- as young as 11 weeks after conception -- already show a bacterial microbiome signature, which suggests that bacteria may colonize the lungs well before birth. This first-time finding deepens the mystery of how the microbes or microbial products reach those organs before birth and what role they play in normal lung and immune system development.

WEST LAFAYETTE, Ind. -- Manufacturing prescription drugs with distinct markings, colors, shapes or packaging isn't enough to protect them from counterfeiting, U.S. Drug Enforcement Administration reports have shown.

Purdue University researchers are aiming to stump counterfeiters with an edible "security tag" embedded into medicine. To imitate the drug, a counterfeiter would have to uncrack a complicated puzzle of patterns not fully visible to the naked eye.

Skokie, IL - The ISSCR is updating its Guidelines for Stem Cell Research and Clinical Translation to respond to recent scientific advances that include the use of pluripotent stem cell (PSC) to create models of early human embryo development (see Stem Cell Reports 14:1-6). As the science continues to advance, it raises important scientific, clinical, ethical, and societal issues for researchers, regulators, and funding agencies. The ISSCR believes the scientific community must address these challenges to establish parameters for research in this area.

A research team at Kobe University has developed a method of artificially controlling the anchorage position of target proteins in engineered baker's yeast (Saccharomyces cerevisiae).

What The Study Did: Researchers report on a randomized clinical trial that compared two strategies (proton pump inhibitors vs. histamine-2 receptor blockers) to prevent stress ulcers among adult patients in intensive care units who needed mechanical ventilation. The trial was conducted at 50 ICUs in five countries to compare in-hospital death rates using the two strategies. The study is being released to coincide with presentation at the Critical Care Reviews Meeting 2020 in Belfast, Northern Ireland.

Globally, arenas and stadiums that seat tens of thousands of people are filling up for whole weekends with crowds excited to their favourite sports stars sit on chairs and stare at screens. These fans are here to watch men and women play computer games, and researchers from Aalto and Tampere University are studying why.

Roughness, the presence of irregularities on a surface, is commonly associated to slower motion and stickiness. This is true at different length scales: at human size (1 meter), it takes longer to walk along a path that goes up and down, rather than walking on a flat road. At the size of smaller objects (1/100 - 1/1000 meter), Italians use pasta shapes with a rough surface, e.g. rigatoni, to make better adhesive surfaces for the tomato sauce and cheese. Till now, however, no experiment was able to test if the behavior of molecules really follows the same trend observed at human scale.

University of Seville researchers, in collaboration with the University of Nottingham, have managed to create the first image of nanoparticles of stabilised gold with biodegradable and biocompatible systems that have been obtained with 3D-printng techniques. The image chosen for this test was the logo of the University of Seville.

PROVIDENCE, R.I. [Brown University] -- Nacre -- the iridescent part of mollusk shells -- is a poster child for biologically inspired design. Despite being made of brittle chalk, the intricately layered microstructure of nacre gives it a remarkable ability to resist the spread of cracks, a material property known as toughness.