All modern life is composed of cells, from single-celled bacteria to more complex organisms such as humans, which may contain billions or even trillions of cells, but how life came to be cellular remains uncertain. New research led by specially appointed assistant professor Tony Z.

Scientists are exploring a number of ways for people with disabilities to communicate with their thoughts. The newest and fastest turns back to a vintage means for expressing oneself: handwriting.

For the first time, researchers have deciphered the brain activity associated with trying to write letters by hand. Working with a participant with paralysis who has sensors implanted in his brain, the team used an algorithm to identify letters as he attempted to write them. Then, the system displayed the text on a screen - in real time.

Scientists have for the first time revealed the structure surrounding important receptors in the brain's hippocampus, the seat of memory and learning.

The study, carried out at Oregon Health & Science University, published today in the journal Nature.

The new study focuses on the organization and function of glutamate receptors, a type of neurotransmitter receptor involved in sensing signals between nerve cells in the hippocampus region of the brain. The study reveals the molecular structure of three major complexes of glutamate receptors in the hippocampus.

What The Study Did: Researchers describe overdose deaths in San Francisco before and after the initial COVID-19 shelter-in-place order to try to make clear whether characteristics of fatal overdoses changed during this time in an effort to guide future prevention efforts.

Authors: Luke N. Rodda, Ph.D., of the Office of the Chief Medical Examiner for the city and county of San Francisco, is the corresponding author.

What The Study Did: Rates of preterm birth and stillbirth in Ontario, Canada, during the first six months of the COVID-19 pandemic are evaluated in this study.

Authors: Andrea N. Simpson, M.D., M.Sc., of St Michael's Hospital, Unity Health Toronto, in Toronto, is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link


What The Study Did: Researchers used registry data to examine the number, characteristics and outcomes of patients with sunburns severe enough to warrant admission to specialist burn services in Australia and New Zealand.

Authors: Lincoln M. Tracy, Ph.D., of Monash University in Melbourne, Australia, is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link


What The Study Did: Delayed localized injection-site reactions to the Moderna COVID-19 vaccine for 16 patients are described in this report.

Authors: Alicia J. Little, M.D., Ph.D., of the Yale University School of Medicine in New Haven, Connecticut, is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link


HOUSTON - The mitochondrial enzyme dihydroorotate dehydrogenase (DHODH) plays an important and previously unknown role in blocking a form of cell death called ferroptosis, according to a new study published today in Nature by researchers at The University of Texas MD Anderson Cancer Center. Preclinical findings suggest that targeting DHODH can restore ferroptosis-driven cell death, pointing to new therapeutic strategies that may be used to induce ferroptosis and inhibit tumor growth.

A Johns Hopkins University-led team has created an inexpensive portable device and cellphone app to diagnose gonorrhea in less than 15 minutes and determine if a particular strain will respond to frontline antibiotics.

The invention improves on traditional testing in hospital laboratories and clinics, which typically takes up to a week to deliver results--time during which patients can unknowingly spread their infections. The team's results appear today in Science Translational Medicine.

Long-lasting, quick-charging batteries are essential to the expansion of the electric vehicle market, but today's lithium-ion batteries fall short of what's needed -- they're too heavy, too expensive and take too long to charge.

For decades, researchers have tried to harness the potential of solid-state, lithium-metal batteries, which hold substantially more energy in the same volume and charge in a fraction of the time compared to traditional lithium-ion batteries.

Scientists have developed a brain-computer interface (BCI) designed to restore the ability to communicate in people with spinal cord injuries and neurological disorders such as amyotrophic lateral sclerosis (ALS). This system has the potential to work more quickly than previous BCIs, and it does so by tapping into one of the oldest means of communications we have--handwriting.

Since the discovery of Alzheimer's disease over a century ago, two hallmarks of the devastating illness have taken center stage.

The first, known as amyloid plaques, are dense accumulations of misfolded amyloid protein, occurring in the spaces between nerve cells. Most efforts to halt the advance of Alzheimer's disease have targeted amyloid protein plaques. To date, all have met dispiriting failure.

Acetone, a volatile solvent used for everything from removing nail polish and cleaning textiles to manufacturing plastics, could get a sustainability boost from a new strain of bacteria engineered by a research team based in Japan.

They published the details of the heat-loving, acetone-producing bacteria called Moorella thermoacetica on April 23 in AMB Express.

The field of magnonics offers a new type of low-power information processing, in which magnons, the quanta of spin waves, carry and process data instead of electrons. The end goal of this field is to create magnonic circuits, which would be smaller and more energy-efficient than current electronic ones.

Mycobacterium tuberculosis is incredible in that it can survive for decades within its human host. It does this by varying its diet to successfully steal nutrients from the human host including immune cells; it is known to acquire and absorb multiple carbon sources from the body during infection.