Peer review/Experimental study/Cells

Researchers at Uppsala University have created the first 3D map of the hearing nerve showing where the various sound frequencies are captured. Using what is known as synchrotron X-ray imaging, they were able to trace the fine nerve threads and the vibrating auditory organ, the cochlea, and find out exactly how the frequencies of incoming sound are distributed. The study is published in Scientific Reports.

Genome variation data on more than 7,000 malaria parasites from 28 endemic countries is released today (24 February) in Wellcome Open Research. It has been produced by MalariaGEN, a data-sharing network of groups around the world who are working together to build high-quality data resources for malaria research and disease control.

BINGHAMTON, NY -- Ancestry estimation -- a method used by forensic anthropologists to determine ancestral origin by analyzing bone structures -- is rooted in "race science" and perpetuates white supremacy, according to a new paper by a forensic anthropologist at Binghamton University, State University of New York.

By themselves, bones seem somewhat uniform to the untrained eye. They lack the traits we so often use to categorize fellow humans: hair texture, the shape of nose and eye, skin pigmentation.

Before the corona pandemic, tens of millions international travellers annually headed to the tropics, getting exposed to local intestinal bacteria. A total of 20-70% of those returning from the tropics carry - for the most unknowingly - ESBL-producing bacteria resistant to multiple antibiotics. The likelihood of acquiring such superbacteria depends on destination and health behaviour abroad. The risk is greatest in South and Southeast Asia, and a substantial increase is associated with contracting travellers' diarrhoea and taking antibiotics while abroad.

Today's quantum computers contain up to several dozen memory and processing units, the so-called qubits. Severin Daiss, Stefan Langenfeld, and colleagues from the Max Planck Institute of Quantum Optics in Garching have successfully interconnected two such qubits located in different labs to a distributed quantum computer by linking the qubits with a 60-meter-long optical fiber. Over such a distance they realized a quantum-logic gate - the basic building block of a quantum computer. It makes the system the worldwide first prototype of a distributed quantum computer.

A new study, published today in Nature Digital Medicine, found that 'natural language processing' (NLP) of information routinely recorded by doctors - as part of patients' electronic health records - reveal vital trends that could help clinical teams forecast and plan for surges in patients.

Knowing the environmental and human-related variables that characterize the favorable areas for the incidence of the West Nile virus, a flavivirus that is transmitted from birds to humans by mosquitoes, is essential to identify those places in Europe at high risk of experiencing outbreaks, even before these are registered, thus enabling preventive measures to be taken.

With the voice commands "Alexa Skills," users can load numerous extra functions onto their Amazon voice assistant. However, these Skills can often have security gaps and data protection problems, as a team of researchers from the Horst Görtz Institute for IT Security at Ruhr-Universität Bochum (RUB) and North Carolina State University discovered, together with a former PhD student who started to work for Google during the project. They will present their work at the "Network and Distributed System Security Symposium (NDSS)" conference on 24 February 2021.

Torino, February 24, 2021 - The eukaryotic cell is the basic unit of animals and plants. At the microscope, it looks highly structured and subdivided in many membrane-bound compartments. Each compartment has a specific function, and its membrane is populated by specific molecules. How does the cell preserve this amazing internal order, and (in the absence of pathologies) does not degrade into a shapeless bunch of molecules?

Philadelphia, February 22, 2021--In April 2020, pediatricians began recognizing a puzzling syndrome in children involving hyperinflammation that results in an array of symptoms, including fever, gastrointestinal distress and rash. The syndrome, thought to be a post-infectious complication of SARS-CoV-2 infection, was given the name Multisystem Inflammatory Syndrome Children, or MIS-C. However, diagnosing the condition has posed challenges, as many of its symptoms, including rash, are common in many other pediatric infections.

Polished glass has been at the center of imaging systems for centuries. Their precise curvature enables lenses to focus light and produce sharp images, whether the object in view is a single cell, the page of a book, or a far-off galaxy.

Changing focus to see clearly at all these scales typically requires physically moving a lens, by tilting, sliding, or otherwise shifting the lens, usually with the help of mechanical parts that add to the bulk of microscopes and telescopes.

Abu Dhabi, UAE, February 22: By engineering common filter papers, similar to coffee filters, a team of NYU Abu Dhabi researchers have created high throughput arrays of miniaturized 3D tumor models to replicate key aspects of tumor physiology, which are absent in traditional drug testing platforms. With the new paper-based technology, the formed tumor models can be safely cryopreserved and stored for prolonged periods for on-demand drug testing use.

The team of Professor Dongling Ma of the Institut national de la recherche scientifique (INRS) developed a new approach for foldable and solid devices.

COLUMBUS, Ohio - Fool the novel coronavirus once and it can't cause infection of cells, new research suggests.

Scientists have developed protein fragments - called peptides - that fit snugly into a groove on the SARS-CoV-2 Spike protein that it would normally use to access a host cell. These peptides effectively trick the virus into "shaking hands" with a replica rather than with the actual protein on a cell's surface that lets the virus in.

Graphs -- data structures that show the relationship among objects -- are highly versatile. It's easy to imagine a graph depicting a social media network's web of connections. But graphs are also used in programs as diverse as content recommendation (what to watch next on Netflix?) and navigation (what's the quickest route to the beach?). As Ajay Brahmakshatriya summarizes: "graphs are basically everywhere."