Body

Alexandria, Va., USA -- As the global battle to understand and eliminate the coronavirus continues, a new study published in the Journal of Dental Research demonstrates that testing of oropharyngeal secretions (OS) may reduce the number of false negative results from nasal swab testing of patients who have seemingly recovered from the disease.

The vitality of preterm infants should be assessed with an Apgar score, a tool used to measure the health of newborns immediately after birth. That is the conclusion by researchers at Karolinska Institutet in Sweden who in a large observational study examined the value of Apgar scores for preterm infants. The findings are published in the New England Journal of Medicine.

An analysis of patient records in Canada provides important new insights into changing patterns of inpatient healthcare utilization. Between 2007 and 2016, standardized hospitalization rates declined for coronary artery and vascular disease, heart rhythm disorders, stroke, and heart failure but increased for some important conditions: acquired valvular heart disease; vascular cognitive impairment; and congenital heart disease.

New technique in which drugs make bacteria glow could help fight antibiotic resistance

A new technique could help reduce antibiotic prescribing by predicting which drugs could be effective in fighting bacteria within minutes.

Researchers have shown that a variation in the viral genome of Covid-19 improved its ability to infect human cells and helped it become the dominant strain circulating around the world today.

The study, published today in the journal Cell, shows the variation is more infectious in cell cultures under laboratory conditions. The variant, named 'D614G', makes a small but effective change in the 'spike' glycoprotein that protrudes from the surface of the virus, which it uses to enter and infect human cells.

MADISON, Wis. -- University of Wisconsin-Madison researchers have developed a safer and more efficient way to deliver a promising new method for treating cancer and liver disorders and for vaccination -- including a COVID-19 vaccine from Moderna Therapeutics that has advanced to clinical trials with humans.

New Rochelle, NY, July 2, 2020--The Editor-in-Chief of Human Gene Therapy, the first journal devoted to the field of gene therapy, and one of the world's leading experts on gene therapy have co-authored a new editorial, Moving Forward After Two Deaths in a Gene Therapy Trial of Myotubular Myopathy, in response to the news of two deaths in a now-halted gene therapy clinical trial.

Infecting some volunteers with COVID-19 may provide valuable insights for future rounds of vaccine testing, but would require very strict controls, argues a group of infectious disease experts in the New England Journal of Medicine.

DALLAS - July 2, 2020 - Two new studies led by UT Southwestern scientists outline how individual cells maintain their internal clocks, driven both through heritable and random means. These findings, published online May 1 in PNAS and May 27 in eLife, help explain how organisms' circadian clocks maintain flexibility and could offer insights into aging and cancer.

WASHINGTON--Health care providers may unintentionally expose patients to endocrine- disrupting chemicals (EDCs) by prescribing certain medications and using medical supplies, according to a perspective published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

WASHINGTON--People with endocrine disorders may see their condition worsen as a result of COVID-19, according to a new review published in the Journal of the Endocrine Society.

If there's one myth that has persisted through the years without much evidence, it's this: multiply your dog's age by seven to calculate how old they are in "human years." In other words, the old adage says, a four-year-old dog is similar in physiological age to a 28-year-old person.

The combination of ceftolozane with tazobactam broadens the range of antibiotic therapy in adults with severe infections of the lungs, the urinary tract, the renal pelvis and the abdominal cavity. In view of the increasing resistance development in bacteria, this drug combination is therefore an important additional treatment option.

Currently we are facing a dementia epidemic, estimations showing that by 2050 approximately 131 million people will be affected. Every 7 seconds a patient is diagnosed worldwide. Because the common forms of dementia occur in the elderly, delaying the onset or worsening of the cognitive impairment could translate into a significant reduction of the incidence of the disease. Estimations have shown that of the huge number of cases expected by 2050, roughly 23 million could be avoided if the onset of the disease could be delayed by 2 years.