Body

A new study suggests that a hormone known to prevent weight gain and normalize metabolism can also help maintain healthy muscles in mice. The findings present new possibilities for treating muscle-wasting conditions associated with age, obesity or cancer, according to scientists from the University of Southern California Leonard Davis School of Gerontology.

Peer review/Experimental study/Animals

Propranolol, a drug that is efficacious against infantile haemangiomas ("strawberry naevi", resembling birthmarks), can also be used to treat cerebral cavernous malformations, a condition characterised by misshapen blood vessels in the brain and elsewhere. This has been shown by researchers at Uppsala University in a new study published in the scientific journal Stroke.

DALLAS, Feb. 23, 2021 — Women face many female-specific risks for heart disease and stroke, including pregnancy, physical and emotional stress, sleep patterns and many physiological factors, according to multiple studies highlighted in this year’s Go Red for Women® special issue of the Journal of the American Heart Association, published online today.

Using an innovative computational approach to analyze vast brain cell gene expression datasets, researchers at MIT and Sorbonne Université have found that Huntington's disease may progress to advanced stages more because of a degradation of the cells' health maintenance systems than because of increased damage from the disease pathology itself.

Luxembourg, 23 February 2021 - At an online European Parliament workshop hosted by Deirdre Clune MEP (Ireland), Alzheimer Europe launched a new report "Data Sharing in Dementia Research", which reviews recent changes in EU research policy and sets out recommendations to improve data sharing in dementia research.

Huntington's disease is caused by a mutation in the Huntingtin gene (HTT), which appears in adults and features motor, cognitive and psychiatric alterations. The origin of this disease has been associated with the anomalous functioning of the mutated protein: mHTT, but recent data showed the involvement of other molecular mechanisms.

Eating a low quality diet, high in foods and food components associated with chronic inflammation, during pregnancy may be associated with an increased risk of obesity and excess body fat in children, especially during late-childhood. The findings are published the open access journal BMC Medicine.

DALLAS, Feb. 22, 2021 -- Exposure to what is considered low levels of air pollution over a long period of time can increase the risk of heart attack, stroke, atrial fibrillation and pneumonia among people ages 65 and older, according to new research published today in the American Heart Association's flagship journal Circulation.

DALLAS, Feb. 22, 2021 -- Twelve weeks of exercise training improved artery health and function in middle-aged and older men (ages 50-70 years) with low-to-normal testosterone levels, while testosterone therapy provided no benefits to the arteries, according to new research published today in Hypertension, an American Heart Association journal.

Unravelling the unique characteristics of cancer cells and finding less-harmful ways to stop their growth have long been a focus for cancer researchers worldwide. New findings, reported in Nature Communications, describe the discovery of a unique dependence of cancer cells on a particular protein, which could lead to desperately needed treatment for hard-to-treat cancers.

The publication caps off a series of groundbreaking studies appearing in Nature journals over the last month by members of a powerful international research collaboration.

Young pregnant women, who appear to have fully recovered from an acute injury that reduced their kidney function, have higher rates of significant problems like preeclampsia and low birthweight babies, problems which indicate their kidneys have not actually fully recovered.

Now scientists have developed a rodent model that is enabling studies to better understand, identify and ideally avoid this recently identified association, they report in the Journal of the American Society of Nephrology.

In a world as diverse as our own, the journey towards a sustainable future will look different depending on where in the world we live, according to a recent paper published in One Earth and led by McGill University, with researchers from the Stockholm Resilience Centre.

The first global-scale assessment of the role ecosystems play in providing sanitation finds that nature provides at least 18% of sanitation services in 48 cities worldwide, according to researchers in the United Kingdom and India. The study, published February 19 in the journal One Earth, estimates that more than 2 million cubic meters of the cities' human waste is processed each year without engineered infrastructure. This includes pit latrine waste that gradually filters through the soil--a natural process that cleans it before it reaches groundwater.

Women of minority races and ethnicities and with less education and income have had relatively lower access to 3D mammography, a technology that can improve breast cancer detection and decrease false alarms, according to research published today.

Nanoparticles used in drug delivery systems, bioimaging, and regenerative medicine migrate from tissues to lymphatic vessels after entering the body, so it is necessary to clarify the interaction between nanoparticles and lymphatic vessels. Although technology to observe the flow of nanoparticles through lymphatic vessels in vivo has been developed, there has been no method to evaluate the flow of nanoparticles in a more detailed and quantitative manner ex vivo.