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New research will be live in npj Digital Medicine on December 12, 2019, that will feature a machine learning app aimed at preventing patients from severe fall-related injuries and death.

This AI technology was developed by Houston Methodist and tested over an eight-month period to help address the growing concern of severe patient falls with seniors and the worry it causes their care-providers and care-givers.

HOW IT WORKS

(Boston)--Cigarette smoking changes the types of cells that are present in the respiratory track and some biological processes necessary for detoxification of cigarette smoke are restricted to specific types of cells.

Scientists from Australia and the US have discovered and identified the genetic cause of a previously unknown human autoinflammatory disease.

The researchers determined that the autoinflammatory disease, which they termed CRIA (cleavage-resistant RIPK1-induced autoinflammatory) syndrome, is caused by a mutation in a critical cell death component called RIPK1.

A research team has identified a new species of virus specific to insects that can be engineered to house genes from related viruses that cause diseases such as Zika and yellow fever. By serving as a platform for recombinant approaches, the new virus represents a flexible and non-infectious research tool for testing diagnostics and vaccines for various infectious diseases. Flaviviruses are a family of insect-transmitted viruses that can cause dangerous infections such as yellow fever, dengue and West Nile encephalitis.

Stanford University School of Medicine investigators have succeeded in distinguishing the molecular pathway responsible for an illicit drug's abuse potential from the one behind its propensity to make people feel sociable.

The discovery, described in a study to be published Dec. 11 in Science Translational Medicine, could lead to novel treatments for psychiatric disorders marked by social awkwardness and withdrawal.

The findings were made in mouse experiments.

A new technology to produce safer 'hybrid' viruses at high volumes for use in vaccines and diagnostics for mosquito-borne diseases has been developed at The University of Queensland.

Researchers from UQ and QIMR Berghofer Medical Research Institute have exploited the benign characteristics of the Binjari virus - inert to humans - to produce 'dangerous looking' mosquito-borne viruses such as Zika and dengue, but which cannot grow in humans or animals.

Patients with chronic pain caught between cardiovascular concerns about non-opioid analgesics and addiction risks of opioids, likely causing significant unmet need for pain relief.

A new study reveals the mechanism that helps pancreatic cancer cells avoid starvation within dense tumors by hijacking a process that pulls nutrients in from their surroundings.

Led by researchers at NYU Grossman School of Medicine, the study explains how changes in the gene RAS -- known to encourage the abnormal growth seen in 90 percent of pancreatic cancer patients - also accelerate a process that supplies the building blocks required for that growth.

"Proteins are the workers in the cell, and it's important to know their shape," says Chris Sander, PhD, director of Dana-Farber's cBio Center in the Department of Data Sciences. Sander and his colleagues have now demonstrated a powerful "experimental evolution" method to discover details of protein shape and function, and the method may find uses across a very broad spectrum of biomedical research.

OAK BROOK, Ill. - Deep learning, a type of artificial intelligence, can boost the power of MRI in predicting attention deficit hyperactivity disorder (ADHD), according to a study published in Radiology: Artificial Intelligence. Researchers said the approach could also have applications for other neurological conditions.

NEW YORK (December 11, 2019) -- Nearly 1-in-10 patients admitted to a New York hospital with no symptoms of diarrhea were found to be carriers of Clostridioides difficile (C. diff), suggesting infections originate outside the hospital setting more often than thought, according to a study published today in Infection Control & Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America.

What The Study Did: Researchers compared opioid prescribing at discharge from the Mayo Clinic in Jacksonville, Florida, across 25 procedures before and after a Florida law that mandated changes to opioid prescribing went into effect in 2018.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

Authors: Steven B. Porter, M.D., of the Mayo Clinic in Jacksonville, Florida, is the corresponding author.

(doi:10.1001/jamasurg.2019.4913)

Scientists evaluated mouse models used for developing new treatments for mood disorders associated with Huntington's disease and recommend which are most relevant and have greater potential for success. They report their results in the Journal of Huntington's Disease.

BUFFALO, N.Y. -- Participants who ate a diet high in red and processed meat, fried food, refined grains and high-fat dairy were three times more likely to develop an eye condition that damages the retina and affects a person's central vision, according to the results of a study from the University at Buffalo.

The condition is called late-stage age-related macular degeneration (AMD). AMD is an irreversible condition that affects a person's central vision, taking away their ability to drive, among other common daily activities.

Chronic inflammatory bowel diseases, such as Crohn's Disease and ulcerative colitis, are linked to abnormalities of the gut microbiota in humans and in animals. Patients generally present reduced bacterial diversity in their intestinal flora along with excessive levels of bacteria that express a protein called flagellin, which favors their mobility. This enables them to penetrate the layer of mucous that covers the intestinal wall and is usually sterile.