Body

DALLAS (SMU) - Think spending time with your kids and spouse is the key to your happiness? You may actually be happier getting together with your friends, said SMU psychology professor Nathan Hudson. 

Hudson's research finds that people report higher levels of well-being while hanging with their friends than they do with their romantic partner or children. In fact, being around romantic partners predicted the least amount of happiness among these three groups, reveals a study published in the Journal of Personality and Social Psychology.   

Researchers have gained a better understanding of the complexity of the environment in which T cells thrive and, by extension, the tolerance mechanisms of these cells which are an obstacle to cellular immunity.

Published in Nature Communications, the new study was directed by Dr. Marie-Ève Lebel, a post-doctoral intern at the Maisonneuve-Rosemont Hospital Research Centre, which is part of the Centre intégré universitaire de santé et de services sociaux de l'Est-de-l'Île-de-Montréal (CIUSSS-EMTL).

What The Study Did: Researchers in this observational study examined the association between wearing eyeglasses daily and susceptibility to COVID-19.

Authors: Yiping Wei, M.D., Ph.D., and Jianjun Xu, M.D., Ph.D., of the Second Affiliated Hospital of Nanchang University in Nanchang, China, are the corresponding authors.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamaophthalmol.2020.3906)

DALLAS - Sept. 15, 2020 - Conditions related to obesity, including inflammation and leaky gut, leave the lungs of obese patients more susceptible to COVID-19 and may explain why they are more likely to die from the disease, UTSW scientists say in a new article published online in eLife. They suggest that drugs used to lower inflammation in the lungs could prove beneficial to obese patients with the disease.

Tsukuba, Japan - Lymphomas are a diverse group of cancers of the immune system, which is the body's primary defense against autoimmune disease, infections, and malignancy. Now, researchers at the University of Tsukuba have clarified risk factors and molecular mechanisms underlying primary and adaptive resistance to cancer immunotherapy. This knowledge may inform treatment strategies against aggressive Non-Hodgkin lymphomas (NHL) including Burkitt lymphoma and diffuse large B-cell lymphoma.

The calcification of the carotid artery is a sign of advanced arteriosclerosis, which may be associated with chronic coronary artery disease (CAD) and can lead to death. Such calcification can be seen in regular oral panoramic radiography.

A collaborative study led by Monash University's Biomedicine Discovery Institute and the Olivia Newton-John Cancer Research Institute (ONJCRI) has uncovered new markers (HLA-associated peptides) that are uniquely present on melanoma tumours and could pave the way for therapeutic vaccines to be developed in the fight against melanoma.

Patients with a first-time depression diagnosis have an increased risk of the disease worsening and requiring hospitalisation, if they have previously been treated for a physical disease at a hospital. This is shown by research from iPSYCH.

Philadelphia, September 16, 2020 - The risk of developing major depressive disorder (MDD) surges during adolescence-particularly for girls. Cognitive behavioral therapy (CBT) can be an effective treatment, but only about half of girls diagnosed with depression show significant improvement. Researchers at Harvard Medical School and McLean Hospital have now identified a non-invasive test of brain function that could help predict who will respond to CBT.

A new study by researchers at the University of Illinois Chicago and the University of Pittsburgh suggests that a significant proportion of older patients receiving opioids at dental visits also use psychotropic medications -- a potentially harmful combination. Their findings are published in the journal Pharmacotherapy.

Debates over whether hydroxychloroquine should be taken to help lessen the duration and impact of COVID-19 have revolved around the drug's reputation for causing cardiac events such as abnormal heart rhythms or beats and cardiac arrest. Because of this, the U.S. Food and Drug Administration has revoked emergency use authorization for the drug in treating COVID-19.

Higher viral loads are associated with a greater risk of death among cancer and non-cancer patients hospitalized with coronavirus disease 2019 (COVID-19), researchers report September 15 in the journal Cancer Cell. Among hospitalized COVID-19 patients, those with hematologic malignancies who had recently been treated for cancer had the highest levels of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes COVID-19.

Researchers at Queen Mary University of London, The Institute of Cancer Research, London, and the Moffitt Cancer Centre have created a mathematical model that can determine the impact of the immune system on tumour evolution. The information gained from using this model may be able to be used to predict whether immunotherapy is likely to be effective for a patient's cancer, helping to guide treatment decisions.

A battle between cancer cells and immune cells

Ling Gao and colleagues have developed a strategy that uses exosomes - tiny membrane-bound sacs secreted by cells - to mimic the heart-regenerating effects of cardiac cell transplants, while potentially avoiding risks associated with whole-cell transplants. Their approach, which accelerated recovery from heart attack in pigs, could address issues with safety and effectiveness that have prevented whole-cell heart therapies from reaching clinical adoption.

Every time we eat, the glucose level in our body goes up. This spurs our pancreatic machinery into action and through intricate physiological mechanisms, appropriate amounts of insulin are produced, our blood glucose levels are controlled, and we remain healthy. But when a person indulges in high-fat food repeatedly over the long term, their pancreas is consistently overstimulated, eventually contributing to its damage and impairing its function. This increases the risk of developing type 2 diabetes, in which glucose level control mechanisms become lopsided.