Body

Macrophages are immune system cells. They are essential in the early response to infections, and they also have a key role in the proper functioning of our tissues and the regulation of obesity. Now, researchers at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have shown how this regulation unfolds in a paper published in Nature Metabolism, which could be useful to design new treatments for the obese and overweight, and for some associated pathologies, including fatty liver disease and type 2 diabetes.

Bottom Line: Proton pump inhibitor (PPI) use was associated with worse outcomes in patients with urothelial cancer treated with the immunotherapeutic atezolizumab (Tecentriq), compared with patients who did not use PPIs.

Journal in Which the Study was Published: Clinical Cancer Research, a journal of the American Association for Cancer Research

Author: Ashley Hopkins, PhD, an early-career research fellow at Flinders University in Australia

NEW YORK (September 17, 2020) -- All healthcare personnel should be immunized against vaccine preventable diseases recommended by U.S. Centers for Disease Control and Prevention's Advisory Committee on Immunization Practices (CDC/ACIP) as a condition of employment, according to a new policy statement by the Society for Healthcare Epidemiology of America.

Only about 54% of medical practitioners surveyed say they have prescribed pre-exposure prophylaxis, or PrEP, to HIV-vulnerable patients, according to a new study by a Vanderbilt University Medical Center investigator.

The study, led by Ashley Leech, PhD, assistant professor of Health Policy, surveyed 519 practitioners in five major U.S. cities who attended a continuing medical education course on HIV between March and May 2015. The study was published in PLOS ONE.

Researchers at Uppsala University have developed a new method to determine - rapidly, easily and cheaply - how effective two antibiotics combined can be in stopping bacterial growth. The new method is simple for laboratories to use and can provide greater scope for customising treatment of bacterial infections. The study is published in PLOS Biology.

Early in the onset of the COVID-19 pandemic, a small study in China produced results that influenced subsequent research on the virus. Researchers at the University of Cincinnati used the same study parameters on a much larger patient population and reached completely different findings. The study was published in the journal Progress in Cardiovascular Diseases in mid-July.

Reston, VA--A single-center observational study of more than 1,000 oncological examinations has demonstrated that positron emission tomography/magnetic resonance imaging (PET/MRI) facilitates cancer staging as well as PET/computed tomography (PET/CT) and improves lesion detectability in select cancers, potentially helping to promote fast, efficient local and whole-body staging in one step.

Consuming high fructose corn syrup appears to be as bad for your health as consuming sugar in the form of fructose alone, according to a new study from researchers at the University of California, Davis. The study reports health risks related to the type of sugar consumed, but also reveals novel risks when sugars are combined, which has important implications for dietary guidelines.

WINSTON-SALEM, N.C. -- September 17, 2020 -- For people with chronic insomnia, a good night's sleep is elusive. But what if insomnia symptoms could be alleviated by simply listening to one's own brainwaves?

Researchers at Wake Forest Baptist Health conducted a clinical trial that showed reduced insomnia symptoms and improved autonomic nervous system function using a closed-loop, acoustic stimulation neurotechnology. The study is published in the September 17 online edition of the journal Brain and Behavior.

PITTSBURGH, Sept. 17, 2020 - A blood protein test could detect the severity of head trauma in under 15 minutes, according to research published recently in the Journal of Neurotrauma.

ATLANTA - September 17, 2020 - A new report examining cancer in adolescents and young adults (AYAs), defined as diagnoses occurring during ages 15 to 39, provides updated estimates of the contemporary cancer burden in this age group, predicting that 89,500 cases and 9,270 deaths will occur in 2020 in the United States. The report appears in the American Cancer Society journal: CA: A Cancer Journal for Clinicians.

According to a recently published study of Finnish twins, smoking most likely causes a significant share of all cases of subarachnoid haemorrhage, the most fatal type of cerebrovascular disturbances. In the study, smoking was identified as the explanation as to why only one twin in pairs of twins develops a fatal brain haemorrhage. The finding is the first proof of an actual causality between smoking and subarachnoid haemorrhage.

DALLAS, September 17, 2020 -- An investigation of the Finnish Twin Cohort reaffirmed a link between smoking and subarachnoid hemorrhage (SAH), a type of bleeding stroke that occurs under the membrane that covers the brain and is frequently fatal. The new study by researchers in Finland is published today in Stroke, a journal of the American Stroke Association, a division of the American Heart Association.