Body

BOSTON - Every year, more than 330,000 people are diagnosed with kidney cancer worldwide. More than 80 percent of those new cases are renal cell carcinomas (RCC). When caught early, the five-year survival rate is more than 90 percent. Patients diagnosed with more invasive tumors, however, have dramatically poorer prognoses, with five-year survival rates of 50 percent and 10 percent for patients diagnosed at stages III and IV respectively. Early detection could improve the overall survival rate in patients at high risk for death from RCC.

GALVESTON, Texas - A new study from The University of Texas Medical Branch at Galveston has uncovered why some people that have brain markers of Alzheimer's never develop the classic dementia that others do. The study is now available in the Journal of Alzheimer's Disease.

Peer-reviewed / Observational study / People

-- Low-carb diets that replace carbohydrates with proteins and fats from plant sources associated with lower risk of mortality compared to those that replace carbohydrates with proteins and fat from animal sources.

Eating carbohydrates in moderation seems to be optimal for health and longevity, suggests new research published in The Lancet Public Health journal.

A blood test conducted as early as the 10th week of pregnancy may help identify women at risk for gestational diabetes, a pregnancy-related condition that poses potentially serious health risks for mothers and infants, according to researchers at the National Institutes of Health and other institutions. The study appears in Scientific Reports.

Fragility fractures are a serious yet neglected complication of both type 1 and type 2 diabetes, with increased risk of fragility fractures in people with diabetes extending across the life span.

This is a concern as, globally, the prevalence of diabetes in adults is expected to increase from almost 425 million today, to approximately 629 million by 2045. At the same time, many clinicians who treat patients with diabetes are not aware of their patients' heightened risk of disabling and potentially life-threatening fractures.

MINNEAPOLIS - The eyes may be a window to the brain for people with early Parkinson's disease. People with the disease gradually lose brain cells that produce dopamine, a substance that helps control movement. Now a new study has found that the thinning of the retina, the lining of nerve cells in the back of the eye, is linked to the loss of such brain cells. The study is published in the August 15, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology.

The ongoing opioid epidemic in the United States is a key contributor to the most recent declines in life expectancy, suggests a study published by The BMJ today.

A second study shows an increase in US death rates in midlife (people aged between 25-64 years) involving all major racial groups, and cites a broad range of conditions as potential causes.

Together, these findings point to an urgent need to examine systemic causes of declining health in the US.

Ann Arbor, August 16, 2018 - A study published in the American Journal of Preventive Medicine found that more than 50 percent of people with assault-related or legal intervention (LI) firearm injuries due to law enforcement actions and over 25 percent of individuals with self-inflicted or unintentional firearm injuries were arrested, hospitalized, or both in the two years prior to being shot.

A study of more than 1 million pregnancies in Finland reports that elevated levels of a metabolite of the banned insecticide DDT in the blood of pregnant women are linked to increased risk for autism in the offspring. An international research team led by investigators at Columbia University's Mailman School of Public Health and the Department of Psychiatry published these results in the American Journal of Psychiatry.

PHILADELPHIA--Parkinson's disease affects more than 4 million people worldwide, with numbers projected to double in the next few decades. With no known cure, there is a race for treatments to slow or stop the progression of the disease. Key to the research and discovery of treatments for Parkinson's is the identification of biomarkers--a measureable biological indicator, such as proteins found in blood, which can help diagnose disease.