ATS 2021, New York, NY - Individuals with asthma who live in redlined neighborhoods have worse lung function than those in locales that excluded Black people and benefited from decades of inequitable wealth accumulation at the expense of Black communities in the United States, according to research presented at the ATS 2021 International Conference.

Session: TP91

Abstract Presentation Time: On Demand; 8 a.m. EDT, Friday, May 14, 2021

ATS 2021, New York, NY - Having genetic risk variants in the ABO gene might significantly increase the chances of developing COVID-19, and other genes may also increase COVID-19 risk, according to research presented at the ATS 2021 International Conference.

The COVID-19 pandemic has been shown to have caused a significant strain on the healthcare system and resources in the United States. However, data regarding the impact of the virus on hip fractures, primarily seen in elderly patients, is lacking.

Interim results of a study conducted by researchers at Hospital for Special Surgery (HSS) suggest that oral tranexamic acid (TXA) is non-inferior to intravenous (IV) TXA in preventing blood loss in total knee and total hip replacement surgery. These findings were presented at the 2021 Spring American Society of Regional Anesthesia and Pain Medicine (ASRA) Annual Meeting.1

Scientists at UCL have identified a new immunotherapy to combat the hepatitis B virus (HBV), the most common cause of liver cancer in the world.

Each year, globally, chronic HBV causes an estimated 880,000 deaths from liver cirrhosis and hepatocellular carcinoma/liver cancer (HCC).

The pioneering study used immune cells isolated directly from patient liver and tumour tissue, to show that targeting acyl-CoA:cholesterol acyltransferase (ACAT), an enzyme that helps to manage cholesterol levels in cells*, was highly effective at boosting immune responses.

While it has been said that the eyes are a window to the soul, a new study shows they could be a means for understanding diseases of the brain. According to new research by scientists at the UCSF Weill Institute for Neurosciences, retinal scans can detect key changes in blood vessels that may provide an early sign of Alzheimer's, while offering important insights into how one of the most common Alzheimer's risk genes contributes to the disease.

Researchers at UC San Francisco have observed a new feature of neural activity in the hippocampus - the brain's memory hub - that may explain how this vital brain region combines a diverse range of inputs into a multi-layered memories that can later be recalled.

The protein made by the ASH1L gene plays a key role in the development of acute leukemia, along with other diseases. The ASH1L protein, however, has been challenging to target therapeutically.

Now a team of researchers led by Jolanta Grembecka, Ph.D., and Tomasz Cierpicki, Ph.D., from the University of Michigan has developed first-in-class small molecules to inhibit ASH1L's SET domain -- preventing critical molecular interactions in the development and progression of leukemia.

A new study with zebrafish shows that a deadly form of skin cancer -- melanoma -- alters the metabolism of healthy tissues elsewhere in the body. The research from Washington University in St. Louis suggests that these other tissues could potentially be targeted to help treat cancer.

Epidemic. Pandemic. These terms have become second nature to us, popping up in everyday conversation, and for good reason -- COVID-19 is the latest pandemic to pose a threat to humanity.

But in recent months, far less attention has been paid to another widely spread problem that has been proliferating since the late 1970s: Lyme disease.

PASADENA, Calif. -- Among cancer patients with health coverage in Southern California, those who were diagnosed and treated at Kaiser Permanente, an integrated health care organization, had better survival rates, especially Black and Latino patients, according to Kaiser Permanente research published in The American Journal of Managed Care.

The majority of children infected with SARS-CoV-2 may not show typical symptoms such as fever, cough or shortness of breath, according to a study published in Scientific Reports, which examined data on 12,306 children with laboratory-confirmed COVID-19 across the United States.

CHICAGO --- For men physicians, the professional perks of networking on social media, like being asked to give a talk, are abundant, a new Northwestern Medicine study reports.

For women physicians, the benefits are far less plentiful, the study found.

What's more, women physicians are more than twice as likely to be sexually harassed on social media than men physicians, according to an earlier study, published in January, of this same group of study participants.

Multiple studies have shown that African American women with breast cancer have lower survival rates than white women with the disease. But the association between race or ethnicity and treatment outcomes in triple-negative breast cancer -- an aggressive type of tumor that does not respond to hormonal or other targeted therapies -- has not been well defined.

Researchers at Hospital for Special Surgery (HSS) have identified gaps in patient knowledge about pain management and opioid use before total hip replacement, including misconceptions about how much pain relief to expect from opioids after surgery, how to use multiple modes of pain relief (multimodal analgesia) safely and effectively, and proper opioid storage and disposal. These findings were presented at the 2021 Spring American Society of Regional Anesthesia and Pain Medicine (ASRA) Annual Meeting.1