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ROCHESTER, Minn. -- Web-based analytics have demonstrated their value in predicting the spread of infectious disease, and a new study from Mayo Clinic indicates the value of analyzing Google web searches for keywords related to COVID-19.

Strong correlations were found between keyword searches on the internet search engine Google Trends and COVID-19 outbreaks in parts of the U.S., according to a study published in Mayo Clinic Proceedings. These correlations were observed up to 16 days prior to the first reported cases in some states.

Volume XX, Issue XX from @Oncotarget reported that TQ decreased the expression levels of colorectal stem cell markers CD44 and Epithelial Cell Adhesion Molecule Ep CAM and proliferation marker Ki67 in colonospheres derived from both cell lines and reduced cellular migration and invasion.

Altogether, the research team's findings document TQs effect on colorectal cancer stem-like cells and provide insights into its underlying mechanism of action.

WEST LAFAYETTE, Ind. - Scientists estimate that nearly 60% of all cancer patients do not respond effectively to chemotherapy treatments. Even worse - many of those same patients experience toxic and sometimes deadly side effects.

Now, a Purdue University scientist and entrepreneur is working to use simple LED light to help determine if certain chemotherapy options will work for specific patients. The work is published in Scientific Reports.

Non-Cancerous Tissue from Nephrectomy Specimens: A Window into Kidney Pathology

WASHINGTON--Patients with COVID-19 and vertebral fractures are twice as likely to die from the disease, according to a study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

Low levels of key, body-regulating chemicals in mothers during the first three months of pregnancy may interfere with the baby's brain development, a large American study shows.

These chemicals, or hormones, are produced in the thyroid gland in the neck and are known to influence fetal growth. Investigators have suspected that disruptions in their production, or hypothyroidism, may contribute to attention deficit/hyperactivity disorder (ADHD), which is the most common neurodevelopmental disorder of children in the U.S.

People who consume a diet including flavanol-rich foods and drinks, including tea, apples and berries, could lead to lower blood pressure, according to the first study using objective measures of thousands of UK residents' diet.

CLEVELAND--Brain cell dysfunction in low oxygen is, surprisingly, caused by the very same responder system that is intended to be protective, according to a new published study by a team of researchers at the Case Western Reserve University School of Medicine.

DALLAS, October 21, 2020 --The recovery phase following cardiac arrest continues long after hospitalization and is now included as a key link in the Chain of Survival, a widely adopted series of critical actions that work to maximize the chance of someone surviving cardiac arrest, according to the "2020 American Heart Association Guidelines for Cardiopulmonary Resuscitation (CPR) and Emergency Cardiovascular Care," published today in the Association's flagship journal, Circulation.

Bottom Line: Among women participating in cervical cancer screening in Sweden, those with a diagnosis of invasive cervical cancer had an increased risk of iatrogenic injuries (as a consequence of medical intervention) and non-iatrogenic injuries (caused by accidents and self-harm) requiring hospitalization.

Journal in Which the Study was Published: Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research

CHAPEL HILL, NC - October 21, 2020 - Babies born with a faulty maternal copy of the UBE3A gene will develop Angelman syndrome, a severe neurodevelopmental disorder with no cure and limited treatments. Now, for the first time, scientists at the UNC School of Medicine show that gene editing and gene therapy techniques can be used to restore UBE3A in human neuron cultures and treat deficits in an animal model of Angelman syndrome.

Opioid use disorder affects about 2 million Americans each year and is the No. 1 cause of accidental death. Between 50 to 90 percent of individuals with this disorder were exposed to a prescription opioid first. Opioid use disorder is likely underdiagnosed within the healthcare system setting, which may be due in part to the reticence of practitioners who lack the specialized training in addiction medicine.

A gut hormone, ghrelin, is a key regulator of new nerve cells in the adult brain, a Swansea-led research team has discovered. It could help pave the way for new drugs to treat dementia in patients with Parkinson's Disease.

Blood-borne factors such as hormones regulate the process of brain cell formation - known as neurogenesis - and cognition in adult mammals.

Although the diverse treatment methods developed to effectively treat cancer, chemotherapy using anticancer agents has been proven especially effective in many clinical applications. Above all, it is more affordable than other treatment methods and is effective against most types of cancer, which is why it is most common approach to treat disease.

ARLINGTON, Va., October 21, 2020 -- A new clinical guideline from the American Society for Radiation Oncology (ASTRO) provides guidance for physicians who use radiation therapy to treat patients with locally advanced rectal cancer. Recommendations outline indications and best practices for pelvic radiation treatments, as well as the integration of radiation with chemotherapy and surgery for stage II-III disease.