Body
A Rutgers-led team has created a smart drug delivery system that reduces inflammation in damaged nervous tissues and may help treat spinal cord injuries and other neurological disorders.
The system, which uses extremely thin biomaterials implanted in the body, also protects nerve fibers (axons) that connect nerve cells in injured neural tissues, according to a study in the journal Advanced Materials.
A collaborative study led by Monash University's Biomedicine Discovery Institute and the Olivia Newton-John Cancer Research Institute (ONJCRI) has uncovered new markers (HLA-associated peptides) that are uniquely present on melanoma tumours and could pave the way for therapeutic vaccines to be developed in the fight against melanoma.
Patients with a first-time depression diagnosis have an increased risk of the disease worsening and requiring hospitalisation, if they have previously been treated for a physical disease at a hospital. This is shown by research from iPSYCH.
The Government of India's use of nudge theory in the first three months of the pandemic helped to tackle the virus on numerous fronts, a new study suggests.
Debates over whether hydroxychloroquine should be taken to help lessen the duration and impact of COVID-19 have revolved around the drug's reputation for causing cardiac events such as abnormal heart rhythms or beats and cardiac arrest. Because of this, the U.S. Food and Drug Administration has revoked emergency use authorization for the drug in treating COVID-19.
University of Guelph researchers are the first to discover that adolescents react differently to e-cigarette vapour than adults.
Led by Prof. Jibran Khokhar, Department of Biomedical Science in U of G's Ontario Veterinary College, the rodent-based research measured behavioural responses related to vaping.
"This is the first study to show that rodents find e-cigarette vapour rewarding in a conditioned place preference experiment," Khokhar said,?referring to animals' preference for a chamber in which experimenters previously exposed them to a drug.
When viruses, parasites and other pathogens spread, humans and other animals tend to hunker down with immediate family and peer groups to avoid outsiders as much as possible. But could these instincts, developed to protect us from illnesses, generalize into avoidance of healthy individuals who simply look, speak or live differently?
Jessica Stephenson, an assistant professor in the University of Pittsburgh Department of Biological Sciences, coauthored a paper exploring the answer, which was recently published in the Proceedings of the Royal Society of London, Series B.
In the first week of the coronavirus pandemic, people living in the United States underestimated their chances of catching the virus, or of getting seriously ill from the virus, according to a recently published Caltech-led study. But as the days progressed, those same people became more worried about their personal risk, and, as a result, began to increase protective behaviors such as washing hands and social distancing.
New Rochelle, NY, September 16, 2020—Intracranial abnormalities on CT scan in patients with traumatic brain injury (TBI) can be predicted by glial fibrillary acidic protein (GFAP) levels in the blood. These interim findings from the TRACK-TBI study are published in the peer-reviewed Journal of Neurotrauma. Click here to read the article now.
DALLAS, Sept. 16, 2020 -- Heart transplant patients who received hearts from severely obese donors had similar short-term outcomes and long-term survival as patients who received hearts from non-obese donors, according to new research published today in Circulation: Heart Failure, an American Heart Association journal.
DALLAS, Sept. 16, 2020 -- Better heart health, as measured by the American Heart Association's Life's Simple 7 (LS7) scale, was associated with a significantly lower risk of developing high blood pressure (also known as hypertension) in middle-aged, Black and white adults, according to new research published today in the Journal of the American Heart Association, an open access journal of the American Heart Association.
Hennigsdorf/ Berlin, Germany, September 16, 2020 - 4TEEN4 Pharmaceuticals GmbH ("4TEEN4") announces data on the efficacy of its lead product, Procizumab, that promptly restored cardiac dysfunction in a preclinical sepsis model by inhibiting the cardiac depressant factor DPP3. The current findings indicate that DPP3 plays an important role in septic cardiomyopathy. Sepsis is a dysregulated host response to an infection that ultimately leads to organ dysfunction.
PITTSBURGH, Sept. 16, 2020 - The slight decline in drug overdose deaths in 2018 coincided with changing Chinese regulations on a powerful type of opioid, rather than the result of U.S. efforts to curb the overdose epidemic, a University of Pittsburgh Graduate School of Public Health analysis revealed today in the journal Addiction.
The SARS-CoV-2 pandemic has put the use of personal protective equipment (PPE), including face masks, under the global spotlight. However a paper published in Anaesthesia (a journal of the Association of Anaesthetists) reveals that masks do not always fit correctly and hospitals can lack the time and financial resources to ensure every healthcare worker has a mask that fits correctly.
The tool, available online, is the first of its kind and was developed and validated using anonymised data from around 120,000 sepsis patients from the ICNARC national database for critical care units across England.
The new tool is particularly timely as both survivors of sepsis and COVID-19 have risks of complications or death after leaving hospital and because the winter months are associated with an increase in sepsis admissions to hospital. The free, online tool could help inform patient care pathways to prevent unplanned readmissions to hospital and excess deaths.