Body

Medical experts have worked for decades to improve the chances that patients will get the scans, routine tests and medicines that can do them the most good - and avoid the ones that won't help them at all.

But in the push toward evidence-based medicine, a new study says, a key step has mostly gotten overlooked: helping doctors stop or scale back - or deintensify - treatment once it has started, and take the screening, testing and treatment down a notch as evidence changes or the patient's health, age and lifestyle change.

NEW YORK (September 14, 2020) -- Neonatal intensive care units (NICU) should balance prevention of Staphylococcus aureus infections in critically ill infants with the need for skin-to-skin contact with parents and siblings, according to a Society for Healthcare Epidemiology of America (SHEA) white paper published in the journal Infection Control & Hospital Epidemiology.

Thermography has been a hot topic this year, due to the need for quicker diagnostics to detect and prevent the spread of COVID-19. Noncontact infrared thermometers (NCITs) are currently a primary tool for fever screening, but their widespread use has been prone to inaccuracy. A related medical technology, thermography using infrared thermographs (IRTs), enables increased options for temperature estimation with greater accuracy.

ITHACA, N.Y. - Posted on Facebook, milestones such as birthdays and anniversaries prompt users to reflect on the passage of time and the patterns of their lives - and help the social media giant recycle content in order to boost engagement, according to new Cornell research.

And although these anniversaries seem like a signature product of the social media age, they stem from newspapers' tradition of printing historical events that happened "on this date," said Lee Humphreys, associate professor of communication in the College of Agriculture and Life Sciences.

The United States has seen a 200% increase in the rate of deaths by opioid overdose in the last 20 years. But many of these deaths were preventable. Naloxone, also called Narcan, is a prescription drug that reverses opioid overdoses, and in more than 40 states -- including Pennsylvania -- there is a standing order policy, which makes it available to anyone, without an individual prescription from a healthcare provider.

Launching a dual-pronged attack on tumours using a combination of two innovative precision medicines could treat patients with multiple common cancers, a new clinical trial shows.

It is the first trial to use the pioneering genetically targeted drug olaparib - already licensed for ovarian, breast and prostate cancer - together with a promising new medicine, called capivasertib.

Staying close to home and avoiding crowded places can help older adults reduce their risk of COVID-19. But a new national poll suggests it comes with a cost, especially for those with health challenges.

Why does exercise training make you more fit? It's well established that exercising enhances insulin sensitivity and improves our metabolism that, in turn, increases exercise performance. But the biological mechanisms underlying this adaptation are not fully understood.

Following a large-scale clinical trial, researchers have found that lanthanum carbonate does not reduce the risk of cardiovascular disease developing in patients with chronic kidney disease.

The drug is routinely prescribed to patients with chronic kidney disease to help reduce the risk of both bone disease and cardiovascular disease, with cardiovascular disease the most common complication and cause of death for this group.

A geneticist from RUDN University studied the effect of Bifidobacterium (intestinal bacteria) on the inflammatory process and discovered that their surface protein is capable of stopping excessive or uncontrollable inflammation, like the one observed in COVID-19 patients. A fragment of this protein can be used as an anti-inflammatory medication when treating coronavirus and other diseases. The results of the study were published in the Anaerobe journal.

Tokyo, Japan -- Patches seem to be all the rage these days. There are birth control patches, nicotine patches, and transdermal medicinal patches, just to name a few. Now, a team of researchers led by Beomjoon Kim at the Institute of Industrial Science, The University of Tokyo have developed a patch of needles connected to a paper sensor for diagnosing conditions such as prediabetes. Luckily, this patch doesn't multiply the pain and discomfort of a single hypodermic needle. In fact, these microneedles are painless and biodegradable.

SALT LAKE CITY - Newly published research has reversed our understanding of an aspect of kidney tumor growth. Researchers at Huntsman Cancer Institute (HCI) at the University of Utah (U of U) discovered that two key proteins have opposite roles than what was previously believed. The proteins HIF-1α and HIF-2α regulate the response to regions of low oxygen (hypoxia) in a solid tumor. Hypoxia is known to increase the aggressiveness of tumors, which is caused by the activation of the hypoxia inducible factor (HIF) proteins.

Researchers from The University of Texas Medical Branch at Galveston have found that while the 30-day readmission rate for patients with chronic obstructive pulmonary disease has decreased, the mortality rate has increased.

The UTMB researchers analyzed data from a nationwide cohort of more than 4.5 million Medicare beneficiaries with COPD to learn more about the impact of a federal program designed to reduce the number of people needing hospitalization within the first 30 days after being released from the hospital for a COPD-related illness.

What The Study Did: This study investigated the use of cardiac magnetic resonance imaging in competitive college athletes who recovered from COVID-19 to detect myocardial inflammation that would identify high-risk athletes for return to competitive play.

Authors: Saurabh Rajpal, M.B.B.S., M.D., of Division of Ohio State University in Columbus, is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

Scientists at St. Jude Children's Research Hospital are investigating the inherited genetics of childhood leukemia and how particular gene variations can affect treatment outcomes. The research showed that an inherited variation in the GATA3 gene strongly influences early response to chemotherapy and is linked to relapse in children with acute lymphoblastic leukemia (ALL). The work was published as an advance online publication this week in the Journal of the National Cancer Institute.