Body
Boston - A new study led by Boston Medical Center researchers indicates a well-known biomarker that serves as a marker for earlier diagnosis of neurodegenerative diseases is now detectable in the eye. Neurofilament light chain, a protein previously detected in cerebrospinal fluid and blood that is being explored as a biomarker to detect neurodegeneration, has now been identified in the vitreous humor, or fluid within the eye.
Irvine, CA - September 21, 2020 - In a new University of California, Irvine-led study, researchers have discovered how regulatory T cells (Treg) are instrumental in limiting the damage caused to the spinal cord in diseases like multiple sclerosis (MS).
Published in the Proceedings of the National Academy of Sciences, the results of the study help explain how Treg cells prevent autoimmunity and dampen immune responses, specifically the negative effects of type 17 helper T cells (Th17) which are known to drive the progression of several autoimmune diseases.
Throughout her 38-year nursing career, Laurel Despins has progressed from a bedside nurse to a clinical nurse specialist and has worked in medical, surgical and cardiac intensive care units. She noticed diabetes is rarely referred to as a primary cause of death in itself, yet the disease is a leading contributor to deaths involving heart disease, stroke and cancer.
The suspension of fertility treatments due to the COVID-19 pandemic has had a variety of psychological impacts on women whose treatments were cancelled, but there are several protective factors that can be fostered to help in the future, according to a new study by Jennifer Gordon and Ashley Balsom of University of Regina, Canada, published 18 September in the open-access journal PLOS ONE.
New research presented at this year's annual meeting of the European Association for the Study of Diabetes (EASD), held online this year (21-25 September), shows that having type 1 diabetes (T1D) is associated with a 33% increase in the risk of falls compared with the general population, while having type 2 diabetes (T2D) is associated with a 19% increased risk of falls. The study is by Nicklas Rasmussen, Steno Diabetes Center and North Jutland Aalborg University Hospital, Aalborg, Denmark, and colleagues.
Study shows that rheumatoid arthritis is associated with a 23% increased risk of developing diabetes
A new study presented at this year's annual meeting of the European Association for the Study of Diabetes (EASD), held online this year, shows that rheumatoid arthritis (RA) is associated with a 23% increased risk of type 2 diabetes (T2D), and may indicate that both diseases are linked to the body's inflammatory response. The research was conducted by Zixing Tian and Dr Adrian Heald, University of Manchester, UK, and colleagues.
New research being presented at this year's Annual Meeting of the European Association for the Study of Diabetes (EASD), held online this year, shows that when one half of a couple shows high levels of certain behaviours that prevent type 2 diabetes, such as good diet or exercise, that behaviour also tends to be high in the other half of the couple. The study is by Omar Silverman-Retana, Department of Public Health, Aarhus University, Aarhus, Denmark, and Steno Diabetes Center Aarhus, Aarhus University Hospital, Aarhus, Denmark, and colleagues.
Results from the PROfound phase III study, funded by AstraZeneca and Merck Sharp & Dohme, open up a much-needed new treatment avenue for the more precise and effective treatment of patients with metastatic castration-resistant prostate cancer (mCRPC) whose disease has progressed with hormonal therapy.
The PROfound trial investigators show significantly longer overall survival of mCRPC patients with at least one alteration in BRCA1, BRCA2, or ATM genes, who received treatment with PARP inhibitor olaparib versus enzalutamide or abiraterone plus prednisone.
Lugano, Switzerland, 20 September 2020 - Adding abemaciclib to hormonal therapy reduces the risk of cancer recurrence by 25% in patients with high-risk early hormone receptor positive (HR+) human epidermal growth factor receptor 2 negative (HER2-) breast cancer, according to results from a study at ESMO 2020. (1)
A drug used to treat breast and ovarian cancer can extend the lives of some men with prostate cancer and should become a new standard treatment for the disease, concludes a major trial which is set to change clinical practice.
Final results from the trial showed that olaparib - a pioneering type of drug called a PARP inhibitor and the first ever cancer drug to target an inherited genetic fault - can be used successfully to treat prostate cancers with a weakness in their ability to repair damaged DNA.
New research suggests that Black women experience longer waits for treatment initiation than white women after a breast cancer diagnosis, and their duration of treatment is prolonged. The findings are published early online in Cancer, a peer-reviewed journal of the American Cancer Society (ACS).
Irvine, Calif. - Experiencing multiple stressors triggered by the COVID-19 pandemic - such as unemployment - and COVID-19-related media consumption are directly linked to rising acute stress and depressive symptoms across the U.S., according to a groundbreaking University of California, Irvine study.
The report appears in Science Advances, published by the American Association for the Advancement of Science.
Lugano, Switzerland, 19 September 2020 - The results of the phase 3 CheckMate 9ER trial have provided a new first-line treatment option for patients with metastatic kidney cancer. The late breaking results are presented at ESMO 2020. (1)
A deadly combination of two mosquito-borne viruses may be a trigger for stroke, new research published in the The Lancet Neurology has found.
Public health agencies need ethical guidelines for deciding what to do when anonymous student health surveys discover a very high local rate of suicide-risk, according to CU researchers.
In a report published today in the highly influential American Journal of Bioethics, the researchers describe a student health survey team that discovered a Colorado school with extremely high rates of suicide risk, and a lack of ethical guidance on whether or how to intervene.