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Immune Checkpoint Molecule Can Stop Cancer All By Itself

Feb 19 2019 - 11:02

An immune checkpoint molecule, SA-4-1BB developed for cancer immunotherapy also protects against future development of multiple types of cancer when administered by itself, shows a new study.

The recombinant protein molecule SA-4-1BBL has been used to enhance the therapeutic efficacy of cancer vaccines with success in pre-clinical animal models. It accomplishes this by boosting the effectiveness of CD8+ T cells, adaptive immune cells trained to target the tumor for destruction. When the researchers treated normal healthy mice with SA-4-1BBL alone, the mice were protected when the researchers later exposed them to different types of tumor cells.

Patrolling the body instead of generating an immune response after the tumor is present

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'Cellular Barcoding' Reveals How Breast Cancer Spreads

Feb 18 2019 - 16:02

Cellular barcoding has been used to tag, track and pinpoint cells responsible for the spread of breast cancer from the main tumor into the blood and other organs, and also revealed how chemotherapy temporarily shrinks the number of harmful cells, rather than eliminating them, explaining how the cancer could eventually relapse.

Pinpointing the 'seeders' of disease

Most deaths from breast cancer are caused by the metastasis, or spread, of cancerous cells from the main tumor site into other organs. 

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Paper Claims A Link Between Glyphosate And Cancer But Fails To Show Evidence

Feb 18 2019 - 12:02
A new analysis,which appeared in the journal Mutation Research, claims To show evidence linking exposure to the common weedkiller glyphosate to non-Hodgkin’s lymphoma (NHL), a rare form of cancer, but it provides no new data and is not what it presents itself to be.

Could exposure to glyphosate -- an herbicide often paired with genetically engineered corn, soybeans, cotton, and other crops – be causing cancer? That question has become the central contention advanced by critics of agricultural biotechnology.

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Women Wear White To Promote Equality - But Other Colors Were Historically Important Also

Feb 16 2019 - 09:02

During President Donald Trump’s Feb. 5 State of the Union address, scores of Democratic congresswomen wore white to pay tribute to suffragists and their fight for women’s rights.

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The Good News And Bad News Of Cannabis-Infused Drinks

Feb 15 2019 - 13:02
Former Denver Broncos running back Terrell Davis, who trained by running with tractor tires strapped to his waist and all that, has an easy marketing hook for his new cannabis 'athletic recovery' drink; if I am wrong, then why do I have two Super Bowl rings and a spot in the NFL Hall of Fame?(1) 

It sounds ridiculous when it's so on-the-nose, but that kind of strategy is common because it works. It is why athletes lend their name to products, and why friends of athletes want them involved in companies. As is happening with this Defy beverage, which touts that it contains cannabidiol (CBD) extracted from the marijuana and is being pushed by David, a friend of the CEO.

The bad news: there is no way this is an anti-inflammatory

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Statisticians Link Glyphosate To Greater Chance Of NHL Cancer In Meta-Analysis

Feb 14 2019 - 18:02
Exposure to glyphosate — at 45 years of age the world’s most widely used, broad-spectrum herbicide and the primary ingredient in the weedkiller Roundup — increases the risk of some cancers by more than 40 percent, according to a meta-analysis published in the online journal Mutation Research/Reviews in Mutation Research, an imprint of publishing giant Elsevier.

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Kids Running Lemonade Stands Understand The U-Shaped Curve Isn't Real, Why Don't Journalists?

Feb 14 2019 - 15:02
Friends of the Earth, the kooky offshoot of Sierra Club that hates science even more, is dumping its advertising budget into a claim it commissioned from a Maharishi Institute scholar who runs what is apparently an uncredentialed lab claiming they were able to detect a weedkiller in common food.

Any scientist could have told them that and saved their money.

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"Ultra-Processed" Food Is Not Killing People In France - Too Many Calories Are

Feb 13 2019 - 10:02
A recent paper in JAMA Internal Medicine had all of the ingredients mainstream media love in food stories; a cosmic sounding number of participants (44,551), which sounds like it adds statistical power, and a provocative conclusion about the perils of the modern world - in this case that eating "ultra-processed food" is lowering life expectancy.

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Raw Milk Linked To Possible Bacterial Infections In 19 States

Feb 12 2019 - 20:02
Raw milk sold by Miller’s Biodiversity Farm in Quarryville, Pennsylvania and laced with Brucella strain RB51 has been linked to exposures in 19 states by the U.S. Centers for Disease Control and Prevention.

Raw milk, a recent trend by organic food lovers, lacks pasteurization, a process created by Louis Pasteur that has saved millions of lives by removing harmful bacteria like RB51. A cow that tested positive for RB51 has been removed from the milking herd and after one case of infection was confirmed in New York in November 2018, there are concerns that an unknown number of people may have been infected due to the milk from this farm. 

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The Genetics Of Having Perfect Pitch

Feb 12 2019 - 14:02
Perfect pitch may be more strongly under genetic control than previously thought, according to a new study.

Mozart, Bach, and Beethoven were able to precisely identify musical notes and there is certainly a genetic component to music like there is math or sprinting - while anyone can be functional with practice being truly great may take biology. Perfect (absolute) pitch is rare, even among expert musicians, and the relative contribution of genetics and experience to this ability remains debated.

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This Is Your Brain On Love

Feb 12 2019 - 12:02

Is love a mystery or can it be reduced to chemical processes in the brain? And, what are those chemical processes? And, perhaps most importantly, can you prepare the brain for love?

Falling in Love

When you are falling in love a kind of chemical bomb goes off in the brain. There’s a chemical storm of dopamine and noradrenaline that makes you feel excited and warm all over.

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Oxytocin And Vasopressin - An Experiment Tackles The Chemistry Of Love And Altruism

Feb 12 2019 - 12:02
Love is a complex topic. You love your dog differently than you love chocolate. There are times when you might put your dog, or a loved one, ahead of yourself, but you would never jump in front of a moving car to save chocolate.

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New Research Does NOT Mean A World Without Insects

Feb 11 2019 - 21:02

Please don’t be scared by this, it is just the journalists hyping things up again. It does not mean what it seems to mean from the headlines. Insects can’t vanish and we will continue to be able to grow our crops and do agriculture. The study itself involves a lot of extrapolation on inadequate data, not their fault, it is just that there hasn’t been that much research done on insect populations for them to draw on. 73 studies is not a lot for the whole world and the studies are limited.

This is another example of hugely hyped up research with click bait headlines. Journalists do love a good “catastrophe” - this is generating terrifying headlines for the easily scared.

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Genesis In Space: Israel Is About To Be The Fourth Country To Have A Moon Mission

Feb 11 2019 - 16:02
A short few months after China became the third country with a moon mission (following the United States and the Union of Soviet Socialist Republics), Israel will be the fourth.

On February 22nd, 2019, give or take weather events, the Beresheet Moon lander, once one of the candidates for the Google Lunar X-Prize, will make Israel the fourth country with a moon mission. And its $100 million for planning and execution has been made possible through cooperation of private individuals, corporate and government groups, and academia. 

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L’Oréal Foundation / UNESCO announced laureates of the 21st International Awards For Women in Science

Feb 11 2019 - 14:02
The L’Oréal Foundation and UNESCO have announced the laureates of the 21

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After 25 Years Of Chaos, FDA Signals For Reform When It Comes To Supplement Oversight

Feb 11 2019 - 12:02
United States Food and Drug Administration Commissioner Scott Gottlieb, M.D., has been in the private sector and in government, he has been care provider and patient, he has used supplements and watched as a $40 billion supplements industry duped the gullible and often engaged in outright deception, all using an exemption granted by the U.S. government.
But a recent statement by him, coupled with a raft of warning letters to supplement companies, signals that might change.

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Lawyers Don't Always Win Against Doctors And Hospitals - Like In Facial Trauma Lawsuits

Feb 11 2019 - 10:02
Mention to doctors who run their own practice or a hospital administrator that malpractice and American tort culture are probably the biggest reason for high health care costs, they will likely correct you and say that it is instead defensive medicine - running tests and engaging in efforts a doctor knows are unnecessary or useless to check off boxes that will prevent a lawsuit if something ever does go wrong.

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Have You Appeared In A Racist Photo Or Harassed Women? Here's How To Say 'I'm Sorry'

Feb 09 2019 - 10:02

“I’m sorry.”

These two words may seem simple, but the ability to express them when you’re in the wrong is anything but – particularly for those in the public eye.

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Kratom Is A Drug, But Indonesia Really Wants It To Remain An Unlicensed Supplement

Feb 09 2019 - 09:02
A product like Zicam, which claims it can make colds shorter, shields itself from truth in advertising claims by admitting on the label its product is not actual medicine, it is homeopathy, a pretend drug for people who want to believe.

If they were required to show it works, the way pharmaceutical products must, they'd be out of business. If they could pass a double-blind clinical trial, or any homeopathic product could, they'd spend the money in a second, because every supplement that wants to be legitimized yearns for U.S. Food and Drug Administration legitimacy. FDA may have flaws, like all groups do, but it is the gold standard for the world. 

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