In late 2014 I came downstairs from my home office and said to my wife, "Herb London just left me a message."
"Is he any relation to Stacy London?" she asked in her offhand humor way. Well, yeah, she is his daughter, if you are from California, but if you are of my generation and from anywhere near the orbit of New York, you know who Herb London is. And Herb London was getting a return phone call.
The authors contend that climate change is already having an impact on species populations, including climate-related extinctions in recent years. The authors suggest that sperm function is an especially sensitive trait. Sperm function is essential for reproduction and population viability, and so they sound a warning that biodiversity is already collapsing.
A new analysis links urban planning decisions - the freeways and local schools outside cities that made the suburbs possible - from decades past as why right-wing populism exists.
They created their correlation by looking at voting trends up to 2010 in in the Toronto area and matched them to people moving out of the city. As the desire for a yard and a house increased, politicians began to consider people who want more comfort and convenience. And now a humanities scholar contends those people are now right-wing populists, in a creepy kind of left-wing frame, but the reason progressive demands for more "sustainability" have failed.
Tools to translate text between languages are widely available - and rather awful. While they can create literal translations, style is hard to bring across without human intervention. If you tried to read a translation of China's Liu Cixin using a computer, you would miss everything, most importantly a great example of the best science-fiction culture since America of the 1950s.
The Chair of the NRC, tasked with managing nuclear energy in America, hated nuclear energy? Yes and he still does, but despite that he got the job because, well, that's politics. President George W. Bush was a dealmaker and Senator Harry Reid wanted the Bush administration to ignore two decades of studies showing that America needed one modern nuclear waste storage facility, rather than over 100 that exist now, and the perfect place was under a mountain in Nevada, Reid's state.
Potatoes are native to South America and became an agricultural crop in the Andean highlands of what is now Peru. But wild tubers genetically modified into potatoes did something interesting in return; they altered the genomes of the Andeans who made it a staple of their diet. Co-evolution. This co-evolution between agriculture and human is evident in the configuration of a gene associated with starch digestion in the small intestine - MGAM - in the agricultural ancient Andean genome samples, but not in hunter-gatherers down the coast.
Companies have to have Phase III trials before they can get approval. Phase I proves safety and dosing while Phase II shows it is better than a placebo and Phase III is intended to show it either works better than existing treatments or has fewer side effects. That's all after numerical models and animal studies. Since FDA essentially doubled the costs to get drug approval in the early 2000s only the most promising drug advances to Phase III. perhaps 1 in 5,000 that look good on a computer. It simply isn't worth the cost otherwise.
What began as an expedition to record the inscriptions of ancient Egyptian quarry workers produced a remarkable discovery about the Great Pyramid at Giza. My colleagues and I in the Anglo-French joint archaeological mission to the ancient quarry site of Hatnub recently revealed the existence of a well-preserved haulage ramp dating to the time of the Great Pyramid, roughly 4,500 years ago.
But why? A new study says it has solved the mystery.
AMPK acts as a fuel gauge for the cell, overseeing energy input and output to keep the cell running smoothly. Similar to a car sensor flashing a low-gas signal or turning off a vehicle’s AC to save energy, AMPK slows down cell growth and changes the cell’s metabolism if the cell’s fuel (nutrients) is low.
Given the challenges in building such huge structures, it is no surprised the Great Pyramid of Khufu is one of the Seven Wonders of the Ancient World. It and others were built thanks to quarries connected to the Nile by Bronze Age roads. The blocks were transported by sleds. But what about construction? Huge ramps? Were they poured? Some even speculated about aliens.
Glycosides are essential enzymes to digest carbohydrates but they are also key players in infections caused by pathogens, in anti-bacterial defense and many other vital cellular processes. Because these small molecules that are able to bond with and inhibit the activity of enzymes in infectious diseases, it opens up the basis for new medicines.
Was Oumuamua A Solar Sail From An Alien Civilization That Flew Past Earth Last Year? Entertaining But Implausible Suggestion
Short summary: it's an entertaining but rather far fetched proposal in an arxiv preprint not published anywhere but mentioned in a Scientific American op ed. Implausible for many reasons including its spectrum which is not the shiny spectrum you'd expect from a solar sail but the red of tholins mixed with rock and metal as you'd expect from an asteroid / comet.
The midterm elections are widely expected to usher in this century’s “year of the woman” – an explosion of women entering government.
Massachusetts will likely elect its first black woman to Congress, Arizona is poised to send its first woman to the U.S. Senate, and fully 50 percent of Democratic congressional nominees this year are women.
Our feces is largely (75%) made up of water, although this differs from person to person.
One crucial question is “what makes some people crave alcohol in excess acutely ie a single sitting and/or chronically over time”? Scientists have long known that the answer involves the neurotransmitter dopamine in the ventral tegmental area (VTA) of the brain.
Recently Mark Brodie, Professor of Physiology and BioPhysics at the University of Illinois at Chicago published an interesting article in the journal Neuropharmacology. His research focused on the potassium channel KCNK13 which is found inside the membrane of dopaminergic neurons in the VTA.