Body

DENVER - The International Association for the Study of Lung Cancer (IASLC) created the 2016 consensus statement on optimizing management of epidermal growth factor receptor (EGFR) mutation positive (M+) non-small cell lung cancer (NSCLC) patients, published in the Journal of Thoracic Oncology (JTO), to discuss key pathologic, diagnostic, and therapeutic considerations.

You've injured your knee. A doctor straps a listening device to it, and the noises you hear coming out of it are cringe-worthy. "Crackle! Krglkrglkrgl! Snap!"

Your knee isn't breaking; it's only bending, and in the future, those sounds could help doctors determine whether the convalescing joint is healthy yet, or if it needs more therapy.

Research engineers at the Georgia Institute of Technology are developing a knee band with microphones and vibration sensors to listen to and measure the sounds inside the joint.

Chloride plays a key role in the formation of the basement membrane, a suprastructure on the outside of cells that undergirds and guides the function of most of the tissues of the body.

In particular, chloride signals the assembly of collagen IV "smart scaffolds," a critical step in basement membrane formation, researchers at Vanderbilt University Medical Center (VUMC) reported today in the Journal of Cell Biology.

COLUMBUS, Ohio - English ivy's natural glue might hold the key to new approaches to wound healing, stronger armor for the military and maybe even cosmetics with better staying power.

New research from The Ohio State University illuminates the tiny particles responsible for ivy's ability to latch on so tight to trees and buildings that it can withstand hurricanes and tornadoes. (Not to mention infuriate those trying to rid their homes of the vigorous green climber.)

A team led by Rice University bioengineering researchers has decoded the mechanism that some bacteria use to make life-or-death decisions during extremely tough times.

Deciphering how bacteria respond to stress could yield new clues for combating food spoilage and for controlling food-borne pathogens. The new study was published in Molecular Systems Biology and sheds light on a long-standing debate about one of the field's fundamental questions: What causes stressed-out bacteria to make the drastic move to cease normal functions and form spores?

(Boston)--While breast cancer is the most common cause of cancer death in women worldwide, ovarian cancer also is a significant source of mortality as the fifth leading cause of cancer death among women. These facts reflect the continued need for further understanding and innovation in cancer treatment.

A new study published in the International Journal of Molecular Sciences, describes a new concept of how these two cancers may evolve in a similar way and may eventually lead to more effective therapies for both.

A five-week obesity prevention program for seventh grade students in Southern California helped obese students lose weight over a long-term period, according to a new study from the RAND Corporation, Boston Children's Hospital, Harvard Medical School and the Los Angeles Unified School District.

The average reduction in body mass index (BMI) measured for obese students of average height two years later when they entered high school translated into about nine pounds lower bodyweight. The findings are published in the May issue of the journal Pediatrics.

Bottom Line: Whole-exome sequencing of both colorectal adenomas (precancers often called polyps) and intestinal mucosa at risk for developing into adenomas from patients with familial adenomatous polyposis (FAP) has generated a comprehensive picture of the genomic alterations that characterize the evolution of normal mucosa to precancer.

Journal in Which the Study was Published: Cancer Prevention Research, a journal of the American Association for Cancer Research.

Researchers at The University of Texas MD Anderson Cancer Center have discovered mutations that may fuel early cancer growth in precancerous colorectal tissue from high-risk patients.

Their study, published in Cancer Prevention Research, is the first to use advanced genetic sequencing techniques to characterize genetic changes in precancerous polyps and nearby tissue that has not yet transformed into polyps. In addition to mutations at very early stages of cancer development, the findings identify potential drug targets for colorectal cancer (CRC) prevention.

Major work led by Santiago Costantino (researcher, Hôpital de Maisonneuve-Rosemont and associate professor, Université de Montréal), Dr. Claudia Kleinman, investigator at the Lady Davis Institute at the Jewish General Hospital and Assistant Professor at McGill University, and a multidisciplinary team of collaborators, gives birth to a unique method that enables instant, specific labeling of individual cells, Cell Labelling via Photobleaching (CLaP). This method will become a precious ally in a wide range of scientific research, with particular applications for genomics.

Montreal (Quebec), May 24, 2016 - At age 70, Alfred Roberts plays hockey twice a week. Nothing special, right? Except that for three years he has had advanced prostate cancer, which has spread to his bones. "I've always been active. Hockey keeps me in shape and keeps my mind off things. I've got friends that have played until age 80, and my goal is to beat them!" said the veteran stick handler.

Barcelona, Spain: Obesity is on the rise throughout the world, and in some developed countries two-third of the adult population is either overweight or obese. This brings with it an increased risk of serious conditions such as heart disease, stroke, cancer and osteoarthritis. Many of these conditions do not appear to affect the parts of the body where the excess fat accumulates, but rather to involve body systems that are remote from the fat accumulation.

Barcelona, Spain: Colorectal cancer is the second most common cause of cancer-related deaths in the Western world, mainly because it is usually diagnosed too late. Finding ways to identify those people who are at increased risk of developing colon cancer is therefore crucial, a researcher will tell the annual conference of the European Society of Human Genetics today.

A pioneering team of international researchers have devised a 'manifesto for fire science' to explore the pivotal relationship that exists between mankind and fire, on a global stage.

The team, brought together by Dr Claire Belcher from the University of Exeter's wildFIRE Lab and colleagues, delves into the complex relationship that fire has had with our planet and humans over millennia, from the first fires through to its role in the industrial revolutions worldwide.

Population researchers have called on governments to collect and share more information about migration to keep better track of the millions of people who move from one country to another each year.

Record numbers of people have fled the ongoing conflict in Syria, bringing global attention to international migration.

Professor James Raymer from The Australian National University (ANU) said it was impossible to accurately determine how many people were moving and settling in new countries.