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Antidepressants commonly and increasingly prescribed for nondepressive indications

In a study appearing in the May 24/31 issue of JAMA, Jenna Wong, M.Sc., of McGill University, Montreal, Canada, and colleagues analyzed treatment indications for antidepressants and assessed trends in antidepressant prescribing for depression.

Rates of obesity, diabetes lower in neighborhoods that are more walkable

Urban neighborhoods in Ontario, Canada, that were characterized by more walkable design were associated with decreased prevalence of overweight and obesity and decreased incidence of diabetes between 2001 and 2012, according to a study appearing in the May 24/31 issue of JAMA.

Research points to possible new prevention strategies for ovarian cancer

The discovery of early changes in the cells of the Fallopian tubes of women carrying the BRCA genetic mutation could open the way for new preventative strategies for ovarian cancer, reducing the need for invasive surgery, according to research published today in science journal Nature Communications.

New Joint European Cardiovascular Prevention Guidelines launched today

The highly anticipated document gives the latest advice on prevention of cardiovascular disease (CVD) in individuals and populations. It is published in European Heart Journal,1 the European Journal of Preventive Cardiology and other specialty journals, and presented in a dedicated session at Heart Failure 2016 and the 3rd World Congress on Acute Heart Failure in Florence, Italy.2

How much can a mode-2 wave move?

WASHINGTON, D.C., May 24, 2016 -- Look out over the ocean and you might get the impression that it's a mass of water acting as a single entity. However, the world's oceans are made up of layers of different densities, called stratifications, with complex fluid dynamics. Often bulges, called mode-2 internal waves, form in the thickness of these layers, trapping materials inside that then move along with the wave. For the first time, two mathematicians at Canada's University of Waterloo have created a 3-D simulation of the mass transport capabilities of mode-2 waves.

Rutgers scientists help create world's largest coral gene database

Coral reefs - stunning, critical habitats for an enormous array of prized fish and other species - have survived five major extinction events over the last 250 million years.

Study documents African monkeys eating bats

Although Cercopithecus monkeys, a widely distributed genus in Africa, usually have a discerning palate for fruits and leaves, they are opportunistic omnivores that sometimes consume lizards, snakes, birds and mice. These forest-dwelling primates share habitat and food resources with bats, which are known reservoirs for zoonotic diseases such as Ebola, Marburg and Henipa viruses as well as bacteria and parasites that can be spread between animals and humans.

Targeted treatment for liver cancer under way

Researchers at the University of Eastern Finland and Eberhard Karls Universität Tübingen have discovered a new molecular mechanism that can be used to inhibit the growth of hepatocellular carcinoma, which is the most common liver cancer. The findings were published in Nature Medicine.

New tools to manipulate biology

Chemistry has provided many key tools and techniques to the biological community in the last twenty years. We can now make proteins that Mother Nature never thought of, image unique parts of live cells and even see cells in live animals. This week in ACS Central Science, three independent research groups from the University of Geneva (UNIGE) and one from the University of Basel (UNIBAS) take these accomplishments a step further, reporting advances in both how proteins are made and how you can see their expression patterns in live animals.

Clue for efficient usage of low-cost nickel catalysts

A group of researchers at Osaka University developed a method of the consecutive formation of bonds of two butadiene, alkyl groups, and benzene rings by using a cheap nickel catalyst. Using this technique, it has become possible to synthesize high-value terminal olefin by using cheap butadiene.

Multicomponent reactions are methods which are superior in economy and efficiency to methods of bonding molecules by repeating reactions, but it was necessary to control the number of molecules to be bonded and locations of the bonds, so their applications were limited.

May repairs full of mistakes develop into cancer?

A group of researchers at Osaka University found that if DNA damage response (DDR) does not work when DNA is damaged by radiation, proteins which should be removed remain instead, and a loss of genetic information can be incited, which, when repaired incorrectly, will lead to the tumor formation.

Vitamin A may help improve pancreatic cancer chemotherapy

Around 8,800 people in the UK are diagnosed with pancreatic cancer each year. It is known as the UK's deadliest cancer, with a survival rate of just 3 per cent. Chemotherapy and radiotherapy alone are relatively unsuccessful in treating the disease, and while surgery to remove the tumour offers the best chance of survival, most patients are diagnosed when the cancer has already spread to other organs. A different approach is therefore needed to target the cancer more effectively.

Nonprofit exec turnover more turbulent than previously thought

New research from North Carolina State University finds that turnover among executive leaders at nonprofit organizations is often plagued by problems - with very few transitional periods mirroring the scenarios painted in the professional literature. The study also found that most nonprofit executives do not leave their positions due to voluntary retirement, as previously thought.

Study of fungi-insect relationships may lead to new evolutionary discoveries

Zombie ants are only one of the fungi-insect relationships studied by a team of Penn State biologists in a newly compiled database of insect fungi interactions.

"I couldn't find a place with broad information about all groups of fungi that infect insects in the same study," said Joao Araujo, graduate student in biology. "When we organized the information, we started to understand things we wouldn't see before, because the literature was so spread."

Babies fed directly from breast may be at less risk for ear infections

Feeding at the breast may be healthier than feeding pumped milk from a bottle for reducing the risk of ear infection, and feeding breast milk compared with formula may reduce the risk of diarrhea, according to a recent study by researchers at The Research Institute at Nationwide Children's Hospital.