The stem cells tasked with creating and maintaining biological tissues have a difficult job. They have to precisely divide to form new specialized cells, which are destined to different fates even though they contain identical DNA. An obvious question then is: How do the cells divide in all the right ways to produce a healthy tissue? This was the grand motivating question for Andrew Muroyama, a postdoctoral scholar in the lab of Stanford University biologist Dominique Bergmann, as he monitored days of leaf development in the flowering plant Arabidopsis thaliana.
BOSTON - Scientists at the Massachusetts General Hospital (MGH) have developed a molecular imaging probe to reveal Alzheimer's disease (AD)-related γ-secretase in rodents and macaques with translational potentials in humans. γ-Secretase is a key player in the etiology of AD and a prime drug target for AD, whose brain regional expression and distribution have yet remain largely unknown. This study describes the development of a molecular imaging probe to reveal γ-secretase in rodents and macaques with translational potentials in humans.
Children who experience neglect are seven times more likely than other abuse victims to have a teen pregnancy say University of Queensland researchers.
A study of the long-term impact of child abuse and neglect found that neglect was one of the most severe types of maltreatment when compared to emotional, sexual and physical abuse.
"You have to eat!" It's a sentiment that illustrates how central food is to Italian culture, but the woman who uttered these words also happens to be struggling with bulimia nervosa.
Carmela* is one of many Italian-Australian women who has a conflicted relationship with food which is inextricably linked to culture, according to University of South Australia researcher Michelle Caruso.
The social work PhD student has undertaken the first study looking at how Italian culture can influence women's experiences of disordered eating in contemporary Australia.
Humans, like other animals, have the ability to constantly adapt to new situations. Researchers at the Brain Research Institute of the University of Zurich have utilized a mouse model to reveal which neurons in the brain are in command in guiding adaptive behavior. Their new study contributes to our understanding of decision-making processes in healthy and infirm people.
The alcohol industry is increasingly funding academic research into the impacts of alcohol consumption - with some studies making claims about the health benefits of alcohol, new research suggests.
The study found that since 2009, there has been a 56% increase in research funded by alcohol companies or affiliated organisations.
The scale of alcohol industry sponsorship of scientific research raises concerns over the potential for bias, conflicts of interest and selective reporting of outcomes, the researchers say.
PITTSBURGH, Sept. 16, 2020 - People with one of the most common heart disorders who are exposed to greater levels of pollution have a 1.2-fold higher risk of stroke than their peers who live with less pollution, according to a JAMA Network Open study published recently by researchers at the UPMC Heart and Vascular Institute and University of Pittsburgh School of Medicine.
Building materials with a clear composition and stable structure is one of the primary challenges in chemistry and cluster science. Ongoing extensive efforts have been paid to exploring new stable clusters thus to construct new materials and to understand structural evolution bridging atoms and macroscopic matter. This is interesting yet challenging in chemistry. In the past decades, researchers have achieved significant advances, such as the discovery of fullerene C60, tetrahedral Au20, and all-boron fullerene B40, etc.
Overall, scientists from 24 countries and regions contributed, including the United Kingdom, Saudi Arabia, the Netherlands, the United States, Greece, Germany, Brazil, Pakistan, Malaysia, Australia, Argentina, Georgia, Romania, Armenia, Chile, China (with Hong Kong as a separate participant), Turkey, Italy, and Mexico. Overall, 5,320 students have been polled. Associate Professor of the KFU's Department of Pedagogical Psychology Olga Lopukhova was one of the participants.
When we talk of Nordic history, it is all but impossible not to mention the Vikings. Stories about the Scandinavian warriors and their Old Norse Gods have long since travelled all around the world. But perhaps part of that narrative is only based on myths and brought to life by popular culture. At least, this is what is indicated by a new study from the University of Copenhagen.
Researchers at Trinity College Dublin have examined the sustainability of different models of the most commonly used oral health product - the toothbrush - to ascertain which is best for the planet and associated human health.
The Government of India's use of nudge theory in the first three months of the pandemic helped to tackle the virus on numerous fronts, a new study suggests.
In response to the COVID-19 pandemic, public transport agencies across North America have made significant adjustments to services, including cutting trip frequency in many areas while increasing it in others. In many cases, these changes, especially service cuts, have disproportionately affected areas where lower-income and more vulnerable groups live, according to a new study from McGill University.
The most basic activity of a living thing is to turn one copy of its genome into two copies, crafting one cell into two. That replication event begins with a set of proteins--the Origin Recognition Complex (ORC). And, with some cancers and developmental diseases linked to ORC proteins, structural biologists need to see how the complex works so they can understand how it might go wrong.
University of Guelph researchers are the first to discover that adolescents react differently to e-cigarette vapour than adults.
Led by Prof. Jibran Khokhar, Department of Biomedical Science in U of G's Ontario Veterinary College, the rodent-based research measured behavioural responses related to vaping.
"This is the first study to show that rodents find e-cigarette vapour rewarding in a conditioned place preference experiment," Khokhar said,?referring to animals' preference for a chamber in which experimenters previously exposed them to a drug.