Brain

Some antibiotics appear to be effective against a form of skin cancer known as melanoma. Researchers at KU Leuven, Belgium, examined the effect of these antibiotics on patient-derived tumours in mice. Their findings were published in the Journal of Experimental Medicine.

Researchers from KU Leuven may have found a new weapon in the fight against melanoma: antibiotics that target the 'power plants' of cancer cells. These antibiotics exploit a vulnerability that arises in tumour cells when they try to survive cancer therapy.

COLUMBUS, Ohio - The parasites that cause severe malaria are well-known for the sinister ways they infect humans, but new research may lead to drugs that could block one of their most reliable weapons: interference with the immune response.

In the study, scientists defined the atomic-level architecture of the connection between a protein on the surface of a parasite-infected red blood cell when it binds to a receptor on the surface of an immune cell.

As the world warms, sweeping changes in marine nutrients seem like an expected consequence of increased ocean temperatures. However, the reality is more complicated. New research suggests that processes below the ocean surface may be controlling what is happening above.

WASHINGTON, July 20, 2021 -- In the wind power industry, optimization of yaw, the alignment of a wind turbine's angle relative to the horizonal plane, has long shown promise for mitigating wake effects that cause a downstream turbine to produce less power than its upstream partner. However, a critical missing puzzle piece in the application of this knowledge has recently been added -- how to automate the identification of which turbines are experiencing wake effects amid changing wind conditions.

Chinese researchers along with international colleagues recently reported a 6,700-year-long, precisely dated and well-calibrated tree-ring stable isotope chronology from the Northeastern Tibetan Plateau. It reveals full-frequency precipitation variability in the Asian Summer Monsoon (ASM) from interannual to multimillennial timescales with a long-term decreasing trend and several abrupt climate change events.

New Rochelle, NY, July 19, 2021--Duct tape and items retrieved from the water are common pieces of evidence in forensic cases. A new study evaluates the recovery of DNA from folded duct tape that has been submerged in ocean water for up to 2 weeks. The study is published in the peer-reviewed journal Forensic Genomics. Click here to read the article now.

Decreasing bacterial acidity could help reduce antimicrobial resistance by eliminating bacteria that can survive being treated with antibiotics.

Scientists at the University of Exeter have developed a novel method, which allows users to measure the pH of individual bacteria before, during and after treatment with antibiotics.

The research, published in the journal mBio, lays the foundation for understanding the special properties of bacteria that survive being treated with antibiotics, so that new ways of targeting them can be developed.

Researchers in the BOTTLE Consortium, including from the U.S. Department of Energy's (DOE's) National Renewable Energy Laboratory (NREL) and the University of Portsmouth, have identified using enzymes as a more sustainable approach for recycling polyethylene terephthalate (PET), a common plastic in single-use beverage bottles, clothing, and food packaging that are becoming increasingly relevant in addressing the environmental challenge of plastic pollution.

What The Study Did: The experiences, perspectives and needs of transgender young people in accessing health care are described in this review of 91 studies.

Authors: Lauren S. H. Chong, M.D., of the Children's Hospital at Westmead in Sydney, Australia, is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamapediatrics.2021.2061)

The MOMAT research group from Universidad Complutense de Madrid has worked with Universidad de Almería, to develop a mathematical model that simulates the impact of SARS-CoV-2 strains and vaccines together, combined with many other biological and social processes in the propagation of COVID-19.

The tool can be downloaded without restriction and free of charge and applied to any territory. It forms part of the family of θ-SIR models, which were initially developed by the MOMAT research group itself before the arrival of new variants and the development of vaccines.

Analysis of children and young people's proximity to woodlands has shown links with better cognitive development and a lower risk of emotional and behavioural problems, in research led by UCL and Imperial College London scientists that could influence planning decisions in urban areas.

Two common practices in the U.S. restaurant industry -- service with a smile and tipping -- contribute to a culture of sexual harassment, according to new research from the University of Notre Dame.

"A perfect storm: Customer sexual harassment as a joint function of financial dependence and emotional labor" was recently published in the Journal of Applied Psychology from Timothy Kundro, assistant professor of management and organization at Notre Dame's Mendoza College of Business.

An internal transporter that enables us to use the copper we consume in foods like shellfish and nuts to enable a host of vital body functions also has the essential role of protecting the receptor that enables us to grow new blood vessels when ours become diseased, Medical College of Georgia scientists report.

Living organisms are often exposed to stress stimuli generated either by external or internal factors, and they need to respond accordingly. At a cellular level, stress usually triggers the activation of survival pathways that contribute to the recovery of cell homeostasis. However, when stress is too high, a process of cell death is initiated that eliminates the damaged cell.

According to the World Health Organization, over 340 million children and adolescents (aged 5 to 10 years old) were classified as overweight or obese in 2016, a statistic that has risen from 14% since 1975. Childhood obesity is associated with a wide range of severe health complications and an increased risk of premature onset of illnesses, including diabetes and heart disease. Without intervention, children and young adolescents classified as obese are likely to remain so throughout adolescence and adulthood.