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A class of drugs used to treat certain breast cancers could help to tackle lung cancers that have become resistant to targeted therapies, suggests a new study in mice from the Francis Crick Institute and the Institute of Cancer Research (ICR).
The research, published in Cell Reports, found that lung tumours in mice caused by mutations in a gene called EGFR shrunk significantly when a protein called p110α was blocked.
Researchers applied a machine learning technique that could potentially translate patterns of activity in fear-processing brain regions into scores on questionnaires used to assess a patient's fear of pain. This neuroscientific approach, reported in eNeuro, may help reconcile self-reported emotions and their neural underpinnings.
On today's increasingly crowded globe, human migration can strain infrastructure and resources. Accurate data on migration flows could help governments plan for and respond to immigrants. Yet these figures, when available, tend to be spotty and error-ridden, even in the developed world. Researchers have developed approaches to estimate migration rates, but even the best of these rely on unrealistic assumptions about the mass movement of people and yield migration rates that can fall far below reality.
DURHAM, N.C. -- A new study from Duke University and Fudan University in China is the first to estimate how much Chinese residential electricity consumption would increase due to climate change. It's a lot.
By the end of the 21st century, each degree Celsius increase in global mean surface temperature (GMST) would raise average Chinese residential electricity use by about 9 percent.
Peak electricity use will rise 36 percent for every increased degree Celsius.
An international team of scientists including an employee of I.M. Sechenov First Moscow State Medical University (MSMU) developed a device for mixing chemical and biological reaction feeds. The team managed to increase the mixing efficiency up to 90%. The new device will be used in biological and chemical experiments. The article of the scientists was published in the RSC Advances journal.
Fragmentation of wildlife populations is increasing on a global scale, and understanding current genetic structure, genetic diversity and genetic connectivity is key to informing future wildlife management and conservation.
This is true of mountain lion -- also known as pumas or cougars -- populations in California, according to a new study conducted by a University of Wyoming research team.
Earlier this year, the United Nations announced some much-needed, positive news about the environment: The ozone layer, which shields the Earth from the sun's harmful ultraviolet radiation, and which was severely depleted by decades of human-derived, ozone-destroying chemicals, is on the road to recovery.
You might have seen Hollywood stars in "motion capture" suits, acting in full-body costumes peppered with sensors that let a computer transform them into a Hulk or a dragon or an enchanted beast.
Unlike other skin cancers - and without knowing really why - melanoma is one of the most aggressive tumours, with potential for metastasis from very early stages, when lesions are just millimetres thick. Most puzzling is that these metastases occur in an apparently chaotic way, as they involve many processes that occur simultaneously but do not appear to have an apparent relationship among them.
The steady production of sperm relies on the number of sperm stem cells in the testis remaining constant. Researchers including Asst. Prof. Yu Kitadate and Prof. Shosei Yoshida (developmental biologists at the National Institute for Basic Biology within the National Institutes of Natural Sciences in Japan) and Prof. Benjamin Simons (a theoretical physicist at the University of Cambridge in the UK) have revealed a novel mechanism for stem cell number control.
A faster, more cost-efficient, and more accurate method of examining the effectiveness of human pluripotent stem-cell-derived cardiac muscle cells has been discovered, according to researchers from Penn State.
Human pluripotent stem cells (hPSCs) -- human embryonic stem cells and induced pluripotent stem cells -- can be induced to produce other types of human cells through stem cell differentiation. The researchers looked at cardiac muscle cells -- cardiomyocytes (CMs) -- in this study.
Suppose you were building a cartel -- a group of business interests who coordinate to fix high prices that consumers must pay. How would you design it? Received economic wisdom says transparency among cartel members is crucial: If colluding suppliers share information, they can keep prices high and monitor members of the cartel to make sure no one deviates from the cartel's norms.
DETROIT - Declarative memory -- memories that can be consciously recalled -- is critical to everyday life. Throughout childhood and adolescence, declarative memory improves remarkably. However, until most recently, there was a critical gap in our understanding of how maturation of the prefrontal cortex drives memory development.
KINGSTON, R.I. - December 19, 2018 - Oceanographers at the University of Rhode Island have found that even slight levels of ocean oxygen loss, or deoxygenation, have big consequences for tiny marine organisms called zooplankton.
Known for exceptional mimicry, stick insects have evolved a range of egg-laying techniques to maximize egg survival while maintaining their disguise – including dropping eggs to the ground, skewering them on leaves, and even enlisting ants for egg dispersal. Scientists have now combined knowledge on these varied techniques with DNA analysis to create the best map of stick-insect evolution to date. Contrary to previous evolutionary theories based on anatomical similarities, the new analysis finds the first stick insects flicked or dropped their eggs while hiding in the foliage.