Culture
PHILADELPHIA -- A recent study published in the journal Nature Medicine, led by researchers James Riley, PhD, a professor of Microbiology at the Perelman School of Medicine at the University of Pennsylvania, and Todd Allen, PhD, a professor of Medicine at Harvard Medical School and Group Leader at the Ragon Institute of MGH, MIT and Harvard, describes a new Dual CAR T cell immunotherapy that can help fight HIV infection. The paper's first authors are Colby Maldini, a graduate student at the University of Pennsylvania and Daniel Claiborne, PhD, a research fellow at the Ragon Institute.
Particle accelerators generate high-energy beams of electrons, protons and ions for a wide range of applications, including particle colliders that shed light on nature's subatomic components, X-ray lasers that film atoms and molecules during chemical reactions and medical devices for treating cancer.
Metformin is the first-line treatment for most cases of type 2 diabetes and one of the most commonly prescribed medications worldwide, with millions of individuals using it to optimise their blood glucose levels.
A new research study, conducted over six years in the Sydney Memory and Ageing Study in 1037 Australians (aged 70 to 90 years old at baseline), has revealed an additional effect: individuals with type 2 diabetes who used metformin experienced slower cognitive decline with lower dementia rates than those who did not use the medication.
Computational biologists at the University of Toronto have developed an artificial intelligence algorithm that has the potential to create novel protein molecules as finely tuned therapeutics.
Misconceptions about child marriage (marriage under 18) appear widespread among the American public, potentially hampering efforts to address the practice globally. David Lawson and colleagues at the University of California, Santa Barbara, present these findings in the open-access journal PLOS ONE on September 23, 2020.
Antibiotic resistance is one of the world's most urgent public health threats. In the United States alone, tens of thousands of deaths result each year from drug-resistant strains of common bacteria such as Staphylococcus aureus and Enterococcus faecium, which can cause virtually untreatable hospital-acquired infections. Perilously few new classes of antibiotics are being developed to fight infections that have become resistant to traditional treatments, and bringing any new drugs to market could take decades.
What The Study Did: The potential use of red blood cell distribution width for risk stratification of patients with COVID-19 was looked at in this observational study.
Authors: John M. Higgins, M.D., and Jonathan C. T. Carlson, M.D., Ph.D., of Massachusetts General Hospital and Harvard Medical School in Boston, are the corresponding authors.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamanetworkopen.2020.22058)
The warmer it gets, the faster Antarctica loses ice - and much of it will then be gone forever. Consequences for the world's coastal cities and cultural heritage sites would be detrimental, from London to Mumbai, and from New York to Shanghai. That's what a team of researchers from the Potsdam Institute for Climate Impact Research, Potsdam University and New York's Columbia University has found out in their new study, published in Nature (cover story), on how much warming the Antarctic Ice Sheet can survive.
What The Study Did: Researchers investigated whether cannabis use during pregnancy was associated with various childhood outcomes, including cognition, social problems and brain structure.
Authors: Sarah E. Paul, B.A., and Ryan Bogdan, Ph.D., of Washington University in St. Louis, are the corresponding authors.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamapsychiatry.2020.2902)
The cells that make up our body are tiny, each of them measuring only micrometers in diameter. The ensemble of chromosomal DNA molecules that encode the genome, on the other hand, measures almost 2 meters. In order to fit into cells, chromosomal DNA is folded many times. But the DNA is not merely squeezed into the nucleus in a random manor but folded in a specific and highly regulated structure.
TAMPA, Fla. (Sept. 23, 2020)- More than 200,000 people in the U.S. have died from COVID-19. Some argue that statistic is inaccurate due to inconsistencies in how deaths are being reported. But researchers from the University of South Florida claim that even if those deaths have been correctly measured, the number doesn't fully convey the true mortality effects of COVID-19.
Scientists have developed a tool for studying the biting behaviour of common pathogen-carrying mosquitoes, according to new research published this week in eLife.
The tool, which uses an artificial blood meal and a surface that mimics human skin, will provide detailed understanding of blood feeding without using human subjects as bait. It can also fit conveniently into a backpack, allowing the study of mosquitoes in laboratory and natural environments.
Tsukuba, Japan - Normal brain development requires a precise interplay between neuronal and non-neuronal (also called glial) cells. In a new study, researchers from the University of Tsukuba revealed how the loss of protein arginine methyltransferase (PRMT) 1 causes disruptions in glial cells and affects proper brain development.
College students are under a lot of stress, even more so lately due to the COVID-19 pandemic. Based on certain personality types, especially neurotic personalities, college health courses could help students develop a more positive stress mindset, according to research from faculty at Binghamton University, State University of New York.
September 23, 2020 - More than two-thirds of women orthopaedic surgeons report experiencing sexual harassment during their residency training, according to a survey study in Clinical Orthopaedics and Related Research® (CORR®), a publication of The Association of Bone and Joint Surgeons