Culture

New research presented at this year's annual meeting of the European Association for the Study of Diabetes (EASD), held online this year, shows the importance of good cardiovascular health in preventing type 2 diabetes (T2D) among middle-aged individuals, regardless of any genetic predisposition they may have towards developing the disease. The study was conducted by Kan Wang, Dr. Fariba Ahmadizar, and colleagues at the Department of Epidemiology, Erasmus University Medical Centre, Rotterdam, the Netherlands.

The following papers will be presented at a Lancet journals' session at ECCVID 2020, organised by European Society of Clinical Microbiology and Infectious Diseases. The conference will take place online on Wednesday 23rd to Friday 25th September 2020, the society's first online conference focussing exclusively on COVID-19.

Contact details for corresponding authors are provided should you wish to arrange an interview the authors. Funding information is listed on the first page of each Article.

Timely preventive measures against COVID-19 such as providing hotel room accommodation for homeless people in the UK are estimated to have prevented hundreds of deaths in this vulnerable population, according to research presented at this week's ESCMID Conference on Coronavirus Disease (ECCVID, held online 23-25 September) and published in The Lancet Respiratory Medicine ahead of a special conference session featuring The Lancet journals.

DALLAS (September 23, 2020) - Researchers at Center for BrainHealth®, part of The University of Texas at Dallas, recently examined how cells in the brains of people at risk for developing Alzheimer's disease make and use energy. Relationships between the brain's energy metabolism and the risk of Alzheimer's disease have been reported previously.

Two nationwide COVID-19 antibody seroprevalence studies from Brazil show that many cities along the Amazon were hit hardest at the beginning of the epidemic in May and June, along with poorer and Indigenous communities. The research is presented at this week's ESCMID Conference on Coronavirus Disease (ECCVID, held online 23-25 September) and published in The Lancet Global Health, as part of a special conference session featuring The Lancet journals.

New Rochelle, NY, September 23, 2020 - Forensic DNA analysis enables new and increasingly sophisticated technology for solving cold cases. Through advances in DNA sequencing and bioinformatics, this relatively new and urgent field is enabling a broad range of cold cases, including homicides and other violent crimes, to be solved. The first issue of Forensic Genomics has just been published.

New research presented at this week's ESCMID Conference on Coronavirus Disease (ECCVID, online 23-25 September) confirms that men with COVID-19 have worse outcomes than women, possibly related to them experiencing higher levels of inflammation. The study is by Dr Frank Hanses, University Hospital Regensburg, Germany, and colleagues, and shows that men have a 62% increased risk of COVID-19 associated death compared with women, after adjustment for various factors. (see figure 2 of poster).

A US study from the city of Detroit, presented at this week's ESCMID Conference on Coronavirus Disease (ECCMID, online 23-25 September) shows that the initial SARS-CoV-2 viral load in nasopharyngeal samples has been decreasing as the pandemic progressed. The authors also observed that the decline in viral load was associated with a decrease in death rate. The study is by Dr Said El Zein, Wayne State University/ Detroit Medical Center, Detroit, MI, USA, and colleagues.

New research presented at this week's ESCMID Conference on Coronavirus Disease (ECCVID, online 23-25 September) suggests that, as lockdown took effect and case numbers dropped, the amount of virus patients were exposed to (viral load) fell, and this could be linked to lower proportions of patients requiring intensive care and dying. The study is by Dr Chiara Piubelli, IRCCS Sacro Cuore Don Calabria Hospital, Negrar, Italy, and colleagues.

There are no Food and Drug Administration (FDA)-approved treatments for COVID-19, the pandemic infection caused by a novel coronavirus. While several therapies are being tested in clinical trials, current standard of care involves providing patients with fluids and fever-reducing medications. To speed the search for new COVID-19 therapies, researchers are testing repurposed drugs -- medicines already known to be safe for human use because they are FDA-approved for other conditions -- for their abilities to mitigate the virus.

AMHERST, Mass. - In a new climate modeling study that looked at the impacts of accelerated ice melt from the Antarctic Ice Sheet (AIS) on future climate, a team of climate scientists reports that future ice-sheet melt is expected to have significant effects on global climate.

First author and graduate student Shaina Sadai at the University of Massachusetts Amherst, with Alan Condron of the Woods Hole Oceanographic Institution, Rob DeConto at UMass Amherst and David Pollard at Pennsylvania State University, present details this week in Science Advances.

During pregnancy in mice, the billions of bacteria and other microbes that live in a mother's intestines regulate key metabolites, small molecules that are important for healthy fetal brain development, UCLA biologists report Sept. 23 in the journal Nature.

A neighborhood's overall socioeconomic status, including income and education level, may influence its residents' risk of chronic kidney disease, according to a study recently published in SSM Population Health by researchers from Drexel University's Dornsife School of Public Health.

Researchers at the University of Alberta have discovered a novel, second mechanism of action by the antiviral drug remdesivir against SARS-CoV-2, according to findings published today in the Journal of Biological Chemistry.

University of Houston researchers have found that during early pregnancy, the mix of alcohol and nicotine significantly alters the gene regulatory pathways of the developing fetus, which can lead to major deficiencies in brain development. Metin Akay, founding chair and John S. Dunn Endowed Chair Professor of biomedical engineering is reporting the findings, the first study of its kind, in the Nature journal Scientific Reports.