Body
Mobility tracking using cell phone data showing greater movement of people is a strong predictor of increased rates of COVID-19, according to new data in CMAJ (Canadian Medical Association Journal).
Cancer therapy in recent times relies on the use of several drugs derived from biological sources including different bacteria and viruses, among others. However, these bio-based drugs get easily degraded and therefore inactivated on administration into the body. Thus, effective delivery to and release of these drugs at target tumor sites are of paramount importance from the perspective of cancer therapy.
New medicines for people who have diabetes seem to pop up all the time. Drugs that help the body break down carbohydrates, drugs that increase excretion of glucose in the urine, drugs that help muscles respond to insulin and drugs that stimulate the pancreas to produce it -- the list of pharmaceutical options to treat diabetes gets longer and longer.
HERSHEY, Pa.-- Social distancing and lockdowns may have reduced the spread of COVID-19, but researchers from Penn State College of Medicine also report those actions may have affected clinical researchers' ability to finish trials. Study completion rates dropped worldwide between 13% and 23%, depending on the type of research sponsor and geographic location, between April and October 2020.
INDIANAPOLIS--Worldwide, 1 in 4 people will suffer from a depressive episode in their lifetime.
While current diagnosis and treatment approaches are largely trial and error, a breakthrough study by Indiana University School of Medicine researchers sheds new light on the biological basis of mood disorders, and offers a promising blood test aimed at a precision medicine approach to treatment.
New research published in the British Journal of Pharmacology indicates that two currently available medications--an antifungal drug and an antidepressant--can effectively inhibit the virus that causes COVID-19 in laboratory cells.
Smoking increases symptoms and health risks for patients with rheumatic diseases, but interventions to help patients quit are rarely available at rheumatology clinics.
On the first day of the UK campaign for COVID-19 vaccination, there were reports of two cases of anaphylaxis—a severe, potentially life-threatening allergic reaction—within minutes of administration of the Pfizer/BioNTech mRNA vaccine. Subsequently further cases of suspected anaphylaxis to the Pfizer vaccine were reported. A new report published in Clinical & Experimental Allergy reveals that an allergy to the ingredient polyethylene glycol (PEG) is a cause of anaphylaxis to the vaccine. However, this is in the context of millions of doses safely administered.
April 6, 2021, Alexandria, VA - The American Academy of Otolaryngology?Head and Neck Surgery Foundation published the Clinical Practice Guideline: Opioid Prescribing for Analgesia After Common Otolaryngology Operations today in Otolaryngology-Head and Neck Surgery. This specialty-specific guideline provides evidence-based recommendations on postoperative management for pain in common otolaryngologic procedures, with a focus on opioids.
Misinformation about COVID-19 is spreading from the United States into Canada, undermining efforts to mitigate the pandemic. A study led by McGill University shows that Canadians who use social media are more likely to consume this misinformation, embrace false beliefs about COVID-19, and subsequently spread them.
CHAMPAIGN, Ill. -- Exposure to phthalates, a class of chemicals widely used in packaging and consumer products, is known to interfere with normal hormone function and development in human and animal studies. Now researchers have found evidence linking pregnant women's exposure to phthalates to altered cognitive outcomes in their infants.
Most of the findings involved slower information processing among infants with higher phthalate exposure levels, with males more likely to be affected depending on the chemical involved and the order of information presented to the infants.
Bethesda, MD (April 6, 2021) -- Obesity is a global pandemic, affecting about 40% of adults in the United States. There is an enormous unmet need for an effective weight-loss solution. After a detailed review of available literature, the American Gastroenterological Association (AGA) has released new clinical guidelines recommending the use of intragastric balloons (IGB) for patients with obesity who have not been able to lose weight with traditional weight-loss strategies.
Researchers have uncovered pathways involved in the body's response to glucocorticoid treatments and identified a novel biomarker that could be used to monitor how these drugs work in patients, according to a clinical study published today in eLife.
A more reliable indicator of an individual's response to glucocorticoid drugs could be used to develop a clinically applicable test that could help tailor treatments and potentially minimise side-effects.
Nursing mothers who receive a COVID-19 vaccine may pass protective antibodies to their babies through breast milk for at least 80 days following vaccination, suggests new research from Washington University School of Medicine in St. Louis.
Below please find a summary and link to new coronavirus-related content published today in Annals of Internal Medicine. All coronavirus-related content published in Annals of Internal Medicine is free to the public. A complete collection is available at https://annals.org/aim/pages/coronavirus-content.
Graded dosing protocol may help patients with first dose reactions tolerate second dose of vaccine