Body

WHO Ingrid Katz, MD, MHS, Associate Physician, Department of Medicine, Brigham and Women's Hospital; lead author of a new Perspective piece published in the New England Journal of Medicine.

In 2020, the International Agency for Research on Cancer of the World Health Organization stated that breast cancer accounts for most cancer morbidities and mortalities in women worldwide. This alarming statistic not only necessitates newer methods for the early diagnosis of breast cancer, but also brings to light the importance of risk prediction of the occurrence and development of this disease.

Up to one in five employees at an academic medical institution are considering leaving their professions due to the strains of coping with the pandemic in their own lives, according to a new University of Utah Health study. Individuals who had caregiving responsibilities were among those most likely to contemplate leaving or reducing hours.

The findings suggest that retaining highly trained doctors, nurses, and scientists in the aftermath of the COVID-19 pandemic could be the next great health care challenge.

What The Study Did: Researchers compared rates of health maintenance organization (HMO) enrollment, by race and ethnicity, for children with commercial and public coverage with the use of national survey data.

Authors: Alon Peltz, M.D., M.B.A., M.H.S., of Harvard Medical School in Boston, is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamanetworkopen.2021.4162)

More than 60% of U.S. adults who vape are interested in quitting, according to a study published today in JAMA Network Open by MUSC Hollings Cancer Center researchers. And among those who vape to help them to quit smoking, some are successful while others continue smoking and using electronic cigarettes.

The study, which analyzed longitudinal survey data from more than 30,000 adults across the country, aimed to provide the most up-to-date estimate of how many Americans are interested in stopping their use of e-cigarettes or have made past attempts to quit.

A personalized tumor cell vaccine strategy targeting Myc oncogenes combined with checkpoint therapy creates an effective immune response that bypasses antigen selection and immune privilege, according to a pre-clinical study for neuroblastoma and melanoma. The neuroblastoma model showed a 75% cure with long-term survival, researchers at Children's National Hospital found.

WEST LAFAYETTE, Ind. -- If you walk with your spouse or partner on a regular basis, you might want to speed up. Or tell them to.

A new study by Purdue University nursing, health and kinesiology, and human development and family studies researchers shows that couples often decreased their speed when walking together. Speed further decreased if they were holding hands.

New research led by investigators from Boston Medical Center and Grady Memorial Hospital demonstrates the significant decline in hospitalizations for neurological emergencies during the COVID-19 pandemic. The rate of Subarachnoid hemorrhage (SAH) - bleeding in the space between the brain and the tissue covering the brain - hospitalizations declined 22.5 percent during the study period, which is consistent with the other reported decreases in emergencies such as stroke or heart attacks.

PHILADELPHIA - A Penn Medicine patient with a genetic form of childhood blindness gained vision, which lasted more than a year, after receiving a single injection of an experimental RNA therapy into the eye. The clinical trial was conducted by researchers at the Scheie Eye Institute in the Perelman School of Medicine at the University of Pennsylvania. Results of the case, detailed in a paper published today in Nature Medicine, show that the treatment led to marked changes at the fovea, the most important locus of human central vision.

A possible explanation for why many cancer drugs that kill tumor cells in mouse models won't work in human trials has been found by researchers with The University of Texas Health Science Center at Houston (UTHealth) School of Biomedical Informatics and McGovern Medical School.

The research was published today in Nature Communications.

Exposure to antibiotics in utero and infancy can lead to an irreversible loss of regulatory T-cells in the colon-a valuable component of the immune system's response toward allergens in later life - after only six months, a Rutgers researcher found.

The study was published in the journal mBio.

Video games offer students obvious respite from the stresses of studies and, now, a study from a University of Ottawa medical student has found they could benefit surgical skills training.

As the COVID-19 pandemic lingers, researchers have found associations between certain lifestyle factors and a person's risk of getting infected. While it has already been established that those with Type II diabetes and a high body mass index (BMI) are at greater risk of experiencing hospitalizations and other severe complications related to COVID-19, they are also at greater risk of getting symptomatic infection in the first place.

Washington, DC, April 1, 2021 - A study in the Journal of the American Academy of Child and Adolescent Psychiatry (JAACAP), published by Elsevier, reports that middle schoolers from a predominantly Latinx community, with elevated levels of mental health problems, showed a reduction in symptoms during the early stages of the pandemic.

LOS ANGELES (April 1, 2021) -- A single dose of the Pfizer-BioNTech vaccine for individuals who previously had COVID-19 generates an immunologic response similar to that of individuals receiving the two-dose recommended sequence, according to a Cedars-Sinai study published today by the journal Nature Medicine.