Body

Experts have uncovered a new molecular reason why faecal transplants are highly effective in treating infections such as C. difficile (a nasty bacteria that can infect the bowel), which could lead to more targeted treatments for this and other similar diseases.

The study, published today in Gastroenterology, was led by experts from the University of Nottingham and Nottingham Trent University.

What The Study Did: This survey study examines wh0 U.S. adults believe should be prioritized for access to COVID-19 vaccines.

Authors: Ezekiel J. Emanuel, M.D., Ph.D., of the University of Pennsylvania Perelman School of Medicine in Philadelphia, is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamanetworkopen.2021.7943)

Nine out of ten Danes say that they will accept the COVID-19 vaccine when offered. This is the same level as before the AstraZeneca vaccine was paused.

This is shown by a questionnaire-based survey collected by Søren Dinesen Østergaard and co-authors. He is professor at the Department of Clinical Medicine at Aarhus University and affiliated with the Department of Affective Disorders at Aarhus University Hospital, Psychiatry.

An international team of scientists led by microbiologists Professor Alexander Loy from the University of Vienna and Professor David Schleheck from the University of Konstanz has uncovered new metabolic capabilities of gut bacteria. For the first time, the researchers have analyzed how microbes in the gut process the plant-based, sulfur-containing sugar sulfoquinovose. Sulfoquinovose is a sulfonic acid derivative of glucose and is found in all green vegetables such as spinach and lettuce.

Diet and the gut microbiome

Washington, DC (April 9, 2021) -- The American Society of Nephrology (ASN) and the National Kidney Foundation (NKF) announce the concurrent publication of "Special Article: Reassessing the Inclusion of Race in Diagnosing Kidney Diseases: An Interim Report from the NKF-ASN Task Force" in the Journal of the American Society of Nephrology (JASN) and the American Journal of Kidney Diseases (AJKD).

When setting SARS-CoV-2 vaccine priorities, Canada should take a more nuanced approach that considers geographic and occupational risk exposures, as 75% of Canadian adults have at least 1 risk factor for severe COVID-19, argues an analysis in CMAJ (Canadian Medical Association Journal).

BOSTON -- Videos of people experiencing severe neurological symptoms, including convulsions and difficulty walking, purportedly after receiving a COVID-19 vaccine, have surfaced on Facebook, YouTube and other social media channels. The millions of people watching these videos might conclude that the vaccine is either quite dangerous to produce such symptoms or that the people in the videos are faking their symptoms.

It's time for a more nuanced approach to prioritizing COVID-19 vaccinations as more contagious variants become prevalent and a third wave of infections threatens to overwhelm hospitals in some provinces, according to an analysis published today in the Canadian Medical Association Journal.

Editor's note: This release is adapted from a press release issued by the American Thoracic Society.

LOS ANGELES -- Early results from a new, pioneering chimeric antigen receptor (CAR) T cell immunotherapy trial led by researchers at the UCLA Jonsson Comprehensive Cancer Center found using a bilateral attack instead of the conventional single-target approach helps minimizes treatment resistance, resulting in long-lasting remission for people with non-Hodgkin's B-cell lymphoma that has come back or has not responded to treatment.

WASHINGTON, April 9, 2021 -- For the millions of people worldwide who have sickle cell disease, there are only a few treatment options, which include risky bone marrow transplants, gene therapy or other treatments that address a subset of symptoms. Today, researchers will describe the discovery of a small molecule with the potential to address the root cause of sickle cell disease by boosting levels of fetal hemoglobin, a healthy form that adults normally do not make. The drug could be formulated into a convenient daily tablet.

Obesity is linked to heavier periods and may be caused by delayed repair of the womb lining, according to a study published in the Journal of Endocrinology. Using a combined approach, assessing both women and mice, the study suggests an association between higher body weight and greater menstrual blood loss that may result from increased inflammation in the womb lining, delaying its repair.

Early results show that a new combination drug therapy is safe and effective against advanced skin cancer in patients who were not able to have their tumors surgically removed.

The drug combination is among the first, researchers say, to demonstrate the potential value of a live common cold virus, a coxsackievirus, to infect and kill cancer cells.

As demonstrated by multiple studies over the years, women who breastfeed have a lower risk for developing cardiovascular disease and diabetes when compared to those who don't or can't. However, the mechanisms by which these risks are reduced for lactating women are still not fully understood.