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COLUMBUS, Ohio ¬- New data published by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James) suggests that an oral drug currently used in the clinical setting to treat neuromuscular diseases could also help prevent a common form of skin cancer caused by damage from ultraviolet-B (UVB) radiation from the sun.

Studies show wearing masks and social distancing can contain the spread of the COVID-19 virus, but their combined effectiveness is not precisely known.

In Chaos, by AIP Publishing, researchers at New York University Tandon School of Engineering and Politecnico di Torino in Italy developed a network model to study the effects of these two measures on the spread of airborne diseases like COVID-19. The model shows viral outbreaks can be prevented if at least 60% of a population complies with both measures.

PLYMOUTH MEETING, PA [April 13, 2021] -- The April 2021 issue of JNCCN--Journal of the National Comprehensive Cancer Network publishes new research from Memorial Sloan Kettering Cancer Center (MSK) and Gustave Roussy Institute, which suggests that baseline brain imaging should be considered in most patients with metastatic kidney cancer.

Biomedical scientists are increasingly using deconvolution methods, those used to computationally analyze the composition of complex mixtures of cells. One of their challenges is to select one method that is appropriate for their experimental conditions among nearly 50 available.

A gene therapy protects eye cells in mice with a rare disorder that causes vision loss, especially when used in combination with other gene therapies, shows a study published today in eLife.

The findings suggest that this therapy, whether used alone or in combination with other gene therapies that boost eye health, may offer a new approach to preserving vision in people with retinitis pigmentosa or other conditions that cause vision loss.

Violent blows or jolts to the head can cause traumatic brain injury (TBI), and there are currently about five million people in the U.S. living with some form of chronic impairment after suffering a TBI. Even in a mild form, TBI can lead to lifelong nerve cell deterioration associated with a wide array of neuropsychiatric conditions. Tragically, there are no medicines to protect nerve cells after injury. Behind aging and genetics, TBI is the third leading cause of Alzheimer's disease (AD), yet the link between these two conditions is not understood.

AMES, Iowa - Narratives are a powerful tool that can help explain complex issues, but they can also serve as sources of misinformation, which presents a challenge as public health agencies work to educate people about COVID-19 vaccine.

PITTSBURGH, April 13, 2021 - What can vaccine proponents, clinicians and public health communicators learn from "anti-vaxxers?" A lot, according to new guidance for pro-vaccination social media events written by University of Pittsburgh health scientists.

What The Study Did: The results of incorporating HIV screening into COVID-19 testing at an emergency department in Chicago are reported in this study.

Authors: David Pitrak, M.D., of the University of Chicago Medicine, is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamainternmed.2021.0839)

What The Study Did: This modeling study estimates COVID-19-related changes in rates of colorectal cancer screenings and associated outcomes and estimates the degree to which expanded fecal immunochemical testing could potentially mitigate these outcomes.

Authors: Rachel B. Issaka, M.D., M.A.S., of the Fred Hutchinson Cancer Research Center in Seattle, is the corresponding author.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

New research from CU Cancer Center member Scott Cramer, PhD, and his colleagues could help in the treatment of men with certain aggressive types of prostate cancer.

Published this week in the journal Molecular Cancer Research, Cramer's study specifically looks at how the loss of two specific prostate tumor-suppressing genes -- MAP3K7 and CHD1 --increases androgen receptor signaling and makes the patient more resistant to the anti-androgen therapy that is typically administered to reduce testosterone levels in prostate cancer patients.

Using laboratory-grown roundworms as well as human and mouse eye tissue, University of Maryland School of Medicine (UMSOM) researchers have identified a new potential mechanism for age-related macular degeneration--the leading cause of blindness among older adults. The UMSOM researchers say that the findings suggest a new and distinct cause that is different from the previous model of a problematic immune system, showing that the structural organization of the eye's light-detecting cells may be affected by the disease.

Tsukuba, Japan - Non-alcoholic fatty liver disease (NAFLD) is the most common liver disorder worldwide, affecting as much as a quarter of humanity. It is characterized by fat accumulation in liver cells and may progress to inflammation, cirrhosis and liver failure. Now, researchers at the University of Tsukuba reveal the positive effects, beyond the expected weight-loss benefit, of exercise on the liver.

Tsukuba, Japan--Liver disease, from metabolic and bacterial causes, is a growing concern. What connects these dots? The gut, or more specifically, bacteria in the gut. Bacteria that cause inflammation in the mouth are transported through the digestive tract to the gut and liver, where they can cause liver inflammation. Lipopolysaccharides, important structural molecules in some bacteria, act as endotoxins, producing systemic effects that can manifest as non-alcoholic fatty liver disease (NAFLD).

New Orleans, LA - A study led by Hui-Yi Lin, Ph.D., Professor of Biostatistics, and a team of researchers at LSU Health New Orleans Schools of Public Health and Medicine has found that adequate levels of five antioxidants may reduce infection with the strains of the human papillomavirus (HPV) associated with cervical cancer development. Findings are published in the Journal of Infectious Diseases.