Scientists at The University of Nottingham have been awarded over £366,000 to help unravel the mystery of a stomach bug which causes gastric ulcers and cancer. Their research could lead to the development of a vaccine for those most at risk.
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Studies of the enzyme CTP synthetase in the parasite Trypanosoma brucei have brought researchers at Umeå University in Sweden closer to a cure for African sleeping sickness. Their findings are now being published in the April issue of The Journal of Biological Chemistry.
Nanotechnology is the ability to measure, see, manipulate and manufacture things usually between 1 and 100 nanometers. A nanometer is one billionth of a meter; a human hair is roughly 100,000 nanometers wide. More than $30 billion in products incorporating nanotechnology were sold globally in 2005. By 2014, Lux Research estimates this figure will grow to $2.6 trillion.
Despite the potential for conflict of interest, virtually all practicing physicians in the U.S. have some form of relationship with pharmaceutical manufacturers but the nature and extent of those relationships vary, depending on the kind of practice, medical specialty, patient mix, and professional activities, reports a study in the April 26 issue of the New England Journal of Medicine.
A Johns Hopkins team has stopped in its tracks a form of blood cancer in mice by engineering and inactivating an enzyme, telomerase, thereby shortening the ends of chromosomes, called telomeres.
"Normally, when telomeres get critically short, the cell commits suicide as a means of protecting the body," says Carol Greider, Ph.D., the Daniel Nathans chair of molecular biology and genetics at Johns Hopkins. Her study, appearing online this month at Cancer Cell, uncovers an alternate response where cells simply - and permanently - stop growing, a process known as senescence.
University of Virginia researchers have discovered that microRNAs, a form of genetic material, can function as tumor suppressors in laboratory studies.
In the May 1 issue of Genes & Development, UVa researchers Drs. Yong Sun Lee and Anindya Dutta have shown that microRNAs can suppress the overexpression of a gene called HMGA2. This gene is related to creation of fatty tissue and certain tumors, as well as diet-induced obesity.
MicroRNA is a single-stranded RNA that is typically only 20-25 nucleotides long and is related to regulating the expression of other genes.
Consumers may claim they don't like diet soda because of the taste of artificial sweeteners, but Shelly Schmidt, a University of Illinois professor of food chemistry, thinks people are also influenced by a subtle difference called "mouth-feel." Think body, fullness, thickness; regular soda contains high-fructose corn syrup, diet soda doesn't.
One out of three sexually active older adults infected with HIV has unprotected sex, according to a study by Ohio University researchers. A survey of 260 HIV-positive older adults found that of those having sex, most were male, took Viagra and were in a relationship.
The total number of carbon atoms on Earth is fixed – they are exchanged between the ocean, atmosphere, land and biosphere. The fact that human activities are pumping extra carbon dioxide into the atmosphere, by fossil fuel burning and deforestation, is well known.
A new hereditary breast cancer gene has been discovered by scientists at the Lundberg Laboratory for Cancer Research and the Plastic Surgery Clinic at the Sahlgrenska Academy in Sweden. The researchers found that women with a certain hereditary deformity syndrome run a nearly twenty times higher risk of contracting breast cancer than expected.
Several research teams around the world have long been searching for new hereditary breast cancer genes, but thus far few have been found.
Cell membranes are like two-dimensional fluids whose molecules are distributed evenly through lateral diffusion but many important cellular processes depend on cortical polarity, the locally elevated concentration of specific membrane proteins.
n experiment called "shining light through walls" would seem hard to improve upon.
But University of Florida physicists have proposed a way to do just that, a step they say considerably improves the chance of detecting one of the universe's most elusive particles, a candidate for the common but mysterious dark matter.
By utilizing ideas developed in disparate fields, from earthquake dynamics to random-field magnets, researchers at the University of Illinois have constructed a model that describes the avalanche-like, phase-slip cascades in the superflow of helium.
Just as superconductors have no electrical resistance, superfluids have no viscosity, and can flow freely. Like superconductors, which can be used to measure extremely tiny magnetic fields, superfluids could create a new class of ultra-sensitive rotation sensors for use in precision guidance systems and other applications.
The periodic table of elements, all 111 of them, just got a little competition. A new discovery by a University of Missouri-Columbia research team, published in Angewandte Chemie, the journal of the German Society of Chemists, allows scientists to manipulate a molecule discovered 50 years ago in such as way as to give the molecule metal-like properties, creating a new, "pseudo" element. The pseudo-metal properties can be adjusted for a wide range of uses and might change the way scientists think about attacking disease or even building electronics.
It doesn't take a rocket scientist to make a lot of money, according to new research.
A nationwide study found that people of below average intelligence were, overall, just about as wealthy as those in similar circumstances but with higher scores on an IQ test.
Furthermore, a number of extremely intelligent people stated they had gotten themselves into financial difficulty.
"People don't become rich just because they are smart," said Jay Zagorsky, author of the study and a research scientist at Ohio State University 's Center for Human Resource Research.