Body

A new study shows that aspirin therapy for coronary artery disease is four times more likely to be ineffective in women compared to men with the same medical history.

Historically, studies have shown that aspirin therapy is less effective in women than in men, but it has remained unclear how much less effective and whether this affects patient outcomes, said Michael Dorsch, clinical pharmacist and adjunct clinical instructor at the University of Michigan College of Pharmacy.

For the first time, scientists have used a laboratory mouse model to mimic the development of human alcohol-induced breast cancer.

Alcohol (EtOH) consumption -- even moderate -- is a well-established risk factor for breast cancer in women. A recent study showed that 60 percent of female breast cancers worldwide were attributable to alcohol consumption. Nevertheless, the mechanisms of alcohol-induced breast cancer are poorly understood.

In 1928, Alexander Fleming opened the door to treating bacterial infections when he stumbled upon the first known antibiotic in a Penicillium mold growing in a discarded experiment.

The mouth is a tough environment, which is why dentists do not give lifetime guarantees. Despite their best efforts, a filling may eventually crack under the stress of biting, chewing and teeth grinding, or secondary decay may develop where the filling binds to the tooth. Fully 70 percent of all dental procedures involve replacements to existing repairs, at a cost of $5 billion per year in the United States alone.

This study examined whether a traditional low-impact mind–body exercise, Tai Chi, affects health-related quality-of-life (HRQOL) and headache impact in an adult population suffering from tension-type headaches.

According to the National Headache Foundation, more than 45 million Americans suffer from chronic headaches, with losses of $50 billion a year to absenteeism and medical expenses and an excess of $4 billion spent on over-the-counter medications.

The next 11-year cycle of solar storms will most likely start next March and peak in late 2011 or mid-2012—up to a year later than expected—according to a forecast issued by the NOAA Space Environment Center in coordination with an international panel of solar experts. The NOAA Space Environment Center led the prediction panel and issued the forecast at its annual Space Weather Workshop in Boulder, Colo. NASA sponsored the panel.

Depression may be an early symptom of Parkinson's disease, according to research that will be presented at the American Academy of Neurology's 59th Annual Meeting in Boston, April 28 – May 5, 2007.

Vitamin C is possibly the most important small molecule whose biosynthetic pathway remained a mystery. That is until now.

A group of Dartmouth and UCLA researchers, who normally work on genes involved in aging and cancer in animals, discovered the last piece of the puzzle, they report in a study published in the Journal of Biological Chemistry.

Arthritis cases on the rise, finds comparative national study, underscoring the need for cost-effective care and disability-reduction efforts

Ten genetic variants associated with type 2 diabetes, a disease which impacts more than 170 million people worldwide, have been identified or confirmed by a U.S.-Finnish team led by scientists at the University of Michigan School of Public Health.

The discoveries could lead to the development of new drugs for diabetes, permit more effective targeting of drug and behavioral therapies, and help scientists and physicians better predict who will develop diabetes, said Michael Boehnke, the Richard G. Cornell Collegiate Professor of Biostatistics at the U-M School of Public Health.

A generation of children born with HIV are now coming of age and reaching sexual maturity. Girls in this group who are sexually active are experiencing a higher number than expected of cervical abnormalities, a new study finds.

Researchers monitored the rate of first-time pregnancies, genital health and Pap test results of 638 girls, ages13 and over, who became infected with HIV around the time of birth. Nearly 50 percent of the girls had abnormal cervical cells.

An international has developed a prototype of the first fully integrated prosthetic arm that can be controlled naturally and provide sensory feedback, and allows for eight degrees of Freedom -- a level of control far beyond the current state of the art for prosthetic limbs.Jesse Sullivan, a former high-power lineman, lost both arms in 2001 after being shocked on the job. Here, he demonstrates the capabilities of the Proto 1 prosthetic arm system during clinical tests at the Rehabilitation Institute of Chicago.

Armed with more than a decade’s worth of statistics, researchers are sounding a new alarm about growing rates of syphilis among gay and bisexual men.

The overall number of syphilis cases in the United States fell from 50,578 in 1990 to just 7,177 in 2003 perhaps because of a nationwide prevention campaign aimed at heterosexuals. Nevertheless, gay men have seen their rates rise significantly in this decade.

Over time, more women are developing multiple sclerosis (MS) than men, according to research that will be presented at the American Academy of Neurology’s 59th Annual Meeting in Boston, April 28 – May 5, 2007.

In 1940, the ratio of women to men with MS in the United States was approximately two to one. By 2000, that ratio had grown to approximately four to one.

A role for a microRNA in the immune system has been shown by study of one of the world’s first microRNA knockout mouse. The microRNA acts as a lynchpin to balance the response of immune defences and the researchers suggest the corresponding human gene will have a similar vital role.