Body

Arctic sea ice is melting at a significantly faster rate than projected by even the most advanced computer models, a new study concludes.

Among flagship species for conservation, Lonesome George is perhaps the most renowned. Long thought to be the sole survivor of a species of giant Galápagos tortoise (Geochelone abingdoni), this conservation icon may not be alone for much longer. Researchers headed by investigators at Yale University report these findings in work published online on April 30th in the journal Current Biology.

The heart is one of the most energy demanding organs of the human body. Its failure to function properly accounts for 600,000 deaths each year. Similarly, the rainbow trout, native to the Pacific Northwest and beloved as a sport- and food fish, requires dynamic and sustained cardiac function to maintain its health and swimming activity.

A recent describes a new agent, called "Zorro-LNA," which has the potential to stop genetic disorders in their tracks. In the study, researchers from the Karolinska Institute in Stockholm, Sweden, describe how they developed Zorro-LNA to bind with both strands of a gene’s DNA simultaneously, effectively disabling that gene.

Fish oil, it's been touted as an answer to Alzheimers, arthritis and even weight-loss but now a Queensland University of Technology researcher will test its health benefits in people with chronic kidney disease.

Dietitian Rachel Zabel, from QUT's Institute of Health and Biomedical Innovation in Brisbane, Australia, will investigate the effects of fish oil on patients with kidney disease undergoing dialysis.

Ms Zabel said daily doses of fish oil in the form of a tablet or liquid had been shown to decrease inflammation - a common problem in people with kidney disease.

Recent data from the Lung Allograft Rejection Gene expression Observational (LARGO) study provides compelling evidence that profiling gene expression in peripheral blood can detect organ rejection in lung transplant patients.

Research shows that adolescents who engage in one form of risky behavior, like drug or alcohol use, are likely to engage in other risky behaviors like self-harm, or having unprotected sex, but often times these behaviors are not discussed during a medical or mental health exam. Now, a new study shows that a simple and brief screening measure called the adolescent risk inventory (ARI) can quickly identify the broad range of risk behaviors found among adolescents.

Tart cherries may be good for more than just making pie, according to new data from an animal study conducted by University of Michigan Health System researchers and presented today at a major scientific meeting.

Increasing intake of antioxidant-rich cherries may help lower the risk of metabolic syndrome and cardiovascular disease, suggests a new study(1) presented today at the Experimental Biology annual meeting.

Researchers say the animal study is encouraging and will lead to further clinical studies in humans.

Dr. Yijun Qi (National Institute of Biological Sciences, China), reports his discovery of microRNAs in the unicellular green alga, Chlamydomonas reinhardtii. This is the first finding of microRNAs in a unicellular organism.

“The finding changes the dogma that miRNAs only exist in multicellular organisms, and adds an important piece into the blooming small RNA world. A pressing question we have now is what these miRNAs are exactly doing in the green alga. I hope we will know the answers soon,” says Dr. Qi.

Triptolide is derived from a Chinese medicinal herb, named Lei Gong Teng, which has been used in traditional medicine to treat cancer, inflammation, and auto-immune diseases and, more recently, also has been tested in Phase I clinical trials as an anti-tumor agent.

By giving ordinary adult mice a drug - a synthetic designed to mimic fat - Salk Institute scientist Dr. Ronald M. Evans is now able to chemically switch on PPAR-d, the master regulator that controls the ability of cells to burn fat. Even when the mice are not active, turning on the chemical switch activates the same fat-burning process that occurs during exercise. The resulting shift in energy balance (calories in, calories burned) makes the mice resistant to weight gain on a high fat diet.

Northwestern University scientist Mary J.C. Hendrix and colleagues discovered that aggressive melanoma cells (but not normal skin cells nor less aggressive melanoma cells) contain specific proteins similar to those found in embryonic stem cells. This groundbreaking work led to the first molecular classification of malignant melanoma and may help to explain how, by becoming more like unspecialized stem cells, the aggressive melanoma cell gained enhanced abilities to migrate, invade and metastasize while virtually undetected by the immune system.

Some plants need a partner to reproduce. Pollen from one plant pollinates the stigma of another, and a seed is formed. But other plants can self-pollinate, a handy survival mechanism for a lonely plant.

A new study, led by Felix Aigner, M.D., has identified a protein known as Lipocalin-2 (Lcn-2) as potentially responsible for regulating the body's inflammatory response during heart transplants.