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As part of a laboratory experiment, Rebecca Holmes examined water bottles that had been acquired from abroad expecting to find bisphenol A (BPA), a human-made component commonly found in polycarbonate plastics used to make consumer products.

What she found, however, was that those water bottles were just fine, yet some control bottles purchased in the United States and supposedly BPA-free actually contained traces of the chemical now thought to negatively impact heart health.

FINDINGS

A UCLA-led study shows that physicians frequently order preventive medical services for adult Medicare beneficiaries that are considered unnecessary and of "low value" by the U.S. Preventive Services Task Force -- at a cost of $478 million per year.

The researchers analyzed national survey data over a 10-year period, looking specifically at seven preventive services given a "D" rating by the task force, and discovered that these services were ordered more than 31 million times annually.

BACKGROUND

ITHACA, N.Y. - Though more than 131 million Americans have received at least one dose of COVID-19 vaccine to date, public confusion and uncertainty about the importance of second doses and continued public health precautions threaten to delay a U.S. return to normalcy, according to Cornell-led research published April 28 in the New England Journal of Medicine.

When they go to the dentist to get a tooth pulled or another procedure, patients might not think that the prescription they receive to ease their pain could put them or their family at risk of an opioid overdose.

But a new study from the University of Michigan shows that overdose rates were two and a half times higher among patients who filled a prescription for an opioid medication after a dental procedure, compared with those who didn't fill such a prescription.

Exposure before birth to persistent organic pollutants (POPs)-- organochlorine pesticides, industrial chemicals, etc.--may increase the risk in adolescence of metabolic disorders, such as obesity and high blood pressure. This was the main conclusion of a study by the Barcelona Institute for Global Health (ISGlobal), a research centre supported by the "la Caixa" Foundation. The study was based on data from nearly 400 children living in Menorca, who were followed from before birth until they reached 18 years of age.

WASHINGTON, D.C., (April 28, 2021) - The latest, comprehensive data from The North American COVID-19 Myocardial Infarction (NACMI) Registry was presented today as late-breaking clinical research at the Society for Cardiovascular Angiography & Interventions (SCAI) 2021 Scientific Sessions. Results reveal in these series of STEMI activations during the COVID era, patients who tested positive for COVID-19 were less likely to receive diagnostic angiograms. Those with COVID-19 positive status had higher in-hospital mortality.

WASHINGTON, D.C, (April 28, 2021) - An analysis of the prospective Fuwai PCI Registry, confirms long-term dual antiplatelet therapy (DAPT) is an optimal treatment option for acute coronary syndrome patients (ACS) following a percutaneous coronary intervention (PCI). The study shows long-term DAPT reduces ischemic events without increasing bleeding or other complications as compared to short-term DAPT treatments. The study was presented today as late-breaking clinical research at the Society for Cardiovascular Angiography &Interventions (SCAI) 2021 Scientific Sessions.

The research team led by Prof. WENG Jianping from University of Science and Technology of China (USTC) of the Chinese Academy of Sciences has implemented a comprehensive preconception-to-pregnancy management plan, namely CARNATION study, for women with type1 diabetes (T1D), to reduce the risks of adverse pregnancy outcomes and improve the pregnancy care since 2015. The study was published in Diabetes Care.

ATLANTA--Processed diets, which are low in fiber, may initially reduce the incidence of foodborne infectious diseases such as E. coli infections, but might also increase the incidence of diseases characterized by low-grade chronic infection and inflammation such as diabetes, according to researchers in the Institute for Biomedical Sciences at Georgia State University.

Children and young adults with compromised immune systems, such as those undergoing cancer treatment, may experience a prolonged period of infection with SARS-CoV-2, the virus that causes COVID-19, and the extended duration of infection may increase the incidence of mutations. This case study was conducted by investigators at Children's Hospital Los Angeles and is published in the journal EBioMedicine.

Philadelphia, April 28, 2021 - Researchers from the Center for Autism Research (CAR) at Children's Hospital of Philadelphia (CHOP) found that difficulties in diagnosing toddlers with autism spectrum disorder (ASD) might be due to the dynamic nature of the disorder during child development. Children with clinical characteristics that put them on the diagnostic border of autism have an increased susceptibility to gaining or losing that diagnosis at later ages. The findings were published online by The Journal of Child Psychology and Psychiatry.

ROCHESTER, Minn. -- Difficult-to-treat, chronic wounds in preclinical models healed with normal scar-free skin after treatment with an acellular product discovered at Mayo Clinic. Derived from platelets, the purified exosomal product, known as PEP, was used to deliver healing messages into cells of preclinical animal models of ischemic wounds. The Mayo Clinic research team documented restoration of skin integrity, hair follicles, sweat glands, skin oils and normal hydration.

NEW YORK, NY-- Diagnosing chronic kidney disease, which is often undetected until it causes irreversible damage, may soon become automated with a new algorithm that interprets data from electronic medical records.

The algorithm, developed by researchers at Columbia University Vagelos College of Physicians and Surgeons, automatically scours a patient's electronic medical record for results of blood and urine tests and, using a mix of established equations and machine learning to process the data, can alert physicians to patients in the earliest stages of chronic kidney disease.

WINSTON-SALEM, NC - April 27, 2021 -- An intestinal bowel disease that affects up to 10 percent of premature infants at a very vulnerable and developmentally crucial time can lead to serious infection and death. Scientists at the Wake Forest Institute for Regenerative Medicine (WFIRM) are tackling the disease with a human placental-derived stem cell (hPSC) therapy strategy that is showing promising results.