Body
FINDINGS
A new study by researchers at the UCLA Jonsson Comprehensive Cancer Center has identified a novel combination therapy to potentially help overcome resistance to immunotherapy in people diagnosed with advanced lung cancer. The combination approach uses immune checkpoint inhibitors with ATRA, a safe medication that is widely used to treat leukemia. The team found the combination therapy led to eradication of over 70% of tumors when tested in mice with LKB1-deficient lung cancer. It also generated durable tumor-specific immunity.
BACKGROUND
May 4, 2021 - From the very beginning of the AIDS epidemic in 1981, nurses have been at the forefront of patient care, advocacy, and research. But even in the age of antiretroviral therapy and pre-exposure prophylaxis, many challenges remain in reducing the impact of HIV and AIDS, according to the special May/June issue of The Journal of the Association of Nurses in AIDS Care (JANAC).
WASHINGTON, DC -- A new case report, detailed in Annals of Emergency Medicine, is the first known case of a patient with VITT (vaccine-induced thrombotic thrombocytopenia) treated with a heparin alternative following the Centers for Disease Control and Prevention (CDC) guidance.
ROCHESTER, Minn. -- A pair of Mayo Clinic studies shed light on something that is typically difficult to see with the eye: respiratory aerosols. Such aerosol particles of varying sizes are a common component of breath, and they are a typical mode of transmission for respiratory viruses like COVID-19 to spread to other people and surfaces.
A new USC study suggests that certain neighborhoods - particularly those characterized by poverty and unemployment - may pose an environmental risk to the developing brains of children, impacting neurocognitive performance and even brain size.
The research was published May 3 in the journal JAMA Pediatrics.
A state of the art plenary session during the Pediatric Academic Societies (PAS) 2021 Virtual Meeting discussed prenatal environmental contaminants and childhood disease, and the latest evidence for epigenetic mechanisms associated with transgenerational disease and public policy implications.
CLEVELAND, Ohio (May 5, 2021)--Vitamin D is a critical part of a healthy diet. Among other benefits, it has been shown to protect against bone disease and maintain soft tissue health. A new study suggests that it may also play a role in the degree of postoperative pain postmenopausal women experience after undergoing total knee replacement. Study results are published online today in Menopause, the journal of The North American Menopause Society (NAMS).
A new study published in Arthritis Care & Research indicates that few individuals with the autoimmune disease lupus who were publicly insured through Medicaid received recommended vaccines in 2000-2010. Also, those who were unvaccinated needed more acute care for vaccine-preventable illnesses.
Untreated mental health disorders can be a serious problem for women and their children during pregnancy and after giving birth, during the postpartum period. A recent analysis funded by the Agency for Healthcare Research and Quality (AHRQ) and published in Psychiatric Research & Clinical Practice notes that few studies have examined the benefits of medications for mental health disorders in pregnant and postpartum women.
Erythropoietin (EPO) is a medication used to stimulate the production of new red blood cells, which is impaired in individuals with kidney failure. Unfortunately, however, the treatment may increase the risk of hip fractures.
An analysis of published studies indicates that Twitter may be a useful learning tool in dental education.
A study involving researchers at Karolinska Institutet and Gothenburg University in Sweden has found that low levels of a protein called PDGFRb are associated with particularly good results of radiotherapy in women with early-stage breast cancer. The study, which is published in the journal Clinical Cancer Research, also suggests that the efficacy of radiotherapy can be improved with drugs that block this protein.
On September 28, 2018, an inexplicably large tsunami devastated the Indonesian coastal city of Palu and several others nearby. Between the tsunami and the magnitude 7.5 earthquake that caused it, some 4,340 people were killed, making it the deadliest earthquake that year.
A study published today in Nature Communications shows that the drug rucaparib has been effective in treating certain types of ovarian cancers if used early in treatment, after a diagnosis, and before the cancer cells build up a resistance to chemotherapy.
Nearly one in five older adults say their mental health has gotten worse since the pandemic began in March 2020, and an equal percentage say their sleep has suffered in that time too. More than one in four say they're more anxious or worried than before the COVID-19 era, according to a new poll of people age 50 to 80.