Body

Researchers in France have uncovered a mechanism which explains how biological clocks accurately synchronize to the day/night cycle despite large fluctuations in light intensity during the day and from day to day. Following the identification of two central "clock genes" of a green alga, Ostreococcus tauri, a mathematical model reproducing their daily activity profiles has revealed that their internal clock is influenced by the naturally varying light levels throughout the day only at periods when it needs resetting.

New vaccine hope in fight against pneumonia and meningitis

A new breakthrough in the fight against pneumonia, meningitis and septicaemia has been announced today by scientists in Dublin and Leicester.

The discovery will lead to a dramatic shift in our understanding of how the body's immune system responds to infection caused by Streptococcus pneumoniae and pave the way for more effective vaccines.

Paris, France—The international scientific community has identified five Grand Challenges that, if addressed in the next decade, will deliver knowledge to enable sustainable development, poverty eradication, and environmental protection in the face of global change. The Grand Challenges for Earth system science, published today, are the result of broad consultation as part of a visioning process spearheaded by the International Council for Science (ICSU) in cooperation with the International Social Science Council (ISSC).

URBANA – A University of Illinois metabolic engineer has improved a strain of E. coli, making it grow faster. Don't worry, he believes his efforts will benefit human health, not decimate it.

"The average person hears E. coli and thinks of E. coli 0157:H7, a microorganism that causes horrific food poisoning, but we've developed a strain of E. coli that is suitable for mass production of high-quality DNA that could be used in vaccines or gene therapy," said Yong-Su Jin, a U of I assistant professor of microbial genomics and a faculty member in its Institute for Genomic Biology.

OAK BROOK, Ill. – November 11, 2010 – A new study from researchers in Colorado shows that women offered a female endoscopist were not more likely to undergo a screening colonoscopy than those who were not offered this choice. Past surveys have shown preferences for female endoscopists seem to be common among women. In this study, a patient outreach program failed to support the notion that rates of screening colonoscopy can be increased by offering women the option of a screening colonoscopy performed by a female endoscopist.

CAMBRIDGE, Mass. — Cat fanciers everywhere appreciate the gravity-defying grace and exquisite balance of their feline friends. But do they know those traits extend even to the way cats lap milk?

Researchers at MIT, Virginia Tech and Princeton University analyzed the way domestic and big cats lap and found that felines of all sizes take advantage of a perfect balance between two physical forces. The results will be published in the November 11 online issue of the journal Science.

PHILADELPHIA—An international team of scientists, including a leading evolutionary biologist from the Academy of Natural Sciences, have reset the agenda for future research in the highly diverse Amazon region by showing that the extraordinary diversity found there is much older than generally thought.

ANN ARBOR, Mich.---Strategies for preventing the spread of whooping cough---on the rise in the United States and several other countries in recent years---should take into account how often people in different age groups interact, research at the University of Michigan suggests.

The findings appear in the Nov. 12 issue of the journal Science.

CORVALLIS, Ore. – A new field study confirms that an invasive weed called medusahead has growth advantages over most other grass species, suggesting it will continue to spread across much of the West, disrupt native ecosystems and make millions of acres of grazing land almost worthless.

The research, by scientists from Oregon State University and the Agricultural Research Service, was one of the most comprehensive studies ever done that compared the "relative growth rate" of this invasive annual grass to that of other competing species in natural field conditions.

UCSD researchers create autistic neuron model

Using induced pluripotent stem cells from patients with Rett syndrome, scientists at the University of California, San Diego School of Medicine have created functional neurons that provide the first human cellular model for studying the development of autism spectrum disorder (ASD) and could be used as a tool for drug screening, diagnosis and personalized treatment.

Boston, Mass. - While it has become clear in recent years that susceptibility to pain has a strong inherited component, very little is known about actual "pain genes" and how they work. In the November 12th issue of Cell, researchers at Children's Hospital Boston and their collaborators report on a novel human pain gene. People with minor variations in this gene showed clear differences in susceptibility to acute heat pain and chronic back pain. Corroborating mouse studies give some clues as to how the gene controls pain sensitivity.

"The biggest surprise to me was that we could rescue the autistic phenotype [in the human cells] to something close to normal," said Alysson Muotri of the University of California San Diego.

The researchers made the discovery by first transforming adult cells taken from patients with Rett Syndrome into induced pluripotent stem cells (iPS cells) using an established cocktail. iPS cells look and act very much like embryonic stem cells.

WINSTON-SALEM, N.C. – Thursday, Nov. 11, 2010 – Arsenic, a toxic compound with a reputation as a good tool for committing homicide, has a significant positive effect on the survival of patients with acute promyelocytic leukemia (APL), when administered after standard initial treatment, according to a new, multi-center study led by a researcher at Wake Forest University Baptist Medical Center.

Common diabetes drug may halt growth of cysts in polycystic kidney disease

INDIANAPOLIS – Researchers report that a drug commonly used to treat diabetes may also retard the growth of fluid-filled cysts of the most common genetic disorder, polycystic kidney disease. PKD does not discriminate by gender or race and affects one in 1,000 adults worldwide.