Body

COLUMBUS, Ohio – The genes we possess not only determine the color of our eyes and hair and how our bodies grow, they might also influence the changes that occur in tumors when we develop cancer.

A study by researchers at the Ohio State University Comprehensive Cancer Center-Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) suggests that our normal genetic background – the genetic variations that we inherit – contributes to the kinds of DNA changes that occur in tumor cells as cancer develops.

A University of Colorado at Boulder-led study shows that specific types of stem cells transplanted into the leg muscles of mice prevented the loss of muscle function and mass that normally occurs with aging, a finding with potential uses in treating humans with chronic, degenerative muscle diseases.

ANN ARBOR, Mich. —A diagnosis of idiopathic pulmonary fibrosis is not much better than a death sentence, given a survival rate averaging 4 to 6 years as the disease robs its victim of the ability to breathe.

But researchers at the University of Michigan have discovered a receptor in the immune system that may serve as a marker for a rapidly progressing form of the disease, which causes the body to produce excess fibrous tissue in the lungs.

CORVALLIS, Ore. – There may be many similarities between the importance of large predators in marine and terrestrial environments, researchers concluded in a recent study, which examined the interactions between wolves and elk in the United States, as well as sharks and dugongs in Australia.

AURORA, Colo. (Nov. 10, 2010) – New research released today takes a look at birth outcomes and maternal smoking, building urgency for more states and cities to join the nationwide smoke-free trend that has accelerated in recent years. According to the new data, strong smoke-free policies can improve fetal outcomes by significantly reducing the prevalence of maternal smoking.

DNA repair protein caught in act of molecular theft

Scientists have observed, for the first time, an intermediate stage in the chemical process that repairs DNA methylation damage and regulates many important biological functions that impact health conditions such as obesity, cancer and diabetes.

PROVIDENCE, R.I. [Brown University] — When a foreign object such as a catheter enters the body, bacteria may not only invade it but also organize into a slick coating — a biofilm — that is highly resistant to antibiotics. Like sophisticated organized crime rings, biofilms cannot be defeated by a basic approach of conventional means. Instead doctors and drug developers need sophisticated new intelligence that reveals the key players in the network and how they operate.

(Garrison, NY) Organizations that seek to provide health care, food, and other services to people held in drug detention centers in developing countries often face ethical dilemmas: Are they doing more good than harm? Are they helping detainees or legitimizing a corrupt system and ultimately building its capacity to detain and abuse more people?

Michael Mengel, a pathology researcher with the Faculty of Medicine & Dentistry, has found a new way to analyze biopsies from heart transplant patients by looking at their genes. This allows him to make an early prediction whether the transplant is working.

This is extremely important in heart transplant patients because a successful outcome depends completely on doing a biopsy of the heart tissue and prescribing treatments if necessary. In other organs transplants, doctors can use other measurements.

The seeds that you plant in your backyard garden next spring — and farmers sow in their fields — may have a guardian angel that helps them sprout, stay healthy, and grow to yield bountiful harvests. It's a thin coating of chemicals termed a "seed treatment" that can encourage seeds to germinate earlier in the season, resist insects and diseases, and convey other advantages. These new seed defenders are the topic of an article in the current issue of Chemical & Engineering News (C&EN), ACS' weekly newsmagazine.

GM, Chrysler bankruptcies created troubling legacy, legal scholars say

CHAMPAIGN, Ill. — The Chrysler and General Motors bankruptcy reorganizations represented a sea change in corporate restructuring, one that could portend the end of our current system of bankruptcy reorganization, according to a published article by two University of Illinois experts in bankruptcy law.

Experiments with an artificial stomach suggest that a popular lemon-lime soft drink could play an unexpected role in improving the effectiveness of an oral anticancer drug. The experiments produced evidence that patients will absorb more of the unnamed drug, tested in Phase I in clinical trials, when taken with "flat" or degassed Sprite. The study appears in ACS' Molecular Pharmaceutics, a bi-monthly journal.

November 10, 2010 -- To keep soldiers in the battlefield healthy, the U.S. Army is exploring new ways to detect harmful bacteria in water.

Current techniques for analyzing water in the field can take as long as 24 hours to complete, according to Bart Lipkens of Western New England College in Springfield, Massachusetts and his colleagues at Physical Sciences in Andover, Ma.

They are working on an alternative technology that uses sound waves to accelerate the process.

New hemlock hybrids that are tolerant to the invasive insect known as hemlock woolly adelgid have been created by U.S. Department of Agriculture (USDA) scientists.