DURHAM, N.C. – Pathogenic fungi have been found to protect themselves against unwanted genetic mutations during sexual reproduction, according to researchers at Duke University Medical Center. A gene-silencing pathway protects the fungal genome from mutations imposed by a partner during mating.
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MADISON – Growing human embryonic stem cells in the lab is no small feat. Culturing the finicky, shape-shifting cells is labor intensive and, in some ways, more art than exact science.
Now, however, a team of researchers at the University of Wisconsin-Madison reports the development of a fully defined culture system that promises a more uniform and, for cells destined for therapy, safer product.
In today's world of sophisticated organisms proteins are the stars. They are the indispensible catalytic workhorses, carrying out the processes essential to life. But long, long ago ribonucleic acid (RNA) reigned supreme.
Now Northwestern University researchers have produced an atomic picture that shows how two of these very old molecules interact with each other. It is a rare glimpse of the transition from an ancient, RNA-based world to our present, protein-catalyst dominated world.
Scientists studying genetic data from nearly 50,000 people have uncovered several DNA sequence variations associated with the electrical impulses that make the heart beat. The findings, reported in Nature Genetics, may pave the way for a greater understanding of the mechanisms for abnormal heart rhythms and sudden cardiac death.
Light to moderate alcohol consumption (about two to three drinks daily) among male coronary artery bypass patients was associated with 25 percent fewer subsequent cardiovascular procedures, heart attacks, strokes and death compared to non-drinkers, in a study presented at the American Heart's Association's Scientific Sessions 2010.
However, bypass patients with left ventricular dysfunction who were moderate to heavy drinkers (more than six drinks daily) were twice as likely to have subsequent cardiovascular deaths compared to non-drinkers.
The death of a spouse or child can cause elevated heart rate and other potentially harmful heart rhythm changes among the recently bereaved, according to research presented at the American Heart Association's Scientific Sessions 2010.
These changes in how the heart functions — which could increase the risk of heart attack and sudden cardiac death — tend to revert back to normal ranges within six months, researchers said.
While vitamin D deficiency is associated with fatal stroke among whites, it is not linked to more stroke deaths among blacks, according to research presented at the American Heart Association's Scientific Sessions 2010.
Analyzing the health records of a nationally representative group of 7,981 black and white adults, researchers found that whites with deficient vitamin D levels had a doubled risk of dying from a stroke compared to whites with higher vitamin D levels.
Women who report having high job strain have a 40 percent increased risk of cardiovascular disease, including heart attacks and the need for procedures to open blocked arteries, compared to those with low job strain, according to research presented at the American Heart Association's Scientific Sessions 2010.
A protocol that uses continuous real-time radiation monitoring, low-dose imaging programs and requires physician awareness of radiation dose, significantly reduced radiation exposure during electrophysiology procedures and catheter ablations to diagnose and treat heart arrhythmias in children, according to research presented at the American Heart Association's Scientific Sessions 2010.
Invasive cardiac electrophysiology is used to diagnose and treat abnormal heart rhythms, or arrhythmias, which can range from the benign to the life-threatening.
The proportion of adult smokers dramatically decreased during the past three decades in at least one metropolitan area — with more quitting and fewer picking up the habit, according to research presented at the American Heart Association's Scientific Sessions 2010.
Eating smaller amounts of salt each day as a teenager could reduce high blood pressure, heart disease and stroke in adulthood, according to research presented at the American Heart Association's Scientific Sessions 2010.
Conducting a sophisticated computer modeling analysis, researchers projected the nationwide health effects of a 3-gram reduction in dietary salt from processed foods consumed by adolescent boys and girls.
People who sleep poorly or do not get enough sleep have higher levels of inflammation, a risk factor for heart disease and stroke, researchers have found.
Data from a recent study are scheduled to be presented Sunday, Nov. 14 at the American Heart Association Scientific Sessions in Chicago by Alanna Morris, MD, a cardiology fellow at Emory University School of Medicine.
OTTAWA – November 14, 2010 – One of the largest, most extensive worldwide investigations into heart failure, led by the University of Ottawa Heart Institute (UOHI), conclusively proves that a new therapeutic implant synchronizes and strengthens a fading heart beat while reducing risk of death by 24% compared to the current treatment.
WASHINGTON, Nov. 13, 2010 — With chitlins about to make their annual appearance on Thanksgiving, Christmas, and New Year's Day menus, scientists have good news for millions of people who love that delicacy of down-home southern cooking, but hate the smell. They are reporting the first identification of an ingredient in cilantro that quashes the notoriously foul odor of chitlins — a smell known to drive people from the house when chitlins are cooking. Their report appears in ACS' Journal of Agricultural and Food Chemistry.
An examination of the heritability of atrial fibrillation (AF) among more than 4,000 participants in the Framingham Heart Study finds the occurrence of AF in first-degree relatives was associated with AF risk after adjustment for established AF risk factors and AF-related genetic variants, according to a study that will appear in the November 24 issue of JAMA. The study is being released early online because it will be presented at the American Heart Association's annual meeting.