Body

Cambridge, Mass. – February 7, 2011 – A team of applied physicists at Harvard's School of Engineering and Applied Sciences (SEAS), Princeton, and Brandeis have demonstrated the formation of semipermeable vesicles from inorganic clay.

The research, published online this week in the journal Soft Matter, shows that clay vesicles provide an ideal container for the compartmentalization of complex organic molecules.

The authors say the discovery opens the possibility that primitive cells might have formed inside inorganic clay microcompartments.

It is widely known that fruit contains antioxidants which may be beneficial to health. New research published in the open access journal Chemistry Central Journal demonstrates that chocolate is a rich source of antioxidants and contains more polyphenols and flavanols than fruit juice.

When researchers at the Hershey Center for Health & Nutrition™ compared the antioxidant activity in cocoa powder and fruit powders they found that, gram per gram, there was more antioxidant capacity, and a greater total flavanol content, in the cocoa powder.

Crested gibbons (genus Nomascus) live in dense Asian rainforest, specifically in China, Laos, Cambodia and Vietnam, and, because of their environment, they communicate with other gibbons by singing. Both males and females sing in order to define territory and find a mate, and couples also sing duets to strengthen their pair bonding. New research published in BioMed Central's open access journal BMC Evolutionary Biology describes how gibbon song can be used to identify not only which species of Gibbon is singing but the area it is from.

Kyoto, Japan -- In a complex feat of nanoengineering, a team of scientists at Kyoto University and the University of Oxford have succeeded in creating a programable molecular transport system, the workings of which can be observed in real time. The results, appearing in the latest issue of Nature Nanotechnology, open the door to the development of advanced drug delivery methods and molecular manufacturing systems.

A team of researchers, led by University of Kentucky ophthalmologist Dr. Jayakrishna Ambati, has discovered a molecular mechanism implicated in geographic atrophy, the major cause of untreatable blindness in the industrialized world.

Their article, "DICER1 Deficit Induces Alu RNA Toxicity in Age-Related Macular Degeneration," was published online by the journal Nature on Feb. 6 (DOI: 10.1038/nature09830).

An international team of researchers has made new links between 29 regions of the genome and ulcerative colitis – a common form of inflammatory bowel disease (IBD). The new findings increase the total number of genome regions known to be associated with inflammatory bowel disease to 99.

The results point to several biological processes, including the way that our bodies maintain the lining of the intestinal wall, which are likely to play an important role in the development of ulcerative colitis.

The first genome-wide study to demonstrate an inherited genetic basis for racial and ethnic disparities in cancer survival linked Native American ancestry with an increased risk of relapse in young leukemia patients. The work was done by investigators at St. Jude Children's Research Hospital and the Children's Oncology Group (COG).

WASHINGTON, Feb. 5, 2011 — With millions of people warding off winter's chill with blazing fireplaces and wood-burning stoves, scientists are raising red flags about the potential health effects of the smoke released from burning wood. Their study, published in the American Chemical Society's (ACS') journal, Chemical Research in Toxicology, found that the invisible particles inhaled into the lungs from wood smoke may have several adverse health effects. It is among 39 peer-reviewed scientific journals published by ACS, the world's largest scientific society.

CHICAGO --- Small calf muscles may be a feminine trait, but for women with peripheral artery disease (PAD) they're a major disadvantage. Researchers at Northwestern Medicine point to the smaller calf muscles of women as a gender difference that may cause women with PAD to experience problems walking and climbing stairs sooner and faster than men with the disease.

The study was published in the February 2011 issue of the Journal of the American College of Cardiology.

Since the days of Darwin, the "tree of life" has been the preeminent metaphor for the process of evolution, reflecting the gradual branching and changing of individual species.

The discovery that a large cluster of genes appears to have jumped directly from one species of fungus to another, however, significantly strengthens the argument that a different metaphor, such as a mosaic, may be more appropriate.

An ambitious hunt by Johns Hopkins scientists for actively "jumping genes" in humans has yielded compelling new evidence that the genome, anything but static, contains numerous pesky mobile elements that may help to explain why people have such a variety of physical traits and disease risks.

The vaccine for human papillomavirus (HPV) can prevent 90 percent of genital warts in men when offered before exposure to the four HPV strains covered by the vaccine, according to a new multi-center study led by H. Lee Moffitt Cancer Center and UCSF.

The four-year, international clinical trial, which also found a nearly 66 percent effectiveness in the general population of young men regardless of prior exposure to these strains, provides the first reported results of using the HPV vaccine as a prophylactic in men.

Things are not always what they seem when it comes to fish—something scientists at the Smithsonian Institution and the Ocean Science Foundation are finding out. Using modern genetic analysis, combined with traditional examination of morphology, the scientists discovered that what were once thought to be three species of blenny in the genus Starksia are actually 10 distinct species. The team's findings are published in the scientific journal ZooKeys, Feb. 3.

CHAPEL HILL, N.C. – Everyone knows chocolate is critical to a happy Valentine's Day. Now scientists are one step closer to knowing what makes a heart happy the rest of the year.

It's a gene called DOT1L, and if you don't have enough of the DOT1L enzyme, you could be at risk for some types of heart disease. These findings from a study led by researchers at the University of North Carolina at Chapel Hill School of Medicine appear in the Feb. 1, 2011 issue of the journal Genes and Development.

Rainer Kube and his working group report in the current issue of Deutsches Ärzteblatt International (Dtsch Arztebl Int 2011; 108[4]: 41-6) on new treatment strategies in patients with colon cancer.