A team of researchers at the University of Gothenburg, Sweden, has identified an enzyme that protects against inflammation and joint destruction. Made when the researchers blocked production of the enzyme GGTase-I in transgenic mice, this unexpected discovery could lead to the identification of new mechanisms that control the development of inflammatory disorders, as well as new medicines.
Body
After analyzing hundreds of proteins produced by the DNA of tumor cells, researchers have identified one protein that may be central to a new treatment for the often-fatal childhood cancer neuroblastoma. Oncologists hope to translate the finding into pediatric clinical trials of a drug that blocks the protein's activity.
In the first study to examine the response to noise of a diverse range of crustaceans, an international team led by the University of Bristol found that many families of crustaceans previously assumed to be deaf could detect, and avoid, reef noise.
How long your parents lived does not affect how long you will live. Instead it is how you live your life that determines how old you will get, reveals research from the University of Gothenburg recently published in the Journal of Internal Medicine.
It is often assumed that people with parents who lived to be very old are more likely to live to a grand old age themselves.
CHAMPAIGN, Ill. — In two new works, an anthropologist tackles a perplexing question relating to the enormously successful "Body Worlds" exhibits: How does society tolerate – and even celebrate – the public display of human corpses?
Using mathematical concepts, Princeton researchers have developed a method of discovering new drugs for a range of diseases by calculating which physical properties of biological molecules may predict their effectiveness as medicines.
The technique already has identified several potential new drugs that were shown to be effective for fighting strains of HIV by researchers at Johns Hopkins University.
Two new sources of soybean meal are capturing attention throughout the country. University of Illinois research indicates that fermented soybean meal and enzyme-treated soybean meal may replace fish meal in weanling pig diets.
"The price of fish meal has exploded and is causing producers to search for new options for weanling pig diets," said Hans H. Stein, U of I professor of animal sciences. "Pigs are traditionally fed diets containing relatively large amounts of animal proteins such as fish meal from weaning up to 40 pounds when they can digest traditional soybean meal."
Patients with kidney tumours larger than four centimetres are much more likely to enjoy good long-term renal function if they undergo nephron-sparing surgery rather than radical nephrectomy, according to a study in the February issue of the urology journal BJUI.
Researchers from the Department of Urology at Johannes Gutenberg University in Mainz, Germany, studied 166 patients for up 19 years, with a median follow up of five-and-a-half years. The participants were split into two groups - 81 "younger" patients up to 55 and 85 "older" patients aged 65 and over.
Jerusalem, February 7, 2011 -- A low cost, nanometer-sized drug to treat chronic wounds, such as diabetic foot ulcers or burns, has been developed by a group of scientists from the Hebrew University of Jerusalem, Harvard Medical School and others in the U.S. and Japan.
Diabetes is a rapidly growing medical problem affecting close to 3 percent of the world's population. Poor blood circulation arising from diabetes often results in skin wounds which do not heal, causing pain, infection and at times amputation of limbs.
Acupuncture and physical exercise improve hormone levels and menstrual bleeding pattern in women with polycystic ovary syndrome (PCOS), reveals research from the University of Gothenburg, Sweden.
Kyoto, Japan -- Unprecedented single molecule imaging movies of living cell membranes, taken by a research team based at Kyoto University and the University of New Mexico, have clarified a decades-old enigma surrounding receptor molecule behaviors. The results, appearing in the latest issue of the Journal of Cell Biology, promise to open the door to new possibilities for drug development.
Patients with kidney tumours larger than four centimetres are much more likely to enjoy good long-term renal function if they undergo nephron-sparing surgery rather than radical nephrectomy, according to a study in the February issue of the urology journal BJUI.
Researchers from the Department of Urology at Johannes Gutenberg University in Mainz, Germany, studied 166 patients for up 19 years, with a median follow up of five-and-a-half years. The participants were split into two groups - 81 "younger" patients up to 55 and 85 "older" patients aged 65 and over.
Heartburn is a signature symptom of gastroesophageal reflux disease (GERD), which is a cluster of symptoms and signs associated with regurgitation of stomach acid up to the pharynx and mouth. Patient-based studies of GERD have shown high prevalence and chronicity, particularly in Western societies. GERD is associated with significant health-care utilization and diminished quality of life. Heartburn, coupled with acid regurgitation and painful swallowing are considered to be highly specific for GERD.
Concerning treatment, until recently the only definitive treatment for hydatid disease had been surgery. Different surgical techniques and procedures have been carried out and even in some cases, a liver transplant has been required. Advances in drug therapy has been influenced by the introduction of albendazole and accelerated by addition of praziquantel, but this requires a long period of treatment i.e. up to a year or more, and is not effective for everyone.
The concept of fast track rehabilitation program has been recently introduced in colorectal surgery. It is basically a multidisciplinary perioperative care strategy for patients after resection of colorectal cancer.
A research article to be published on February 7, 2011 in the World Journal of Gastroenterology addresses this question. The authors compared the complications, restoration of gastrointestinal functions, and hospital stay time of postoperative colorectal cancer patients after fast-track rehabilitation program and conventional care.