Grenoble (France) – A novel X-ray imaging technology is helping scientists better understand how in the course of evolution snakes have lost their legs. The researchers hope the new data will help resolve a heated debate about the origin of snakes: whether they evolved from a terrestrial lizard or from one that lived in the oceans. New, detailed 3-D images reveal that the internal architecture of an ancient snake's leg bones strongly resembles that of modern terrestrial lizard legs. The results are published in the 8 February issue of the Journal of Vertebrate Paleontology.
Body
Hibernating, it turns out, is much more complicated than one might think.
Research published in the latest issue of the journal Physiological and Biochemical Zoology illustrates a complex series of changes that occur in grizzly bears' hearts as they hibernate. The changes guard against complications that could arise from greatly reduced activity.
PHILADELPHIA - So-called barrier sites -- the skin, gut, lung – limit the inner body's exposure to allergens, pollutants, viruses, bacteria, and parasites. Understanding how the immune system works in these external surfaces has implications for understanding such inflammatory diseases as asthma, psoriasis, IBD, and food allergies, all of which occur at the body's barriers.
Are you still looking for a date for Valentine's Day? Here's some dating advice straight from the laboratory: It turns out there may be something to "playing hard to get." A study published in Psychological Science, a journal of the Association for Psychological Science, finds that a woman is more attracted to a man when she is uncertain about how much he likes her.
TEMPE, Ariz. – Despite decades of research and billions of dollars, cancer remains a major killer, with an uncanny ability to evade both the body's defenses and medical intervention. Now an Arizona State University scientist believes he has an explanation.
WASHINGTON, Feb. 7, 2011 — In time for the chocolate-giving and chocolate-noshing fest on Valentine's Day, scientists are reporting discovery of how this treat boosts the body's production of high-density lipoprotein cholesterol (HDL) — the "good" form of cholesterol that protects against heart disease. Just as those boxes of chocolates get hearts throbbing and mouths watering, polyphenols in chocolate rev up the activity of certain proteins, including proteins that attach to the genetic material DNA in ways that boost HDL levels.
A digital signal processing technique long used by statisticians to analyze data is helping Houston scientists understand the roots of memory and learning, Alzheimer's and Parkinson's diseases and stroke.
Focused programs and public health policies can help reduce the burden of alcohol in Canada, which contributes significantly to acute and chronic diseases, social problems and trauma, states an analysis in CMAJ (Canadian Medical Association Journal) (pre-embargo link only) http://www.cmaj.ca/embargo/cmaj100825.pdf.
Exposure to low-dose radiation from cardiac imaging and other procedures after a heart attack is associated with an increased risk of cancer, found a new study published in CMAJ (Canadian Medical Association Journal) (pre-embargo link only) http://www.cmaj.ca/embargo/cmaj100463.pdf.
A five-week old infant most likely contracted a vaccine strain of yellow fever virus through breastfeeding, according to a case report published in CMAJ (Canadian Medical Association Journal) (pre-embargo link only) http://www.cmaj.ca/embargo/cmaj100619.pdf
The majority of fatal cases of malaria are caused by infection with the parasite Plasmodium falciparum. Most at risk are young children and women who are pregnant. A team of researchers, led by Patrick Duffy, at the National Institutes of Health, Rockville, has now developed an approach to profile P. falciparum parasites in such a way that they are able to identify parasite genes associated with severe infection.
The bone marrow stem cells responsible for generating new blood cells are less fixed and more flexible than previously thought, according to a paper published online on February 7 in the Journal of Experimental Medicine (www.jem.org).
Using a unique and relatively simple cell-based fluorescent assay they developed, scientists with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC), Berkeley have identified a means by which fluoxetine, the active ingredient in Prozac, suppresses the activity of the TREK1 potassium channel. TREK1 activity has been implicated in mood regulation and could be an important target for fluoxetine and other antidepressant drugs.
Defects in the genome are the cause of many diseases. Gene therapy – direct replacement of mutant genes by intact DNA copies – offers a means of correcting such defects. Now a research team based at the Medical Center of the University of Munich, and led by Privatdozent Dr. Carsten Rudolph, has taken a new approach that avoids DNA delivery. The team shows for the first time that chemical modification of mRNAs (the metabolically active molecules derived from genomic DNA that programs protein synthesis) provides a promising alternative to DNA-based procedures.
Washington, D.C.—Surprising new research shows that, contrary to conventional belief, remains of chitin-protein complex—structural materials containing protein and polysaccharide—are present in abundance in fossils of arthropods from the Paleozoic era. Previously the oldest molecular signature of chitin-protein complex was discovered in 25 million year old Cenozoic fossils and remnants of structural protein have also been discovered in 80 million-year-old Mesozoic fossils.