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Scientists from the Skoltech Center for Energy Science and Technology and the Institute of Problems of Chemical Physics of RAS in collaboration with researchers from four other Russian and foreign research centers have discovered a new reaction that helps obtain water-soluble fullerene derivatives which effectively combat flu viruses, human immunodeficiency virus (HIV), herpes simplex virus (HSV), and cytomegalovirus (CMV).
A new study of men and women with hypersexual disorder has revealed a possible role of the hormone oxytocin, according to results published in the journal Epigenetics. The finding could potentially open the door to treating the disorder by engineering a way to suppress its activity.
PITTSBURGH, Sept. 23, 2019 - In March 2016, the Organ Procurement and Transplantation Network revised its criteria for prioritizing children awaiting heart transplantation in the U.S. with the intention of reducing the number of deaths on the waitlist, but a new study suggests unintended consequences.
A new Canadian guideline lays out the optimal strategies for providing injectable opioid agonist treatment with prescription heroin and hydromorphone for people with severe opioid use disorder. The clinical guideline was created for a wide range of health care providers to address an urgent need for evidence-based treatment of opioid use causing overdose and death, and is published in CMAJ (Canadian Medical Association Journal).
In people with diabetes, fat mass index, not body mass index (BMI), is associated with a higher risk of cardiovascular events, according to new research in CMAJ (Canadian Medical Association Journal).
Opioid use is increasing in pregnancy as well as the general population. A "Five things to know about ..." practice article on opioid disuse in pregnancy in CMAJ (Canadian Medical Association Journal) provides information on how to manage this vulnerable population.
1. Opioid use and opioid use disorders in pregnancy are rising.
2. Guidelines support universal screening for drug use, including opioids, by prenatal care providers.
This release was amended on 26/09/19 to clarify the impact of the research.
Researchers at Chalmers University of Technology, Sweden, have discovered a new aspect to the way that DNA binds itself, and the role played by hydrophobic effects. They show how small changes in water properties can delicately control the binding process. The discovery opens doors for new understanding in research in medicine and life sciences. The researchers’ findings are presented in the journal PNAS.
A drug used to treat chronic myeloid leukemia appears to be more effective at stopping a type of medulloblastoma in mouse models than existing treatments for the deadly pediatric brain tumor, reports a multi-institutional team led by researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego.
WASHINGTON (September 20, 2019) - A new shock classification scheme released by the Society for Cardiovascular Angiography and Interventions (SCAI) and endorsed by the American College of Cardiology (ACC), American Heart Association, the Society of Critical Care Medicine and the Society of Thoracic Surgeons was recently applied in a retrospective study analyzing patients in the cardiac intensive care unit (CICU) at the Mayo Clinic. The study was published today in early view in the Journal of the American College of Cardiology (JACC).
Alexandria, VA, USA - 2019 marks the Centennial of the Journal of Dental Research (JDR). Over the last century the JDR has been dedicated to the dissemination of new knowledge and information on all sciences relevant to dentistry and to the oral cavity and associated structures in health and disease.
To celebrate, the JDR is featuring a yearlong, monthly commemorative article and podcast series that highlights topics that have transformed dental, oral and craniofacial research over the past 100 years.
A key requirement for future facilities that aim to capture and control on Earth the fusion energy that drives the sun and stars is accurate predictions of the pressure of the plasma -- the hot, charged gas that fuels fusion reactions inside doughnut-shaped tokamaks that house the reactions. Central to these predictions is forecasting the pressure that the scrape-off layer, the thin strip of gas at the edge of the plasma, exerts on the divertor -- the device that exhausts waste heat from fusion reactions.
CHAPEL HILL, NC - A new study published today in Nature Communications shows a promising alternative for those who have to take a daily pill regimen. Targeting HIV treatment and prevention, researchers across multiple departments at the University of North Carolina at Chapel Hill collaborated on a seven-year study in animals to make a better injectable drug implant that can combine multiple drugs and is ultra-long-acting, while also addressing many of the challenges faced with current HIV treatment and prevention methods.
A new family of drugs which inhibit the activity of a protein associated with prostate and other cancers has been reported by scientists from the University of Bath.
New research led by the University of South Australia shows just how effective bowel cancer screening is in helping to reduce the number of bowel cancer deaths by up to 45 per cent.
Bowel (or colorectal) cancer kills almost 6000 people in Australia each year and 700,000 worldwide but this number would be much higher without pre-diagnostic colonoscopies, a study has found.
Data from 12,906 bowel cancer patients indicate that faecal occult blood testing (FOBT) with a follow-up colonoscopy plays a key role in catching the disease early, before symptoms appear.
Dengue virus (DENV) infects about 400 million people annually around the world, with a high prevalence in tropical and sub-tropical regions. The virus causes diseases ranging from mild dengue fever to severe dengue haemorrhagic fever and dengue shock syndrome.