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CLEVELAND, Ohio (September 24, 2019)--The Women's Health Initiative (WHI) remains one of the most highly quoted when debating the benefits and risks of hormone therapy. Now a new study based on WHI data demonstrates that, among other benefits, hormone therapy decreases a number of metabolites that are directly linked with Type 2 diabetes. Study results will be presented during The North American Menopause Society (NAMS) Annual Meeting in Chicago, September 25 to 28, 2019.
COLUMBUS, Ohio - A new clinical trial conducted at The Ohio State University Wexner Medical Center found a cost-effective generic medication works just as well as a more expensive drug in preserving cardiovascular function in boys with Duchenne muscular dystrophy (DMD).
Results of this multi-center trial are in today's Journal of the American Heart Association.
OAKLAND, Calif. -- Patients with type 2 diabetes who were in poor health were more likely to continue taking insulin after age 75 than their counterparts in better health, according to Kaiser Permanente research published today in JAMA Internal Medicine. As people with type 2 diabetes age, the risks of insulin use can outweigh its benefits, creating the need for increased provider and patient education.
Researchers at University of California San Diego School of Medicine say they are getting closer to identifying the mechanisms of autism spectrum disorder (ASD) and biomarkers that can aid in early diagnosis and predictions of symptom severity.
A team of scientists analyzed blood gene expression data from 302 one- to four-year-old boys with and without the diagnosis of ASD. They uncovered a critical gene network that is disrupted in ASD, noting that the perturbed gene network is related to fetal brain development and also dysregulated in ASD cellular models.
What The Study Did: This study used enrollment data to examine changes in the internal medicine subspecialty choices of women and men from 1991 to 2016. Data were examined for nine internal medicine subspecialties: cardiovascular disease, endocrinology, gastroenterology, geriatric medicine, hematology and oncology, infectious disease, nephrology, pulmonary disease and critical care, and rheumatology.
After a recent study showed that chronic lymphocytic leukemia patients who received ibrutinib as a frontline treatment had a 7% death rate, a new study offers a clearer picture on the reasons for the deaths.
A team of researchers utilized the VigiBase, a global database of drug complications maintained by the World Health Organization, to analyze deaths associated with ibrutinib, a targeted therapy for several blood cancers that has boosted long-term survival rates and proven superior to other therapies.
Researchers have discovered that gene expression regulators work together to raise an individual's risk of developing schizophrenia. Schizophrenia-like gene expression changes modeled in human neurons matched changes found in patients' brains. The researchers, led by Kristen Brennand, of the Icahn School of Medicine at Mount Sinai, New York City, report on their findings in Nature Genetics. The work was funded by the National Institute of Mental Health (NIMH), part of the National Institutes of Health.
According to recent research, even mild long-term depressive symptoms among mothers are connected with emotional problems among small children such as hyperactivity, aggressiveness and anxiety.
The study investigated how the depressive symptoms of both parents affected the child by the age of two and five.
The father's depressive symptoms affected the child's emotional problems only if the mother was depressed as well. The mother's symptoms, however, affected the child even if the father was not depressed.
Effective diagnosis and treatment of disease draws on painstaking research, which often relies on biological samples. The avalanche of studies used to better understand illnesses and design effective therapies cost billions of dollars and potentially affects millions of lives.
So, it would seem reasonable to assume that the reliability of biological samples, on which accurate results depend, would be of paramount concern for the scientific community.
Research published today in the journal Circulation has found that women with high blood pressure in pregnancy, including conditions such as preeclampsia, have an increased risk of developing cardiovascular disorders later in life, including stroke and heart failure.
An NHS scheme to give every patient aged 75 and over in England a named GP responsible for their care has failed to deliver hoped-for improvements, according to a study by researchers at the University of Bristol's Centre for Academic Primary Care.
The scheme, introduced by the NHS Employers and General Medical Services in April 2014, was designed to improve the care of older people and keep them healthy, independent and out of hospital.
Bethesda, MD (Sept. 23, 2019)-- Diagnosing patients with chronic watery diarrhea can be difficult for health care providers, since several causes with specific therapies, such as inflammatory bowel disease (IBD), microscopic colitis and chronic infection, need to be ruled out.
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The Institute of Medicine's guidelines currently advise all pregnant women to increase calorie intake by 340-450 calories/day during their second and third trimesters, regardless of their body size at conception. Approximately 2/3 of women with obesity at the time of pregnancy will gain more weight than recommended, highlighting a need for evidence-based guidelines to optimize the health of this population and their offspring.
Every year, more than 500,000 children have their tonsils and adenoids surgically removed as a way to treat symptoms related to sleep apnea, making it one of most widely performed pediatric surgical procedures in the United States.