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PORTLAND, Ore. - Hospital patients discharged to skilled nursing facilities often bring a high-dose painkiller prescription with them, suggesting more attention should be paid to opioid safety for those patients, research from the Oregon State University College of Pharmacy shows.
The findings are important because they shed light on an understudied aspect of the opioid-fueled public health crisis that has gripped the United States for more than two decades.
PHILADELPHIA - After looking at the health records of over 10,000 patients with both HIV and multidrug resistant Tuberculosis (TB) in over 20 different countries, researchers at the Perelman School of Medicine at the University of Pennsylvania in collaboration with the Centers for Disease Control and Prevention, McGill University, and other institutions around the world, found that implementing antiretroviral therapy (ART) for HIV and newer tuberculosis medications decreased the risk of death for adults with drug-resistant TB.
DALLAS, August 10, 2020 — Stress-induced activity in the inferior frontal lobe of the brain may have a direct correlation with chest pain among people with coronary artery disease, according to new research released today in Circulation: Cardiovascular Imaging, an American Heart Association journal.
A research group from Tel Aviv University (TAU) successfully reduced metastatic spread following tumor removal surgery in colorectal cancer patients. Using a short medication treatment around the time of the surgery, the researchers were able to reduce body stress responses and physiological inflammation during this critical period, preventing the development of metastases in the years following the surgery.
WASHINGTON - A brain imaging study of veterans with Gulf War illness (GWI) and patients with chronic fatigue syndrome (CFS) (sometimes called myalgic encephalomyelitis), has shown that the two illnesses produce distinctly different, abnormal patterns of brain activity after moderate exercise. The result of the Georgetown University Medical Center study suggests that GWI and CFS are distinct illnesses, an outcome that could affect the treatment of veterans with Gulf War illness.
This summer, children and teens will be spending more time outside. For some, this will include riding all-terrain vehicles (ATVs). Unfortunately, this activity comes with significant risks. A new study conducted by researchers at the Center for Injury Research and Policy and the Department of Otolaryngology-Head and Neck Surgery at Nationwide Children's Hospital analyzed data regarding ATV-related head and neck injuries treated in U.S. emergency departments from 1990 through 2014 involving patients younger than 18 years of age.
Denver--(Embargoed for 7 a.m. EST August 8, 2020)--The interim analysis of ORIENT-11, a phase III double-blind randomized trial has shown a nearly two-fold increase in progression-free survival with addition of sintilimab to chemotherapy in patients with advanced or metastatic non-squamous non-small cell lung cancer without EGFR or ALK genomic aberrations, according to research data presented today at the International Association for the Study of Lung Cancer Virtual Presidential Symposium.
FAIRFAX, Va. -- Endovascular treatment of vein of Galen aneurysmal malformation (VGAM) in babies with severe pulmonary hypertension can improve chances of survival, according to a study released today at the Society of NeuroInterventional Surgery's (SNIS) 17th Annual Meeting.
The study, Outcomes of Endovascular Treatment of Vein of Galen Aneurysmal Malformation in Neonates, evaluated data from 52 surgery patients with VGAMs at the Meshalkin National Medical Research Center. Eleven of these patients were younger than 10 days when surgery was performed.
What The Study Did: The increases and decreases in patient volume and associated changes in treatment experienced by individuals presenting with acute heart attack (myocardial infarction) before and immediately after the onset of the COVID-19 pandemic are examined in this observational study.
Authors: Ty J. Gluckman, M.D., of Providence St Joseph Health in Portland, Oregon, is the corresponding author.
A new approach to predicting which babies will develop type 1 diabetes moves a step closer to routine testing for newborns which could avoid life-threatening complications.
Scientists at seven international sites have followed 7,798 children at high risk of developing type 1 diabetes from birth, over nine years, in The Environmental Determinants of Diabetes in the Young (TEDDY) Study. The TEDDY Study is a large international study funded primarily by the US National Institutes of Health and U.S. Centers for Disease Control, as well as by the charity JDRF.
New Haven, Conn. -- Researchers at the Yale Liver Center found that patients with COVID-19 presented with abnormal liver tests at much higher rates than suggested by earlier studies. They also discovered that higher levels of liver enzymes -- proteins released when the liver is damaged -- were associated with poorer outcomes for these patients, including ICU admission, mechanical ventilation, and death.
The study appeared online on July 29 in Hepatology.
By applying the renewal theory in probability to reduce recall bias in initial case reports, scientists have come up with a new estimate for the incubation period of COVID-19. Their mean estimate of 7.76 days, longer than previous estimates of 4 to 5 days, involves the largest amount of patient samples to date in such an analysis. By providing health authorities with a potentially more accurate figure for the incubation period, the results could inform guidelines for containment efforts such as quarantines and studies investigating the disease's transmission.
Discovering antiviral and anticancer drugs will soon be faster and cheaper thanks to new research from Simon Fraser University chemist Robert Britton and his international team.
For the past 50 years, scientists have used manmade, synthetic and nucleoside analogues to create drug therapies for diseases that involve the cellular division and/or the viral reproduction of infected cells. These diseases include hepatitis, herpes simplex, HIV and cancer.
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UCLA researchers have found that chemotherapy is not commonly used when treating adults with localized sarcoma, a rare type of cancer of the soft tissues or bone. In a nationwide analysis of nearly 20,000 patients whose cancer had not yet spread to other organs, the scientists learned that only 22% were treated with some form of chemotherapy.
Four months ago, Michigan glowed red on COVID-19 maps. Hundreds of patients packed hospital intensive care units in the southern part of the state, and hospitals statewide rapidly put strict new visitor policies in place to slow the spread of the new coronavirus. ICU teams had to scramble to connect with the families of critically ill and dying patients in new ways.