Body
WASHINGTON (Aug. 5, 2020) -- Genetic modifier HDAC6 was found to control tumor growth and halt metastasis in triple-negative breast cancer in vivo, according to a new study published in the top-tier journal Cancer Research by investigators at the George Washington University (GW) Cancer Center.
Immunotherapy - the use of drugs to stimulate one's own immune system to recognize and destroy cancer cells - has been wildly successful in melanoma and other cancers. However, it has been less effective in breast cancer.
What The Study Did: Characteristics and response to treatment of persistent radiation-induced hair loss in patients with primary central nervous system tumors or head and neck cancer were examined in this observational study.
Authors: Mario E. Lacouture, M.D., of Memorial Sloan Kettering Cancer Center in New York, is the corresponding author.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamadermatol.2020.2127)
PHILADELPHIA -- Painful gallstones are common during pregnancy. The pain can be intense, coming on suddenly, increasing and often radiating to the back. When gallstones cause inflammation of the gallbladder, a condition called cholecystitis, the symptoms can worsen, with fever nausea and vomiting in addition to the pain. Surgical removal of the gallbladder is the most effective treatment, but surgery during pregnancy is often feared and at times postponed.
More than 70 million people worldwide suffer from glaucoma, a condition that causes a build-up of fluid and pressure inside the eye and can eventually lead to blindness. Treatment options have traditionally included eye drops to reduce the fluid the eye produces or surgery to unclog the eye's drainage.
Amsterdam and Costa Mesa, CA, August 5, 2020 - As a person's weight goes up, all regions of the brain go down in activity and blood flow, according to a new brain imaging study in the Journal of Alzheimer's Disease.
WASHINGTON -- Researchers have demonstrated a new high-resolution x-ray imaging technique that can capture the motion of rapidly moving objects and quickly changing dynamics. The new method could be used for non-destructive imaging of moving mechanical components and to capture biological processes not previously available with medical x-ray imaging.
(Boston)-- Bisphosphonates (a class of drugs that prevent the loss of bone density and used to treat osteoporosis and similar diseases) appear to be safe and beneficial for osteoarthritis patients.
Osteoarthritis (OA) is the most common form of arthritis and a leading cause of disability worldwide with more than 300 million suffering with the condition, yet there are no effective treatments to stop the disease or its progression. One of the lesions in OA that causes pain and progression of the structural pathology of the disease are bone marrow lesions.
A study led by the Seaver Autism Center for Research and Treatment at Mount Sinai found that two different blood epigenetic signatures associated with ADNP syndrome (also known as Helsmoortel-Van Der Aa syndrome) have only a modest correlation with clinical manifestations of the syndrome. The study results were published online August 5 in the American Journal of Human Genetics.
Eosinophils residing in the airways of mice respond to influenza A virus (IAV) infection through alterations in surface expression of various markers necessary for migration and cellular immunity responses, according to research published in the Journal of Leukocyte Biology by researchers from Le Bonheur Children's Hospital and the University of Tennessee Health Science Center.
DALLAS, August 5, 2020 --The chemicals in cannabis have been linked to an increased risk of heart attacks, heart failure and atrial fibrillation in observational studies; however, a full understanding of how use of cannabis affects the heart and blood vessels is limited by a lack of adequate research, according to a new Scientific Statement from the American Heart Association (AHA) published today in its flagship journal Circulation.
DALLAS, Aug. 5, 2020 -- Recommended medications for peripheral artery disease and coronary artery disease are underused among Hispanic and Latino people, according to new research published today in the Journal of the American Heart Association, an open access journal of the American Heart Association.
In an analysis of women who started pregnancy when taking antidepressant medications, investigators identified three trajectories of antidepressant dispensing during pregnancy: more than half stopped their treatment, a quarter maintained their treatment throughout pregnancy, and one-fifth discontinued it for a minimum of three months and then resumed it during the postpartum period.
A recent analysis of a US commercial insurance database found that adults with rheumatoid arthritis had a lower risk of developing type 2 diabetes than other individuals, including those with other types of arthritis.
The prevalence of gout--a form of arthritis characterized by severe pain, redness, and tenderness in joints--increased across the world at an alarming rate from 1990 to 2017, according to an analysis published in Arthritis & Rheumatology.
The analysis found that there were approximately 41.2 million prevalent cases of gout in 2017, with the rate of new diagnosed cases being 92 per 100,000 people, an increase of 5.5% from 1990.
Smoking has been linked to a higher risk of bone fractures. Researchers have now identified certain lung-related factors that may help to predict an individual smoker's fracture risk. The findings are published in the Journal of Bone and Mineral Research.