Body
Despite disproportionately higher rates of COVID-19 infection, hospitalization and death among people of color, minority groups are significantly underrepresented in COVID-19 clinical trials, according to a new perspective authored by faculty from the University of Georgia and University of Colorado and pharmacists from Phoebe Putney Memorial Hospital in Albany.
As COVID-19 continues to rage across the U.S., researchers are digging deeper into how the virus wreaks havoc on the body, especially for those with a pre-existing chronic illness.
A large European cross-sectional study has now examined which factors delay the diagnosis of axSpA (1). A major factor is the number and type of medical professionals who have assessed the patients.
The European League Against Rheumatism (EULAR) therefore recommends initiating measures to prevent misdirected referrals, to facilitate timely referral of patients with a high probability of axSpA to a rheumatologist and consequently speed up the diagnosis.
Obesity increases the release of tumour-promoting molecules from fat tissue and is associated with an increased risk of breast cancer, according to a study published in Endocrine-Related Cancer. The study found that fat tissue from people with obesity released increased amounts of extracellular vesicles (EV's) enriched in harmful and inflammatory molecules into the blood stream, which can alter breast cancer cells to become more aggressive and invasive.
What if you could simply provide a urine sample rather than undergo a painful surgical procedure to find out if your cancer was responding to treatment? It may seem too good to be true, but researchers at Pavol Jozef Šafárik University in Košice, Slovakia, have identified fluorescent molecules in urine that may allow patients with malignant melanoma to do just that.
Proteins in human cells do not function in isolation and their interactions with other proteins define their cellular functions. Therefore, detailed understanding of protein-protein interactions (PPIs) is the key for deciphering regulation of cellular networks and pathways, in both health and disease.
A study of older mice with type 2 diabetes has yielded highly promising results for researchers investigating potential new vaccines for tuberculosis (TB).
A team of researchers from Australia, Bangladesh and France investigated a potential vaccine, BCG::RD1, and found it highly protective when administered directly into the lungs of diabetic mice, which were then exposed to TB.
Each week a woman consumes alcohol during the first five to 10 weeks of pregnancy is associated with an incremental 8% increase in risk of miscarriage, according to a study by Vanderbilt University Medical Center (VUMC) researchers.
The findings, published in the American Journal of Obstetrics and Gynecology, examine the timing, amount and type of alcohol use during pregnancy and how these factors relate to miscarriage risk before 20 weeks' gestation.
NEW YORK, NY (Aug. 10) -- Only half of pregnant women worldwide who need a treatment developed over 50 years ago to prevent Rh disease--an often-fatal condition in fetuses and newborns that is now exceedingly rare in the United States and Western Europe--actually receive it, finds a study led by researchers at Vagelos College of Physicians and Surgeons (VP&S) at Columbia University Irving Medical Center.
A previous study estimated that complications of the disease may be linked to the deaths of at least 50,000 fetuses and 114,000 newborns worldwide annually.
New York, August 10, 2020 - "I went into the MRI bracing for the wave of panic I knew would come as soon as I was strapped down and inside the machine."
A simple blood test that does not require overnight fasting has been found to be an accurate screening tool for identifying youth at risk for type 2 diabetes and heart disease risk later in life, according to a study from researchers at the Johns Hopkins Bloomberg School of Public Health.
The results suggest that the simple blood test, hemoglobin A1c (HbA1c), should be used more frequently to screen youth for diabetes and related health risks. The HbA1c test is accurate and easy to administer in younger patients.
New Rochelle, NY, August 10, 2020--Gene therapy to the inner retina prevented blindness in a mouse model of the neuro-degenerative disorder CLN3 Batten disease. Adeno-associated viral (AAV)-mediated expression of the human CLN3 gene led to significant survival of bipolar cells and pre-served retinal function, as reported in the peer-reviewed journal Human Gene Therapy. Click here to read the full-text article free on the Human Gene Therapy website through September 10, 2020.
Young adults and adolescents who are prescribed opioids for the first time may be at a slightly greater risk of developing a substance-related problem later in life, according to a new study co-authored by Indiana University researchers. However, the risk may not be as high as previously thought.
The study was published today in JAMA Pediatrics and co-authored by Patrick Quinn, an assistant professor at the IU School of Public Health-Bloomington.
Below please find a summary and link(s) of new coronavirus-related content published today in Annals of Internal Medicine. The summary below is not intended to substitute for the full article as a source of information. A collection of coronavirus-related content is free to the public at http://go.annals.org/coronavirus.
1. Initial weeks of pandemic saw a swift increase in virtual visits, sharp decrease in in-person visits at the VA
Obesity in expectant mothers may hinder the development of the babies' brains as early as the second trimester, a new study finds.
Led by researchers at NYU Grossman School of Medicine, the investigation linked high body mass index (BMI), an indicator of obesity, to changes in two brain areas, the prefrontal cortex and anterior insula. These regions play a key role in decision-making and behavior, with disruptions having previously been linked to attention-deficit/hyperactivity disorder (ADHD), autism, and overeating.