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1. Nalbuphine may help manage opioid-induced urine retention
Abstract: http://annals.org/aim/article/doi/10.7326/L18-0387
URLs go live when the embargo lifts
Nalbuphine may help to manage opioid-induced urine retention. Findings from a brief case report are published in Annals of Internal Medicine.
Scientists have traditionally believed that combining more than two drugs to fight harmful bacteria would yield diminishing returns. The prevailing theory is that that the incremental benefits of combining three or more drugs would be too small to matter, or that the interactions among the drugs would cause their benefits to cancel one another out.
Researchers from Tokyo Metropolitan University and the FIRC Institute of Molecular Oncology (IFOM) in Italy have uncovered a previously unknown function of the DDX11 helicase enzyme. Mutations in the gene which codes for DDX11 are known to be implicated in Warsaw Breakage Syndrome. They showed that DDX11 plays an important role in DNA repair, and functions as a backup to the Fanconi Anemia (FA) pathway, whose malfunction is associated with another life-debilitating condition.
August 31, 2018 - Patient satisfaction after plastic surgery is most affected by surgeon-related factors, such as taking the time to answer questions and including patients in the decision-making process, reports a study in the September issue of Plastic and Reconstructive Surgery®, the official medical journal of the
WASHINGTON --First responders to major chemical exposure incidents in the United States can improve treatment protocols for at-risk casualties with better communication strategies, according to new analysis in Annals of Emergency Medicine.
The evaluation, Operation DOWNPOUR, was funded by the U.S. Department of Health and Human Services (HHS) Biomedical Advanced Research and Development Authority (BARDA), part of the HHS Office of the Assistant Secretary for Preparedness and Response (ASPR).
An intervention designed to facilitate treatment for HIV and substance use was associated with a 50 percent reduction in mortality for people living with HIV who inject illicit drugs, a study has found. In addition, the people who received the intervention were nearly twice as likely to report being in treatment for HIV and substance use after one year as those who received their national standard of care. They also were about twice as likely to have suppressed their HIV to undetectable levels after one year.
DURHAM, NC - Investigators from the HIV Prevention Trials Network (HPTN) today announced The Lancet has published key results from HPTN 074. At 52 weeks from enrollment, participants in the intervention arm nearly doubled their antiretroviral therapy usage, viral suppression and medication-assisted treatment usage compared to the standard of care arm. Mortality was also reduced by more than half with the intervention.
Sept. 5, 2018--A new international guideline has been developed to help physicians diagnosis idiopathic pulmonary fibrosis (IPF), a rare and often fatal lung disease whose cause is unknown.
Exposure to arsenic, lead, copper, and cadmium is associated with increased risk of cardiovascular disease and coronary heart disease, finds a comprehensive analysis of the evidence published today in The BMJ. An accompanying editorial by Ana Navas-Acien at the Columbia Mailman School of Public Health and colleagues points to metals as an important but neglected source of cardiovascular risk.
Exposure to arsenic, lead, copper and cadmium is associated with an increased risk of cardiovascular disease and coronary heart disease, finds a comprehensive analysis of the evidence published by The BMJ today.
In recent years, exposure to environmental toxic metals such as arsenic, lead, copper, and mercury have become a major global health concern.
Arsenic and cadmium, for example, are known carcinogens, but there are increasing suggestions that exposure to toxic metals may be an independent risk factor for cardiovascular disease.
Washington, D.C., -- A new study appearing online today from the American Journal of Psychiatry finds that ketamine's acute antidepressant effect requires opioid system activation, the first time that a receptor site has been shown in humans to be necessary for any antidepressant's mechanism of action. While opioids have been used historically to treat depression, they are known to carry a high risk of dependence. Alan F.
BINGHAMTON, N.Y. - Single-step nasal spray naloxone is the easiest to deliver, according to new research led by faculty at Binghamton University, State University at New York.
Expanded access to naloxone, also known as Narcan®, has been identified as a key intervention for reducing opioid-related deaths. However, there is more than one way to administer it and it is unknown which method is most successful when administered by community members.
Clinicians should consider how the way we think can make us vulnerable to obesity, and how obesity is genetically intertwined with brain structure and mental performance, according to new research.
The study, led by researchers at the Montreal Neurological Institute and Hospital (The Neuro) and published in the Proceedings of the National Academy of Sciences on Aug. 28, 2018, was an examination of magnetic resonance imaging (MRI) and cognitive test data from 1,200 individuals, supplied as part of the Human Connectome Project.
When paramedics resuscitated cardiac arrest patients with a new type of breathing tube, their patients were more likely to survive, according to a University of Texas Health Science Center at Houston (UTHealth)-led study in today's JAMA.
"Based upon these results, use of the newer, more flexible laryngeal breathing tube could result in thousands of saved lives every year," said lead author Henry E. Wang, M.D., M.S., professor and vice chair for research in the Department of Emergency Medicine at McGovern Medical School at UTHealth.
Munich, Germany - Aug. 28, 2018: Low carbohydrate diets are unsafe and should be avoided, according to a large study presented today at ESC Congress 2018.1
Study author Professor Maciej Banach, of the Medical University of Lodz, Poland, said: "We found that people who consumed a low carbohydrate diet were at greater risk of premature death. Risks were also increased for individual causes of death including coronary heart disease, stroke, and cancer. These diets should be avoided."