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Munich, Germany - Aug. 25, 2018: Pregnant women with heart disease should give birth at no later than 40 weeks gestation. That is one of the recommendations in the 2018 European Society of Cardiology (ESC) Guidelines for the management of cardiovascular diseases during pregnancy published online today in European Heart Journal,1 and on the ESC website.2

Munich, Germany - UNDER EMBARGO UNTIL 25 Aug 2018: Very high levels of high-density lipoprotein (HDL or "good") cholesterol may be associated with an increased risk of heart attack and death, according to research presented today at ESC Congress 2018.1

Heart scans for patients with chest pains could save thousands of lives in the UK, research suggests.

The life-saving scans helped to spot those with heart disease so they could be given treatments to prevent heart attacks.

Researchers say current guidelines should be updated to incorporate the scans into routine care.

The SCOT-HEART study tracked more than 4000 patients who were referred to a hospital clinic with symptoms of angina - a condition that restricts the blood supply to the heart.

Kaiser Permanente research published today in the American Journal of Preventive Medicine found if patients with hypertension taking prescribed medications experience unusually low blood pressures -- systolic blood pressure under 110mmHg -- they are twice as likely to experience a fall or faint as patients whose treated blood pressure remains 110mmHg and above.

Bottom Line:  Medicaid expansion under the Affordable Care Act (ACA) was associated with a decline in the proportion of uninsured hospitalizations for major cardiovascular events such as heart attack, stroke and heart failure.

Why The Research Is Interesting: Cardiovascular disease is the leading primary hospital discharge diagnosis and the most common cause of death in the United States. This study examined how state decisions about whether to expand Medicaid under the ACA were associated with changes in uninsured hospitalizations for these major cardiovascular events.

Stanford University researchers have developed a mathematical model that could help public health officials and policymakers curb an opioid epidemic that took the lives of an estimated 49,000 Americans last year.

The model includes data about prescriptions, addictions and overdoses in the United States. It can be used to consider "what if" scenarios similar to those that business leaders run through to project how changing product features or prices are likely to affect sales and profits, said Margaret Brandeau, PhD, professor of management science and engineering.

SEATTLE - A new scientific study concludes there is no safe level of drinking alcohol.

The study, published today in the international medical journal The Lancet, shows that in 2016, nearly 3 million deaths globally were attributed to alcohol use, including 12 percent of deaths in males between the ages of 15 and 49.

Globally, one in three people drink alcohol (equivalent to 2.4 billion people), and 2.2% of women and 6.8% of men die from alcohol-related health problems each year.

Alcohol use was ranked as the seventh leading risk factor for premature death and disability worldwide in 2016, and was the leading cause for people aged 15-49 years old. In this age group, it is associated with tuberculosis, road injuries, and self-harm.

Rockville, Md. (August 23, 2018)--Individual variations in genetic makeup and gut bacteria may explain the different effects of antibiotics on blood pressure, a new rat study suggests. The findings are published ahead of print in Physiological Genomics.

Results from a Movement Disorders study suggest that occupational stress is associated with Parkinson's Disease risk, such that having a high-demand occupation is a risk factor and low control is protective.

High job demands were associated with increased Parkinson's Disease risk among men, especially in men with high education. High control was associated with increased risk among individuals with low education, and this association was more pronounced in women.

Boston--Researchers at Boston Medical Center (BMC) have created a near real-time surveillance method to identify communities experiencing a high burden of drug-resistant tuberculosis in South Africa using routinely collected laboratory data. The team mapped where in the Western Cape Province were the highest rates of drug-resistant tuberculosis and tracked changes over five years.

LA JOLLA--(August 21, 2018) Salk Institute and Purdue University scientists have discovered the switch in plants that turns off production of terpenoids--carbon-rich compounds that play roles in plant physiology and are used by humans in everything from fragrances and flavorings to biofuels and pharmaceuticals.

1. Newer HIV therapies have led to dramatic gains in viral suppression rates over the past 2 decades

Younger persons and blacks saw lower rates of improvement

Abstract: http://annals.org/aim/article/doi/10.7326/M17-2242

Editorial: http://annals.org/aim/article/doi/10.7326/M18-1944

URLs go live when the embargo lifts

DALLAS, August 20, 2018 -- Young, healthy people may still face a lifetime risk of premature death from cardiovascular disease if they cannot keep their cholesterol levels in check, according to new observational research in the American Heart Association's journal Circulation.

DALLAS, Aug. 20, 2018 -- Chagas disease, caused by infection with a parasite called Trypanosoma cruzi (T cruzi), causes chronic heart disease in about one third of those infected. Over the past 40 years, Chagas disease has spread to areas where it had not traditionally been seen, including the United States, according to a new American Heart Association scientific statement published in the American Heart Association journal Circulation.