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Half of clinical trials on the EU register have not reported results, despite rules requiring results to be posted within 12 months of completion, finds a study published by The BMJ today.
Taking high dose folic acid supplements in later pregnancy (beyond the first trimester) does not prevent pre-eclampsia in women at high risk for this condition, finds a randomised controlled trial published by The BMJ today.
However, taking low dose folic acid supplements before and during early pregnancy to prevent birth defects, such as spina bifida, is still strongly recommended for all women, say the researchers.
People who have long-term raised blood pressure have an increased risk of aortic valve disease (AVD) - problems with the valve that controls how blood is pumped from the left ventricle of the heart out into the main artery, the aorta.
Continuity Between Patient and Prescribing Physician Reduces Risky Opioid Prescriptions
Some 23 million prescriptions for opioid painkillers were written in the UK in 2014 at a cost of around £322 million. Misuse is becoming a significant public health issue, including in the US, where the death rate from opioid misuse has quadrupled over the past 15 years, they point out.
But it's not clear whether the rise in opioid use is being driven by need or inappropriate prescribing. To try and find out, the researchers drew on the responses of 5711 people to the national Health Survey for England for 2011.
Your genes can determine how your heart rate and blood pressure respond to exercise - and may act as an early warning of future problems with your heart or blood vessels - according to new research published in The Journal of Physiology.
Differences in the DNA within the mitochondria, the energy-producing structures within cells, can determine the severity and progression of heart disease caused by a nuclear DNA mutation. A new study found that when a nuclear DNA (nDNA) mutation was combined with different mild variants of mitochondrial (mtDNA) in mice, the severity of heart disease was markedly different. One mtDNA variant dramatically worsened heart disease, while another mtDNA variant conferred protection from heart damage.
Utilizing new mobile application technology, researchers at The University of New Mexico found that medical cannabis provides immediate symptom relief across dozens of health symptoms with relatively minimal negative side effects.
New research published in Diabetologia (the journal of the European Association for the Study of Diabetes [EASD]) shows that cardiorespiratory fitness (CRF), high-intensity physical activity (HPA) and low sedentary time (ST) are all associated with a lower risk of type 2 diabetes. The study is by Jeroen van der Velde and Annemarie Koster, Maastricht University, Netherlands, and colleagues.
A recent Finnish study conducted at the University of Jyväskylä showed that adolescents with better aerobic fitness have more compliant arteries than their lower fit peers do. The study also suggests that a higher anaerobic threshold is linked to better arterial health. The results were published in the European Journal of Applied Physiology.
Patients with sepsis are at increased risk of stroke or myocardial infarction (heart attack) in the first 4 weeks after hospital discharge, according to a large Taiwanese study published in CMAJ (Canadian Medical Association Journal).
Sepsis accounts for an estimated 8 million deaths worldwide, and in Canada causes more than half of all deaths from infectious diseases.
CHICAGO, Sept 7, 2018 -- Black adults experience dangerous spikes in high blood pressure, called a hypertensive crisis, at a rate that is five times the national average, according to a study presented at the American Heart Association's Joint Hypertension 2018 Scientific Sessions, an annual conference focused on recent advances in hypertension research.
Whether an individual develops a neurodevelopmental disorder like autism or ADHD and the severity of that disorder depends on genetic changes beyond a single supposedly disease-causing mutation. A new study led by researchers at Penn State reveals that the total amount of rare mutations -- deletions, duplications, or other changes to the DNA sequence -- in a person's genome can explain why individuals with a disease-associated mutation can have vastly different symptoms. A paper describing the study appeared today in the journal Genetics in Medicine.
Montreal, September 6, 2018 - Several new medicines have been found to be more effective than traditional ones used to treat multidrug-resistant tuberculosis (MDR-TB), according to a new international collaborative study led by Dr. Dick Menzies, senior scientist at the Research Institute of the McGill University Health Centre (RI-MUHC) in Montreal. These findings precipitated a complete overhaul of worldwide TB treatment guidelines, with the results of this work published today in the British medical journal The Lancet.