Body

Milan, Italy: Mesothelioma patients are twice as likely to survive for two years or longer, if they are treated with a high dose of radiation to the affected side of the trunk, according to research presented at the ESTRO 38 conference.

Mesothelioma is a rare but aggressive form of cancer that grows in the layers of tissues surrounding the lungs. It is usually caused by exposure to asbestos. Patients typically only live for a year or two following diagnosis and treatment options are very limited.

A new study has shed light on the link between higher body mass index (BMI) and serious health outcomes and death in over 2.8 million adults representative of the UK population.

The disconnect between perceptions of health care providers (HCPs) and people with obesity (PwO) is revealed in a new international study (the ACTION-IO study) presented at this year's European Congress on Obesity (ECO 2019) in Glasgow, UK, and published in the journal Diabetes, Obesity and Metabolism. Among the study's findings are that while 71% of HCPs believe PwO are not interested in losing weight, actually only 7% of PwO report they are not interested - a 10-fold difference.

A study of nearly 50,000 women in Denmark, presented at this year's European Congress on Obesity in in Glasgow, Scotland (28 April-1 May), reveals that those with overweight or obesity in childhood were more likely to develop hypertensive disorders during pregnancy than women of normal weight in childhood. The study is by Dorthe Corfitzen Pedersen, PhD student, the Center for Clinical Research and Prevention at Bispebjerg and Frederiksberg Hospital in Copenhagen, Denmark and colleagues.

New research presented at this year's European Congress on Obesity (ECO) in Glasgow, Scotland (28 April - 1 May) reveals that a quarter of patients have never had their body mass index (BMI) recorded by their GP. The study is by Kath Williamson and Professor Mike Lean of the Department of Human Nutrition and Dr Amy Nimegeer of the Institute of Health and Wellbeing, University of Glasgow, UK.

New research presented at this year's European Congress on Obesity in Glasgow, Scotland (28 April - 1 May) shows that individuals with obesity who commute by car have a 32% higher risk of death, from any cause, compared with those individuals with a normal weight and commute via cycling and walking. The study is by Edward Toke-Bjolgerud, University of Glasgow, UK, and colleagues.

BALTIMORE - A new study identifies antigens targeted by the antibody response of children with Kawasaki Disease (KD). Findings will be presented during the Pediatric Academic Societies (PAS) 2019 Meeting, taking place on April 24 - May 1 in Baltimore.

Researchers have shown that existing optical fibre technology could be used to produce microscopic 3D images of tissue inside the body, paving the way towards 3D optical biopsies.

Unlike normal biopsies where tissue is harvested and sent off to a lab for analysis, optical biopsies enable clinicians to examine living tissue within the body in real-time.

This minimally-invasive approach uses ultra-thin microendoscopes to peer inside the body for diagnosis or during surgery, but normally produces only two-dimensional images.

In Sub-Saharan Africa, the leading causes of death are changing. Fewer people are dying of infectious diseases like malaria or tuberculosis, but non-communicable diseases, including heart disease and diabetes, are on the rise. The situation is particularly grim in South Africa, where citizens are just as likely to die from a non-communicable disease as from anything else.

JUPITER, Fla. - April 29, 2019 - A new study challenges the presumption that people born with developmental brain disorders such as severe autism will benefit from medical interventions only if treated during a narrow window in infancy or early childhood.

Writing in the journal eLife, an open-access scientific journal, the Rumbaugh lab at Scripps Research in Florida reports improvement in measures of seizure and memory in adult mouse models of a genetic cause of autism, called SYNGAP1 disorder.

New study reveals wide variation in spending across the 106 countries, based on whether countries are seeking to control the disease or eliminate it

Development assistance for malaria has plateaued, with 2018 levels virtually unchanged since 2010

Flat-lined funding threatens to stall progress in some low-income countries

SEATTLE - A first-of-its-kind study reveals malaria spending in 2016 totaled $4.3 billion globally, far short of the annual funding target of $6.6 billion set by the World Health Organization.

Lung cancer in people who have never smoked is more common than most people think, and on the rise

Historically strong, and correct, messaging on smoking and lung cancer has inadvertently contributed to lung cancer receiving much less attention than breast, prostate and ovarian cancers

Increasing awareness could help lead to earlier diagnosis, reduce the blame culture around lung cancer and re-balance research funding

A multi-institutional clinical trial has given good results for a targeted therapy to treat a rare, aggressive blood cancer known as blastic plasmacytoid dendritic-cell neoplasm (BPDCN). Details on the trial, which supported Food and Drug Administration approval of the tagraxofusp therapy in December 2018, have been published in the New England Journal of Medicine.

An open-label, multi-cohort Phase II trial, led by investigators at The University of Texas MD Anderson Cancer Center, reports that treatment with the drug tagraxofusp resulted in high response rates in patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN), a rare but highly aggressive - and often fatal bone marrow and blood disorder - for which there are no existing approved therapies.

Women who take antibiotics over a long period of time are at increased risk of heart attack or stroke, according to research carried out in nearly 36,500 women.