Body

Kaiser Permanente researchers find long-term benefits for patients and health organizations that employ screenings, interventions, and referrals.

Screenings, interventions, and referrals can help adolescent teens overcome substance abuse in the short-term. Less is known about the long-term effects of those efforts. A new study from Kaiser Permanente, published in the journal Pediatrics, suggests that the benefits can last for many years and can include sustained reductions in mental health conditions.

Philadelphia, April 23, 2019 - Boys are four times more likely than girls to be diagnosed with autism spectrum disorder (ASD), yet a growing body of research shows that the condition is more common in girls than previously thought, strongly suggesting that new methods are required to diagnose the disorder at younger ages.

April 22, 2019 - "Tummy tuck" surgery (abdominoplasty) can be safely performed in obese patients, with no increase in complications compared to non-obese patients, reports a study in the April issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS).

April 22, 2019 - Even with a good diet and workout routine, some men and women have trouble getting the toned abdominal appearance they want.

Far Eastern Federal University (FEFU) scientists teamed up with colleagues from the UK and Mauritius and experimentally demonstrated that extracts of the endemic (i.e. growing only on this island) medicinal herb leaves Acalypha integrifolia, Eugenia tinifolia, and Labourdonnaisia glauca stop the proliferation of oesophageal squamous carcinoma cells, ones of the most deadly cancer type worldwide. A related article is published in the "Acta Naturae" journal.

In 2015, about half of the world's 28 million human deaths were the result of medical emergencies, with the bulk of the burden borne by poorer nations, according to a statistical analysis of information from nearly 200 countries by a Johns Hopkins Medicine researcher. The analysis, described in April in the journal BMJ Global Health, offered what is believed to be a first-of-its-kind look at the lethal impact of medical emergencies worldwide.

Patients prescribed opioid pain medications whose doses varied over time were 3 times more likely to experience an overdose than patients prescribed stable opioid doses, according to an observational study from Kaiser Permanente published today in JAMA Network Open. The study also showed that patients who discontinued long-term opioid therapy for 3 or more months had half the risk of opioid overdose.

There is an important association between maternal cigarette smoking cessation during pregnancy and risk of preterm birth, according to a new Dartmouth-led study published in JAMA Network Open.

The negative health impacts of cigarette smoking during pregnancy--which include low birth weight, delayed intrauterine development, preterm birth, infant mortality, and long-term developmental delays--are well known. In good news, the proportion of women who start their pregnancy as smokers has been declining in recent years.

ATLANTA --In a commentary published in the American Journal of Kidney Diseases, public health researchers suggest adjustments to recently proposed rule changes on how Medicare pays for dialysis services.

Medicare spends approximately $35 billion annually on care for beneficiaries with end-stage renal disease (kidney failure), more than 7 percent of Medicare's total paid claims. Over half a million people receive regular dialysis treatments to manage this condition, with treatment costs averaging about $85,000 a year, according to the study.

New Rochelle, NY, April 18, 2019--Gene therapy offers the promise of a cure for beta-thalassemia and a new study has shown that it is associated with fewer complications and hospital admissions over 2 years than treatment by allogeneic hematopoietic stem cell transplantation (HSCT). The study, which analyzes and compares the effectiveness and cost of gene therapy versus (HSCT) in patients with major beta-thalassemia is published in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

Reducing the sugar content of certain foods by 2020, in line with UK government policy targets, could cut child obesity and related illness, and save the NHS in England £286 million over 10 years, suggests a study published by The BMJ today.

But these benefits could be easily lost if the targets are not fully met, or if the programme leads to unintended changes in consumer or industry behaviour, warn the researchers.

In the largest study of its kind, researchers from the Musculoskeletal Research Unit at the University of Bristol have identified the most important risk factors for developing severe infection after knee replacement. Patients who are under 60 years of age, males, those with chronic pulmonary disease, diabetes, liver disease, and a higher body mass index are at increased risk of having the joint replacement redone (known as revision) due to infection.

The commonly used diabetes drug metformin could reverse the harmful thickening of heart muscle that leads to cardiovascular disease, according to a study at the University of Dundee.

Scientists led by Professor Chim Lang, Head of the Division of Molecular and Clinical Medicine at Dundee, discovered that metformin has the potential to be repurposed as a heart disease treatment in non-diabetic patients.

Bioelectronic medicine scientists at The Feinstein Institute for Medical Research collaborated with counterparts from Academic Medical Center at University of Amsterdam in the Netherlands to carry out a series of pilot clinical studies to assess the effect of a novel bioelectronic stimulation. These studies show that non-invasive stimulation at the external ear improves disease symptoms in patients with rheumatoid arthritis (RA). These findings were first published today in Bioelectronic Medicine.

CLEVELAND, Ohio (April 17, 2019)--Vaginal dryness and painful intercourse are some of the more common adverse events of post-breast cancer treatment therapies and often lead to sexual dissatisfaction and an overall lower quality of life (QOL). However, a new study finds that partnered women may fare better than those without a partner. Study results are published online today in Menopause, the journal of The North American Menopause Society (NAMS).