Body

PITTSBURGH--A team of researchers from Carnegie Mellon University has published a paper in Science that details a new technique allowing anyone to 3D bioprint tissue scaffolds out of collagen, the major structural protein in the human body. This first-of-its-kind method brings the field of tissue engineering one step closer to being able to 3D print a full-sized, adult human heart.

Allergies can be life-threatening when they cause anaphylaxis, an extreme reaction with constriction of the airways and a sudden drop in blood pressure. Scientists have identified a subtype of immune cell that drives the production of antibodies associated with anaphylaxis and other allergic reactions.

(PHILADELPHIA) - A rare, short-lived population of immune cells in the bloodstream may serve as 'periscopes' to monitor immune status via lymph nodes deep inside the body, according to researchers in the Perelman School of Medicine at the University of Pennsylvania. Their findings are published this month in the Journal of Clinical Investigation (JCI).

PHILADELPHIA (August 1, 2019) - More than 1 million sepsis survivors are discharged annually from acute care hospitals in the United States. Although the majority of these patients receive post-acute care (PAC) services, with over a third coming to home health care (HHC), sepsis survivors account for a majority of readmissions nationwide. Effective interventions are needed to decrease these poor outcomes.

What The Study Did: The financial and environmental costs of unused portions of drugs from cataract surgery at four surgical sites in the U.S was investigated in this study.

Authors: Cassandra L. Thiel, Ph.D., of the New York University School of Medicine in New York, is the corresponding author

(doi:10.1001/jamaophthalmol.2019.2901)

Editor's Note: The article includes conflict of interest disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

Biomedical researchers at KU Leuven have found a new way to study endometrial diseases such as endometriosis and cancer. They were able to grow three-dimensional cell structures from diseased tissue of patients. The biobank can be used to unravel the disorders and test drugs.

Edinburgh has some of the highest known rates of inflammatory bowel disease in the world and the figure is expected to rise in the next 10 years.

Researchers say that one in 125 people in the city have Crohn's disease or ulcerative colitis - collectively known as inflammatory bowel disease (IBD).

They predict this figure will rise to 1 in 98 by 2028, putting further strain on NHS resources.

A group of European scientists led by KU Leuven has found a biomarker that can identify patients with symptoms of kidney rejection symptoms after a transplant as a result of antibodies. The identification can be done through a simple blood test and at an early stage. It is the first known biomarker for rejection by antibodies. The researchers hope that the test can be further developed quickly for use in the hospital.

JACKSONVILLE, Fla. -- Known for its poor prognosis, lung adenocarcinoma is the most common type of lung cancer, responsible for about 4 of 10 diagnoses, according to the National Cancer Institute. Researchers on Mayo Clinic's Florida campus can now distinguish between two pathways where this deadly cancer can develop. They say their discovery could help future patients. The findings appear in Cancer Cell.

August 1, 2019 -- From risks of violence and abuse to disrupting their development, humanitarian crises present major threats to the wellbeing of children, and for more than two decades Child Friendly Spaces have been considered one of the best ways to respond.

A new study, led by Professor Elina Hyppönen from UniSA's Australian Centre for Precision Health, presents the strongest evidence yet of a causal relationship between obesity and a wide range of serious conditions, including cardiovascular disease, diabetes, cancer, and neurological, musculoskeletal and respiratory afflictions.

The real burden of tuberculosis is probably higher than estimated, according to a study on samples from autopsies performed in a Mozambican hospital. The study, led by the Barcelona Institute of Global Health (ISGlobal), an institution supported by "la Caixa", shows that highly sensible molecular techniques can detect cases that escape clinical diagnosis and even traditional post-mortem examination of organs and tissues.

Researchers at the Stanford University School of Medicine have discovered a new signal that cancers seem to use to evade detection and destruction by the immune system.

The scientists have shown that blocking this signal in mice implanted with human cancers allows immune cells to attack the cancers. Blocking other "don't eat me" signals has become the basis for other possible anti-cancer therapies.

Scientists have created a microneedle patch based on the fangs of a snake that can deliver therapeutic liquids and a vaccine through the skin of rodents in under 15 seconds. Their device circumvents the pumping systems and extra drug preparation steps associated with previous microneedle patches, indicating it could serve as a flexible and easy-to-use drug delivery platform. Medicinal liquids and vaccines are usually delivered with hypodermic needles, but needles carry a risk of infection and are frequently painful.