Body
A study published in Cell Reports Aug. 6 describes the generation of a new mouse model developed at Hollings Cancer Center that could lead to a better understanding of the cachexia syndrome. This wasting condition, characterized by excessive weight loss, has one of the highest incidences in pancreatic cancer patients.
NEW YORK, August 6, 2019-- Researchers from TARA Biosystems, Inc. and GlaxoSmithKline (GSK) today published data demonstrating that TARA's engineered heart-on-a-chip system replicated drug responses found in adult humans.
High blood pressure is the most important treatable risk factor for diseases of the heart and the arterial system. Blood pressure recorded over 24 hours predicts these complications more accurately than blood pressure measured on a single occasion. That is the conclusion of an international study coordinated by Professors Jan A. Staessen and Zhen-Yu Zhang of KU Leuven in Belgium. Dr. Gladys Maestre from the University of Texas, Rio Grande Valley School of Medicine, supervised the study in Venezuela, one of the participating countries.
WASHINGTON --Researchers for the first time have combined a powerful microscopy technique with automated image analysis algorithms to distinguish between healthy and metastatic cancerous tissue without relying on invasive biopsies or the use of a contrast dye.
This new approach could one day help doctors detect cancer metastasis that is otherwise difficult to see via standard imaging technologies during operations.
New York, NY--August 6, 2019--By adding electronics and computation technology to a simple cane that has been around since ancient times, a team of researchers at Columbia Engineering have transformed it into a 21st century robotic device that can provide light-touch assistance in walking to the aged and others with impaired mobility.
A new study from researchers at the University of Cincinnati (UC) and Cincinnati Children's looks at the prevalence of abnormal thyroid function in youth with severe mood and anxiety disorder. It is the largest study to date of this population and will help mental health professionals better understand the predictors of abnormal thyroid function, like weight gain, family history or treatment with certain medications.
Pivotal response treatment involving parents works better than other existing therapies at motivating children with autism and significant speech delays to talk, according to the results of a large study by researchers at the Stanford University School of Medicine.
Because children with autism are less socially motivated than typically developing children, parents' instincts about how to engage them often don't succeed, said Grace Gengoux, PhD, clinical associate professor of psychiatry and behavioral sciences. PRT gives parents a way to breach this barrier.
'Spin'--exaggerating the clinical significance of a particular treatment without the statistics to back it up--is apparent in more than half of clinical trial abstracts published in top psychology and psychiatry journals, finds a review of relevant research in BMJ Evidence Based Medicine.
The findings raise concerns about the potential impact this might be having on treatment decisions, as the evidence to date suggests that abstract information alone is capable of changing doctors' minds, warn the study authors.
A new study in Cardiovascular Research finds that female offspring of females with polycystic ovary syndrome have an increased risk for developing cardiac dysfunction.
Polycystic ovary syndrome is the most common reproductive disorder, affecting one in 10 women of childbearing age. Women with disorder may have infrequent or prolonged menstrual periods or excess male hormone (androgen) levels, making pregnancy more difficult. The disorder is also associated with developing type 2 diabetes, depression, high blood pressure, and uterine cancer.
WASHINGTON -- Students identifying as black or Latino are more likely to say they would socially distance themselves from peers with a mental illness, a key indicator of mental illness stigma, according to research published by the American Psychological Association. The findings reinforce how stigma may prevent teens who face prejudice and discrimination from seeking help for a mental health problem when they need it.
Children's veins are small and sometimes difficult to access during necessary medical treatment. When caregivers used ultrasound to guide placement of intravenous (IV) lines in children with presumed difficult access, they had higher success rates on their first attempt. Researchers from Children's Hospital of Philadelphia (CHOP) report that this technique reduces the number of needle sticks in their young patients.
The research was published in the July 2019 issue of Annals of Emergency Medicine.
People who spend eight or more hours a day staring at a computer screen may notice their eyes becoming tired or dry, and, if those conditions are severe enough, they may eventually develop dry eye disease (DED). DED is a common disease with shockingly few FDA-approved drug options, partially because of the difficulties of modeling the complex pathophysiology in human eyes. Enter the blinking eye-on-a-chip: an artificial human eye replica constructed in the laboratory of Penn Engineering researchers.
BOSTON -Successful recovery from opioid use disorder appears to be even more challenging than recovery from alcohol use disorder, and individuals with opioid use problems may require more intensive medical, psychological and social support services over a longer period of time, results of the first national study of opioid problem resolution suggest.
A team of scientists in Korea and the United States have invented a device that can control neural circuits using a tiny brain implant controlled by a smartphone.
Researchers, publishing in Nature Biomedical Engineering, believe the device can speed up efforts to uncover brain diseases such as Parkinson's, Alzheimer's, addiction, depression, and pain.
The device, using Lego-like replaceable drug cartridges and powerful bluetooth low-energy, can target specific neurons of interest using drug and light for prolonged periods.
In a new study from SciLifeLab at Uppsala University, researchers have found a total of 141 regions (genes) in our genetic material that largely explain the genetic risk underlying asthma, hay fever and eczema. As many as 41 of the genes identified have not previously been linked to an elevated risk for these diseases. The results are published in the scientific journal Human Molecular Genetics.