Body

BOSTON, July 30, 2019 -- In laboratory tests, a compound found in soybeans blocked damage to the lining of blood vessels in the heart and circulatory system and may someday provide a way to prevent the cardiovascular side effects of recreational and medical marijuana use, according to preliminary research presented at the American Heart Association's Basic Cardiovascular Sciences 2019 Scientific Sessions.

Women with pre-eclampsia during pregnancy have a five-fold increased risk of end stage kidney disease (ESKD) later in life compared to women who don't develop pre-eclampsia during pregnancy, according to a new study published this week in PLOS Medicine by Ali Khashan of University College Cork, Ireland, and colleagues at the Karolinska Institute, Sweden and Liverpool University, UK.

A research collaboration led by scientists from institutions in Japan including Tokyo University of Agriculture and Technology (TUAT) has developed a new experimental cancer model for dog bladder cancer. Urine samples were used for a 3D cell culture method called organoid culture. This method will allow us to quickly determine the proper chemotherapy and to identify new biomarkers of both dog and human bladder cancer in the near future.

The researchers published their results on July 23rd in Cancer Science.

A new multi-national survey has revealed that asthma sufferers are missing nearly one-tenth of work hours due to their symptoms, which also results in a loss of productivity and affects their emotional wellbeing.

The World Health Organisation estimates that 235 million people around the world suffer from asthma. But little is known about the impact of asthma on symptomatic people's ability to work.

Retinitis pigmentosa (RP) is a common hereditary eye disorder that leads to the gradual deterioration of rod cells causing reduced peripheral vision and night vision. Subsequent loss of cone photoreceptors cause the loss of high-resolution daylight and color vision.

Ophthalmology researchers at the University of Louisville have discovered the loss of vision in RP is the result of a disruption in the flow of nourishing glucose to the rods and cones. This disruption leads to the starvation of the photoreceptors.

HOUSTON - (July 30, 2019) One of the most extensively studied genes in cancer, TP53 is well known for its role as a tumor suppressor. It senses cellular stress or damage, and in response stops cell division or initiates cell death, thereby preventing a damaged cell from reproducing. Mutation of this gene eliminates a key cellular fail-safe mechanism and is a step leading to cancer. Researchers at Baylor College of Medicine have conducted the most comprehensive study of TP53 mutations to better understand the processes leading to the inactivation of this important gene.

OAK BROOK, Ill. - Smoking reduces the chances of a successful procedure to treat blood vessel abnormalities in the lungs, according to a study published in the journal Radiology.

Pulmonary arteriovenous malformations (PAVMs) are abnormal connections between arteries and veins in the lungs. The abnormalities can become symptomatic and lead to potentially dangerous complications. PAVMs are strongly associated with an inherited disorder called Hereditary Hemorrhagic Telangiectasia (HHT).

UNIVERSITY PARK, Pa. - The devastating consequences of the opioid crisis are far-reaching in the United States, impacting public health as well as social and economic welfare. Penn State researchers recently collaborated to address the issue in a supplement of The American Journal of Managed Care titled "Deaths, Dollars, and Diverted Resources: Examining the Heavy Price of the Opioid Epidemic."

DALLAS, July 30, 2019 - Less-invasive procedures to open severely-clogged leg arteries were as good at helping people survive and avoid amputation as more invasive open surgeries, according to a study reported in Circulation: Cardiovascular Quality and Outcomes, an American Heart Association journal.

CAMBRIDGE, MA -- More than 15 million colonoscopies are performed in the United States every year, and in at least 20 percent of those, gastroenterologists end up removing precancerous growths from the colon. Eliminating these early-stage lesions, known as polyps, is the best way to prevent colon cancer from developing.

To reduce the risk of tearing the colon during this procedure, doctors often inject a saline solution into the space below the lesion, forming a "cushion" that lifts the polyp so that it's easier to remove safely. However, this cushion doesn't last long.

An IMAS-led study of seabirds that had ingested plastic debris has revealed a range of non-lethal impacts on their health and physiology.

While seabird deaths due to swallowing plastic debris or becoming entangled in it have received global attention, the non-lethal effects on seabirds that survive plastic ingestion are less well-known.

The study led by IMAS' Dr Jennifer Lavers and published in the journal Environmental Science & Technology has found that plastic ingestion can have a significant negative impact even on superficially healthy seabirds.

Massive hemorrhage, or excessive bleeding, is a potentially preventable yet a major cause of death in trauma patients.

An immediate and well-balanced transfusion of blood components, such as platelets and red blood cells (RBCs) which, respectively form clots to stop bleeding and deliver oxygen to tissues and organs for proper function, becomes crucial for their survival.

AUGUSTA, Ga. (July 30, 2019) - It's the proportionality of a newborn -- a measure that includes both birthweight and length -- that may best tell doctors whether a child is born with an increased risk for heart problems later in life, investigators report.

Below please find summaries of new articles that will be published in the next issue of Annals of Internal Medicine. The summaries are not intended to substitute for the full articles as a source of information.

1. Candida auris is a new drug-resistant fungus emerging globally and in the U.S. Early detection is key to controlling spread of deadly drug-resistant fungus

Physicians should be aware of risk factors and screen patients suspected of infection or colonization

BOSTON, July 29, 2019-- Measuring a menopausal woman's pulse wave at her wrist may help explain the increase in cardiovascular disease risk during menopause better than a standard blood pressure measurement, according to preliminary research presented at the American Heart Association's Basic Cardiovascular Sciences 2019 Scientific Sessions.

While research shows that age, gender and body mass index (BMI) play important roles in cardiovascular disease risk, it's not clear why the risk spikes when women are in menopause.