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Kanazawa, Japan - The compound thymoquinone (TQ) selectively kills prostate cancer cells at advanced stages, according to a new study published in Oncogene. Led by researchers at Kanazawa University, the study reports that prostate cancer cells with a deletion of the SUCLA2 gene can be therapeutically targeted. SUCLA2-deficient prostate cancers represent a significant fraction of those resistant to hormone therapy or metastatic, and a new therapeutic option for this disease would have immense benefits for patients.
(Jena, Germany) At the latest since the Nobel Prize in Physics was awarded for research on graphene in 2010, 2D materials - nanosheets with atomic thickness - have been a hot topic in science.
86% of UK residents who tested positive for COVID-19 during lockdown did not have the specific virus symptoms (cough, and/or fever, and/or loss of taste/smell), finds a new study by UCL researchers. The authors say a more widespread testing programme is needed to catch 'silent' transmission and reduce future outbreaks.
PLYMOUTH MEETING, PA [October 7, 2020] -- New research in the October 2020 issue of JNCCN--Journal of the National Comprehensive Cancer Network finds the rate of bone mineral density (BMD) testing in people with prostate cancer undergoing androgen deprivation therapy (ADT) has improved in recent years, but remains low. ADT is considered a cornerstone of treatment for high-risk or advanced prostate cancer and is used in nearly half of all prostate cancer patients. However, it can result in preventable side effects like osteoporosis and bone fractures.
Oral cancer is more likely to spread in patients experiencing high levels of pain, according to a team of researchers at New York University (NYU) College of Dentistry that found genetic and cellular clues as to why metastatic oral cancers are so painful.
The findings--which appear in Scientific Reports, a journal published by Nature--may ultimately be used to alleviate oral cancer pain and refine surgical decision making when treating oral cancer.
From Covid-19- to COVID-20 - the evolution of COVID-19 in terms of its overall medical and socio-economic impacts is examine through a comparison of cases and deaths in the two successive waves we have experienced. Peak comparisons show that although the number of cases has doubled the number of deaths has decreased by 50 percent with case mortality decreasing by a factor of four.
WINSTON-SALEM, N.C. - Oct. 7, 2020 - Is this person with chest pain having a heart attack? That's a question EMTs frequently confront when responding to 911 calls.
A study conducted at Wake Forest Baptist Health shows that on-scene use of a new protocol and advanced diagnostic equipment can help paramedics better identify patients at high risk for adverse cardiac events. This approach could help paramedics determine the hospital best equipped to treat those people.
The study is published in the Oct. 7 edition of the journal PLOS One.
Since the outset of the COVID-19 pandemic, there has been much debate about the danger to hospital staff from anaesthetic procedures. Concerns include that placing a tube in the patient's airway (intubation) before surgery or removing it at the end (extubation) may produce a fine mist of small particles (called aerosols) and spread the COVID-19 virus to nearby staff.
Fostamatinib is approved for the treatment of chronic immune thrombocytopenia in adults who are refractory to other treatments (in particular to treatment with corticosteroids). The German Institute for Quality and Efficiency in Health Care (IQWiG) examined in an early benefit assessment whether fostamatinib offers an added benefit for these patients in comparison with eltrombopag or romiplostim.
A drug has shown great promise in the treatment of neuroblastoma, an aggressive form of childhood cancer. The study was led by researchers at Lund University in Sweden, and is published in the journal Science Translational Medicine.
Imaging techniques could replace the need for invasive tissue biopsies in helping rapidly determine whether cancer treatments are working effectively, according to researchers at the University of Cambridge.
In a study published in the journal Cancer Cell, researchers at the Cancer Research UK (CRUK) Cambridge Institute have shown how a new technique known as hyperpolarisation - which involves effectively magnetising molecules in a strong magnetic field - can be used to monitor how effective cancer drugs are at slowing a tumour's growth.
A diet high in sugar during adulthood is associated with weight gain, and has also been linked to risk of type 2 diabetes, fatty liver disease, and heart disease. New research shows that when consumed by moms during the breastfeeding period, a high sugar diet can also impact developmental outcomes during infancy.
(Boston) - Being previously infected with a coronaviruses that cause the "common cold" may decrease the severity of severe acute respiratory syndrome coronavirus (SARS-CoV-2) infections, according to results of a new study. Led by researchers at Boston Medical Center and Boston University School of Medicine, the study also demonstrates that the immunity built up from previous non-SARS-CoV-2 coronavirus infections does not prevent individuals from getting COVID-19.
COLUMBUS, Ohio - Appeals seeking donations to help fight hunger during the COVID-19 pandemic were more successful when the typeface in which the appeal was written mirrored the tone of the donation request, a new study has found.
The Barcelona Institute for Global Health (ISGlobal), a center supported by the "la Caixa" Foundation, in coordination with the City University of New York Graduate School of Public Health & Health Policy (CUNY SPH) and other international institutions, has developed an easy and reliable tool to evaluate the public perception of governmental response to the COVID-19 pandemic.