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New Rochelle, NY, October 6, 2020—Battling the COVID-19 pandemic and preparing for the inevitable next surge requires a data-driven population health approach. A special issue of the peer-reviewed journal Population Health Management is dedicated to combatting COVID-19. It embraces systems thinking and key insights from other industries. Click here to read the issue now.
CHAMPAIGN, Ill. -- In a collaborative effort between scientists and personnel on military bases in 31 states in the continental U.S. and Puerto Rico, researchers surveyed for an infection caused by an emerging fungal pathogen that afflicts snakes. The effort found infected snakes on military bases in 19 states and Puerto Rico, demonstrating that the fungus is more widely distributed than was previously known. The team reports the findings in the journal PLOS ONE.
Malignant tumours of the peripheral nerve are rare but aggressive and very difficult to treat successfully. Now, researchers in the US have shown that a combination of two types of anti-cancer drugs, MEK and SHP2 inhibitors, is effective in targeting the mechanism that drives the cancer's growth.
The coronavirus pandemic has widened existing gaps in access to abortion services across Europe, finds a review of country-wide policy changes in response to COVID-19, published in the journal BMJ Sexual & Reproductive Health.
But enforced innovations adopted in some countries, such as telemedicine and the provision of abortion at home, could reverse that trend and prompt long lasting change for this essential health service, suggest the researchers.
An international research team has discovered a principle that explains the metastasising of prostate cancer. When cancer evolves within the prostate, multiple spatially intermixed cancer cell clones are created that may invade the organs surrounding the prostate. However, only one dominant cell clone spreads systemically in the body and creates metastases. In addition, new subcellular clones are often generated in metastases, which pass on to other metastases.
Reston, VA--A new radioimmunotherapy has proven effective in reversing resistance to the most commonly used lymphoma drug, rituximab, according to research published in the October issue of The Journal of Nuclear Medicine. When used in combination with rituximab, 177Lu-lilotomab-satetraxetan was shown to substantially increase rituximab binding and rituximab-mediated antibody-dependent cellular cytotoxicity (ADCC) activity, resulting in significant tumor growth delay in a non-Hodgkin's lymphoma mouse model.
People use, trust different COVID-19 information sources depending on gender, age, and other factors
Gender, age, education level, and political affiliation predict where people turn for information about COVID-19--and what sources they use and trust is linked to differing beliefs about the pandemic, according to a new study by NYU School of Global Public Health researchers.
The findings--drawn from surveys of more than 11,000 U.S. adults during the first few months of the pandemic--are published in JMIR Public Health and Surveillance.
By José Tadeu Arantes | Agência FAPESP – The most widely used model to describe the epidemic evolution of a disease over time is called SIR, short for susceptible (S), infected (I), and removed (R). A susceptible person can be infected, and the infected person will eventually be removed owing to either immunization or death. The number of people in each class varies, whereas the total population, given by the sum of individuals in all three classes, is considered constant in the time scale of epidemic contamination.
Pregnant women with severe or critical COVID-19 and their unborn infants face increased health risks before and after delivery, a Rutgers study finds.
Meanwhile, the study, published in the American Journal of Obstetrics and Gynecology, also found that pregnant women with mild cases of coronavirus disease 2019 had similar outcomes compared to those who were uninfected.
A study published in the scientific journal Addiction suggests that, contrary to what some are claiming, people in the US may not be substituting cannabis for opioids.
Contrary to some claims, people in the U.S may not be substituting cannabis for opioids, according to new research at Columbia University Mailman School of Public Health. The study examined the direction and strength of association between cannabis and opioid use over 90 consecutive days among adults who used non-medical opioids. The findings showed that opioid use was at least as prevalent on days when cannabis was used as on days when it was not, and that this was irrespective whether participants were experiencing pain or not.
In a clinical trial testing two different forms of "nudging," statin prescriptions at the right dosages increased significantly among patients with heart disease when doctors had to actively choose whether or not to prescribe the medications, which are used to lower cholesterol. However, for patients who were just deemed at-risk for heart disease, neither an active choice nudge nor a more passive one affected prescribing rates. The results were published today in JAMA Cardiology.
Several predictions made by experts ahead of the UK-wide lockdown in March are confirmed in a detailed re-analysis of the data published by The BMJ today.
A report produced by researchers from Imperial College London was reported to be the main evidence behind lockdown decisions taken by the UK government in March 2020.
The Imperial College report was based on a detailed model of interactions between people in the UK. The model predicted how the virus would spread, how the NHS would be affected, and how many would die in different scenarios.
Reston, VA--A new intraoperative imaging technique, Cerenkov luminescence imaging (CLI), can accurately assess surgical margins during radical prostatectomy, according to a first-in-human research published in the October issue of the Journal of Nuclear Medicine. The feasibility study showed that 68Ga-PSMA CLI can image the entire excised prostate specimen's surface to detect prostate cancer tissue at the resection margin.