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Results of a first-of-its-kind clinical trial shed light on when antibiotics instead of surgery might be the better choice for treating appendicitis in some patients, according to researchers with The University of Texas Health Science Center at Houston (UTHealth), who led the Houston trial sites.

The results from the national Comparing Outcomes of Antibiotic Drugs and Appendectomy (CODA) trial were published today in the New England Journal of Medicine.

A UC Davis MIND Institute study of pregnant mice found that high amounts of folic acid during pregnancy harmed the brain development of embryos. Researchers say the findings indicate that more investigation is needed about the best recommended dosage for pregnant women.

"We believe there's a Goldilocks effect with folic acid. Too little is not good, too much is not good; you have to get it just right," said Ralph Green, UC Davis distinguished professor of pathology and medicine and a corresponding author of the study.

Antibiotics may be a good choice for some, but not all, patients with appendicitis, according to results from the Comparing Outcomes of antibiotic Drugs and Appendectomy (CODA) Trial reported today in the New England Journal of Medicine. The findings indicated that antibiotics were not worse than surgery when measuring overall health status, allowing most people to avoid an operation in the short term.

CHICAGO - Universal COVID-19 testing of children who are having procedures requiring anesthesia promotes efficient use of personal protective equipment (PPE), according to research being presented at the ANESTHESIOLOGY® 2020 annual meeting.

CHICAGO: Limited English-language proficiency (LEP) is a risk factor for getting potentially lifesaving screening mammograms less often, according to new study results using national data. These findings, from women aged 40 and older living in the United States, are presented at the American College of Surgeons (ACS) Clinical Congress 2020.

CHICAGO: Young women with benign breast conditions may undergo surgery without jeopardizing their ability to breastfeed later on. One of the first studies to specifically evaluate the effects of surgery on breastfeeding outcomes and lactation capability reveals that more than 80 percent of young women successfully breast-fed or bottle-fed breast milk, including those with a history of a prior breast operation. Findings from the study were presented as a clinical poster at the virtual American College of Surgeons Clinical Congress 2020.

CHICAGO: Among accredited U.S. cancer centers, hospitals serving primarily minority patients are as likely as other hospitals to offer the standard of surgical care for early-stage breast cancer, according to results presented at the virtual American College of Surgeons (ACS) Clinical Congress 2020.

CHICAGO: To address the opioid epidemic, surgeons have embraced guidelines to reduce the number of opioid pills they prescribe to patients after surgery, and the efforts have helped to significantly reduce the number of opioids in circulation. But new research presented at the virtual American College of Surgeons Clinical Congress 2020 reports that these guidelines may be missing a small group of patients that need a greater level of pain control.

One of the key challenges in developing effective, targeted cancer treatments is the heterogeneity of the cancer cells themselves. This variation makes it difficult for the immune system to recognize, respond to and actively fight against tumors. Now, however, new advances in nanotechnology are making it possible to deliver targeted, personalized "vaccines" to treat cancer.

Leesburg, VA, October 2, 2020--According to an open-access article in ARRS' American Journal of Roentgenology (AJR), dual-energy CT (DECT) added value to routine interpretation of emergency department (ED) imaging studies by increasing radiologists' diagnostic confidence, leading to a reduction in downstream imaging and associated costs.

Despite increased use of telemedicine during the COVID-19 pandemic, Americans have had significantly fewer consultations with primary care doctors and markedly fewer assessments of common cardiac risk factors, according to a new study led by researchers at Johns Hopkins Bloomberg School of Public Health.

What The Study Did: This observational study quantified national changes in the volume, type and content of primary care delivered during the COVID-19 pandemic, especially with regard to office-based visits compared with telemedicine encounters.

Authors: G. Caleb Alexander, M.D., M.S., of the Johns Hopkins Bloomberg School of Public Health in Baltimore, is the corresponding author.

To access the embargoed study:  Visit our For The Media website at this link https://media.jamanetwork.com/ 

Denver--October 2, 2020--Next-generation sequencing (NGS) of cell-free DNA (cfDNA) obtained from blood samples may improve diagnostic testing in patients with advanced NSCLC, and may also be faster and less expensive compared to standard tissue profiling, according to research presented today at the IASLC 2020 Lung Cancer Hot Topic: Liquid Biopsy Virtual Conference.

Denver--October 2, 2020--A pilot study comparing the effects of a liquid biopsy with tissue-based test showed that liquid biopsy turn-around time for results was approximately 10 days faster than the tissue biopsy, according to research presented today at the IASLC 2020 Lung Cancer Hot Topic: Liquid Biopsy Virtual Conference.

The results of a recent study moved University of Arizona Health Sciences researchers one step closer to developing effective vaccinations against flaviviruses, which infect more than 400 million people a year with diseases such as dengue, yellow fever, West Nile, Zika and Japanese encephalitis.